Protein

Protein accession
A0AAE7Y990 [UniProt]
Representative
4BZyV
Source
UniProt (cluster: phalp2_2279)
Protein name
Glycoside hydrolase family 108 protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKDNYQHCLEMILHHEGGYVNHPKDPGGETNLGITKRVYEDFGGTKDMKDLLVEDAAPIYEKNYWNRLKCNDIPNGLDLCVFDFGVNAGTGRSAKYLQTMIGTVADGGIGPNTLRKLGEYIDKHGLETTIKNFQEARQSYYEKLKTFETFGRGWTRRVTETTEEALKMC
Physico‐chemical
properties
protein length:169 AA
molecular weight:19208,5 Da
isoelectric point:5,97
hydropathy:-0,69
Representative Protein Details
Accession
4BZyV
Protein name
4BZyV
Sequence length
259 AA
Molecular weight
28595,69470 Da
Isoelectric point
4,67980
Sequence
MTDDELDNKPVSDAEFAEFMRPTSFTNEIPIEEVEWGLGLTEEEAYTLLDGACDLSCVSSDLPIERVEFTPVHFADTEPRTLTNQEIDELFAELNPPENTMDFEKAFAILLKHEGGFSNHKDDTGGATMWGVTEKVARAHGYTGEMRNLPIEFAKRVYKLTYWDAVRADALPAAVRYSVFDAAVNSGVGRATKWLQTAVGTKPDGIIGPQTLAAVGKQDPEKLNAKYNGVRLTFLTELPNWGSFSKGWARRVASNLVGA
Other Proteins in cluster: phalp2_2279
Total (incl. this protein): 20 Avg length: 170,8 Avg pI: 7,14
Protein ID Length (AA) pI
4BZyV 259 4,67980
Q775E1 163 8,02530
M1IDQ5 170 5,43394
A0A0M3LSH2 177 7,78232
K4NWI7 159 6,74425
A0A1V0DYF6 173 5,03834
G3ENC1 164 9,32769
A0A4P2VP99 159 5,71814
A0A7S6ILM4 170 5,42059
A0A6G5YF88 156 8,92405
A0A6J5MWZ2 158 8,92321
A0A6J5RUV2 159 8,73303
A0A8S5LFE0 167 6,97206
A0A8S5QI10 167 9,09612
A0AAE7Y8Y4 169 5,96590
A0AAE7YC44 169 5,96590
A0AAE8CB68 169 5,96590
A0AAE9FNN3 169 9,01173
A0AAE9JXQ4 169 9,01173
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17741
7qInl
 84 38,6% 181 2.404E-52
2 phalp2_12384
8ztAB
 22 26,2% 194 5.613E-33
3 phalp2_20399
37U0b
 4 34,7% 167 3.749E-30
4 phalp2_34040
7YRCZ
 1 30,1% 159 9.742E-28
5 phalp2_34912
4ndwJ
 921 34,9% 166 1.326E-27
6 phalp2_38682
IrRH
 2 30,0% 160 1.326E-27
7 phalp2_8688
88cVm
 11 29,5% 176 3.344E-27
8 phalp2_28296
11n7u
 4 29,1% 158 1.564E-22
9 phalp2_15555
7nVqq
 50 29,6% 199 2.687E-18
10 phalp2_28216
md6G
 23 26,6% 184 2.064E-15

Domains

Domains [InterPro]
Disordered region
GH108
Representative sequence (used for alignment): 4BZyV (259 AA)
Member sequence: A0AAE7Y990 (169 AA)
1 259 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05838|PF09374

Taxonomy

  Name Taxonomy ID Lineage
Phage Methylophilales phage Melnitz-3 EXVC039M
[NCBI] 		2832341 Kyanoviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ577098 [NCBI]
CDS location
range 38005 -> 38514
strand +
CDS
ATGAAAGATAACTATCAACATTGTTTGGAGATGATTCTCCATCACGAGGGTGGTTATGTCAACCATCCAAAAGACCCAGGCGGTGAAACTAATCTTGGCATTACCAAGAGAGTTTATGAAGATTTCGGTGGTACAAAAGACATGAAAGACTTACTTGTAGAGGATGCCGCACCTATCTACGAAAAAAATTATTGGAATCGTCTAAAATGTAATGACATTCCAAACGGGCTAGACCTTTGCGTATTCGATTTCGGAGTAAACGCTGGTACAGGACGAAGTGCAAAATATTTGCAAACAATGATTGGAACTGTTGCCGATGGTGGCATTGGGCCAAATACACTAAGGAAACTTGGTGAGTATATTGATAAACATGGTCTTGAAACAACTATCAAGAACTTTCAAGAAGCACGTCAATCATACTATGAAAAATTAAAAACATTTGAAACATTCGGTAGGGGTTGGACTCGTAGAGTTACAGAAACTACAGAAGAAGCTCTAAAAATGTGTTGA

Gene Ontology

Description Category Evidence (source)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4BZyV) rather than this protein.
PDB ID
4BZyV
Method AlphaFoldv2
Resolution 72.19
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50