Protein

Protein accession
A0AAE7Y5K8 [UniProt]
Representative
4UUVw
Source
UniProt (cluster: phalp2_17467)
Protein name
Lysozyme
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKTHIVVHCSDTPHSMKVTVDHLYQWHVVENGWSAIGYAYFIDQAGLTHKCRDLDGDGDVEDEIGAHARGFNRGSIGVCLEGRGTYTAEQLAALEFLLDDIRSRHGIPLDNVIGHRDVDPHKECPMMDVHKFVRRRG
Physico‐chemical
properties
protein length:138 AA
molecular weight:15561,4 Da
isoelectric point:6,09
hydropathy:-0,45
Representative Protein Details
Accession
4UUVw
Protein name
4UUVw
Sequence length
219 AA
Molecular weight
25272,70350 Da
Isoelectric point
8,63001
Sequence
MKKIENIIIHCSDSEFGSAAMIRQWHLQNGWKDIGYHFVILNGLIVPNTQSGQKQLYVPFMDGMIEVGRHLDGDDFVTSNEVGSHALGYNDKSAGVCLVGKKTFTKKQFDSLIMWLDYFLPLWKLPIEVVKGHYEVSPNRTCPNFDMKRFRMEYAARSTYVNDGGVYVPQAFDHTKPIPQGHEHLYTKQQLQQRINHLLKTSGWTQEAVYLVAYRDKMK
Other Proteins in cluster: phalp2_17467
Total (incl. this protein): 16 Avg length: 166,5 Avg pI: 7,79
Protein ID Length (AA) pI
4UUVw 219 8,63001
2sOCJ 152 9,58563
3e4gW 186 9,20346
3eK7d 157 8,56174
4BEe4 165 9,35064
4Mukf 195 9,25226
4XgRA 220 7,68903
4flwP 177 8,75411
7ZW1Z 188 8,89259
pHHz 177 8,86706
A0A9P0YD53 138 6,02075
A0AAE7Y624 138 5,95118
A0AAE7Y6F8 138 5,95118
A0AAE7Y741 138 5,95118
A0AAE7YBM3 138 5,95118
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_24952
kjdf
 441 46,0% 152 6.791E-41
2 phalp2_20530
4iTZt
 5 39,2% 153 2.266E-34
3 phalp2_28564
7Z48s
 97 35,6% 160 1.936E-25
4 phalp2_3887
6RreM
 7260 36,0% 161 3.161E-24
5 phalp2_2237
4n15b
 512 34,1% 173 5.876E-24
6 phalp2_35354
7vHgi
 29 35,0% 157 2.030E-23
7 phalp2_33675
10JhP
 15 33,3% 144 3.772E-23
8 phalp2_23766
13ajC
 287 33,1% 160 3.772E-23
9 phalp2_25442
2RRxP
 189 32,4% 148 7.007E-23
10 phalp2_5171
285Oe
 13 32,7% 159 7.007E-23

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 4UUVw (219 AA)
Member sequence: A0AAE7Y5K8 (138 AA)
1 219 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage 19E33.1
[NCBI] 		2859308 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW824414 [NCBI]
CDS location
range 26580 -> 26996
strand -
CDS
ATGAAGAAGACGCATATTGTTGTGCATTGCTCTGACACGCCACATTCGATGAAGGTGACAGTTGATCACCTTTATCAATGGCATGTTGTTGAGAATGGTTGGTCGGCCATCGGTTATGCCTACTTCATAGACCAAGCCGGGCTAACTCATAAGTGTCGAGATCTAGATGGTGACGGCGATGTTGAGGATGAGATTGGCGCTCATGCTCGTGGATTTAACAGAGGCTCAATCGGTGTGTGTTTGGAGGGGCGAGGTACTTATACTGCTGAGCAACTAGCCGCACTCGAATTTTTGTTAGATGATATCCGCAGTCGACATGGAATCCCGCTTGATAATGTCATTGGTCACCGGGATGTCGACCCACATAAAGAGTGTCCTATGATGGACGTTCACAAATTTGTTAGACGAAGAGGCTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4UUVw) rather than this protein.
PDB ID
4UUVw
Method AlphaFoldv2
Resolution 89.45
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50