Protein

Protein accession
A0AAE8XD15 [UniProt]
Representative
48uUY
Source
UniProt (cluster: phalp2_25618)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MKVKFKKREQTTKVILVSAQDDKGSRQLNMEARSGGSLHHGYHYVIRSDGTVEEGRAHDEVSSFRDKTAIYVRENHMCPPPPPSLVFDEWAGLEFVKMKEEDIG
Physico‐chemical
properties
protein length:104 AA
molecular weight:11861,3 Da
isoelectric point:6,51
hydropathy:-0,77
Representative Protein Details
Accession
48uUY
Protein name
48uUY
Sequence length
255 AA
Molecular weight
27448,24220 Da
Isoelectric point
8,66785
Sequence
MCGPGWAHTARAPVAQRRRTTHLVFHTAAWPGDPSAADIDRAHRQRGFSRIGYHYVVRKDGTVEEGRAEGQVGAHCRDGGMNPVSVGVCFSGHHGDDYHGVQGEEWTDAQRAAWHELAAGLVDRYGIAIENVIGHREAGAKKACPGDRVDCDAVRRDLARHMATRDAGDVSTDTPTPPASVTTQPRPLLRRGARGRDVGDLQRALKTAGLYAGKIDGDFGPVTDRALRAFQARRGLEVDGLAGPNTWAALDRAGL
Other Proteins in cluster: phalp2_25618
Total (incl. this protein): 31 Avg length: 204,2 Avg pI: 8,41
Protein ID Length (AA) pI
48uUY 255 8,66785
11mlk 231 9,97888
1bxMg 182 6,58545
267Ti 230 5,39046
28tC5 230 5,42940
2YHms 246 9,78535
2sVbN 225 9,29816
3FuPk 229 9,24278
3ZhLh 189 9,43471
3mN80 229 7,95148
4OVfL 193 10,26177
4Pshm 193 10,33701
4W0LK 188 9,29926
4qXRh 229 4,60358
5HqTa 240 10,48296
5qQum 251 7,26075
5yFoL 251 7,26075
5yNjN 226 7,15599
6Qhm7 188 9,67124
6Ql0N 169 9,29803
7dhbe 219 9,32743
7pqLK 188 9,21783
7pqLR 188 9,48093
7pqN5 188 9,40344
7s3DS 219 9,54514
7s3F7 219 8,49611
8MgwL 173 10,01705
yQRR 251 6,85748
A0A7S6HSB2 104 7,89849
A0A8A6C5V8 104 6,50979
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_19675
4Bope
 30 37,8% 230 1.396E-43
2 phalp2_36521
1qwup
 277 36,4% 239 2.606E-43
3 phalp2_36904
7xR8d
 63 35,4% 240 1.122E-36
4 phalp2_37752
4kTIO
 51 33,3% 225 3.434E-35
5 phalp2_26274
RjMA
 376 28,4% 250 1.047E-33
6 phalp2_35819
4CbZx
 312 33,0% 209 6.745E-33
7 phalp2_2920
NQqI
 114 32,0% 250 5.916E-32
8 phalp2_12381
8yxE3
 11 38,7% 155 7.325E-29
9 phalp2_37317
7ZZsG
 35 30,9% 262 2.981E-27
10 phalp2_35681
3yvcZ
 6 37,2% 188 8.854E-26

Domains

Domains [InterPro]
Ami2
PG_1
Representative sequence (used for alignment): 48uUY (255 AA)
Member sequence: A0AAE8XD15 (104 AA)
1 255 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Aeromonas phage PZL-Ah8
[NCBI] 		2870529 Autographiviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ851152 [NCBI]
CDS location
range 22763 -> 23077
strand -
CDS
ATGAAGGTGAAGTTCAAGAAGCGAGAGCAGACCACTAAGGTAATCCTTGTGTCTGCACAGGATGACAAGGGCTCACGTCAGCTCAACATGGAGGCCCGCTCCGGTGGGTCTCTACATCATGGCTACCACTATGTCATTCGCTCTGATGGCACTGTGGAGGAAGGGCGAGCGCATGATGAGGTCAGTTCGTTCCGCGACAAGACCGCTATCTACGTTCGTGAGAACCACATGTGTCCACCTCCTCCGCCCAGCTTAGTGTTTGATGAGTGGGCTGGCCTTGAGTTCGTCAAAATGAAGGAGGAAGACATTGGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
A0A8A6C5V8
Method AlphaFoldv2
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
PDB ID
A0AAE8XD15
Method SMR
Resolution –
Chain position –
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (48uUY) rather than this protein.
PDB ID
48uUY
Method AlphaFoldv2
Resolution 83.42
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50