Protein

Protein accession
A0AAE7VA02 [UniProt]
Representative
1QZtJ
Source
UniProt (cluster: phalp2_37189)
Protein name
Secreted cell wall DL-endopeptidase
Lysin probability
100%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MITEKTSYELTYDTEKQKQLKQNDFEEALISFSTKNSMEDDSPVFSLVILAKEKWDKIINSNDLIRIRVIPDSTKGRPDNPYIMVGLISDIRKEGEFSEGSLFYRITGRAMTKALIDFEVGVIQEVSTVLVDGWLPDRQDDSGLKFSGNTAAGIGNELMEKFVYKYAKYNFANKKGLKDYLDHNFTSWEKDESLGDVTPFINYEGSIRQFLEDIAAKPFNELFFEFTASGKCTALMRPTPFDPDYWYQLPKYRFTSDIVVEESVGKNDEELYSVFVVQAPNIAEFTSMDLGVYPKFHPDLIKKKGYKRLDAQNRYLLSTALNDTTNASANPQDGAAPLPTYEEVLKFITDNGYQEPEILRTQKNTIYSELISKFPSISDSLANNILDSLKEGKFTREEYNNLTTSTGDAERDKEINKEKSVANAKLERFTQRLFNWYCENGNFYNGDIRVLGSPAYRLGSRVLYEDLEQKTTWEFYVESVQHEFSFTNGYTTVIGVTRGLPNSGEDRFSNLWGKSKDFKGGYLGESSLQDLLKEAKKANAPSEDGSGSWGDGAGSGGAMGALETAREMTGRNSVYVFGGGRSGSNPFLTTPIRIDCSAFVWWCFYLNGITLKGGKTGMTTDTIKTDSQLMTVSSRGSSKSAAKSKLQLGDLVYFDTYKGDGHIGIYSGNGKFIGSQSKSGIKEESMTSGYWWQKFNGRVLRYKG
Physico‐chemical
properties
protein length:704 AA
molecular weight:79147,6 Da
isoelectric point:5,30
hydropathy:-0,55
Representative Protein Details
Accession
1QZtJ
Protein name
1QZtJ
Sequence length
816 AA
Molecular weight
92275,75800 Da
Isoelectric point
4,56851
Sequence
LAEVKLRYPKFDLKFYTEDDEYHITYDARKDFSNEFTGESVIQLSTKNAMEEDTATFSLVLAGDVYWDRILQANDAVVLKIDPNEGGEKPQNPVLLVGLVSEVRQEADHGENSKMYRITGQSFAKAFTNFEIGVIQEVATQLTDIGWLPNSTEDGGFEMTQKTAAQMVESIVEHFLPYIKYNYSHTKKGIEEFLTWKLDSWVQEERLADETNFINYEGSLKQMLEDATARPFNELFFEATEDEQCELVLRRTPFDPEDWNHLTTYTITSKELISESVGLNDAESFSIFNISQKNNMLGASDVDLSAYPQYFKPLLDKFGYKELQVENLYLDTAVAEDSEEDDSEETEDDNDDTEEAESEDDSNEDEGQSFATMYNLVTNYLANYGRKKIRVVKDKVTKQIQNVDKRITKAMAQDIMDFYMEGKEKWSREAFSKLTGFSLSEEDGQKDKPDADYQDVRTTMDKSSNTNVTDLKNELVEKYNISEDQAVNVASEYLAEKLNKERFKEIMDDRSAEGMERIGTSKQVLIDFKKRLANWYCENPNFYSGDITVQGSPEYRLGGRLIVQDEQNGEIWEYYIESVQHSYSYTEGYTTTLGVTRGLQNAGRGRFTNLWGTSEDFKGGYMGEMSMEELLELQAKEDEKNQQEEDNGDDDSGDASSIPGSSIAVKAANFGKSMSKEESSHSSYYSWGGGRGSDPFKSEPYAMDCSSFVWWCFEKAGQSLAGGKGGMTTWTIKGDKNLKTVNPQGAKAGAKAKMKVGDIIMFYPSNGHIGIYLGGDKWVGCNGKPPTDHSSTAGIHVKSLSGFWWGQFNGHVLRLP
Other Proteins in cluster: phalp2_37189
Total (incl. this protein): 98 Avg length: 765,8 Avg pI: 5,54
Protein ID Length (AA) pI
1QZtJ 816 4,56851
13cMn 814 6,61949
1QZCn 762 4,21009
1QZtL 1064 4,58392
1QZyd 815 4,24294
1RhpQ 811 7,02049
1ceYF 839 4,80343
1dOHK 805 8,33114
22cZ2 840 4,79559
22d0R 1095 4,97713
2UY02 765 5,82909
2UYD4 724 5,31077
2WCeQ 745 5,98881
2YkLJ 717 5,08467
2ZNuG 752 4,99179
34frH 755 5,63737
3LlsY 763 4,76773
3Lmed 746 5,17970
3Lvl7 768 4,79178
3lUxh 839 4,88209
3mvqT 839 4,85663
4Uao1 729 4,41198
66tpJ 838 4,80974
6YhSO 882 5,94879
6mKRq 838 4,80974
7Ak5G 746 5,98483
7Al7i 704 5,35721
7Anob 795 5,14804
7AonL 718 5,36221
7C6rL 872 5,28167
7C7IY 723 5,13338
7Fs3k 783 8,47819
7PbWP 810 7,16645
7Pf93 748 5,86524
7PnHk 714 5,33391
7PnNc 725 5,21614
7PoPe 725 5,21392
7Pq28 730 5,18095
7PqLW 725 5,26769
7Pqdg 719 5,51460
7Pqrp 756 5,52966
7PqvG 761 5,86944
7aWdm 757 5,77492
7aZUA 810 6,31745
7b2SN 718 5,51795
7jCML 1061 5,24063
7jL5T 725 5,27065
7sp1X 800 5,97920
7zVWV 755 5,12042
8Ha2K 746 5,66170
8Ha2Z 670 5,47703
8Ha30 725 5,22012
8Ha34 763 4,80650
8Ha3F 714 5,54012
8Ha3J 719 5,66067
8Ha3k 757 5,67744
8Ha3t 725 5,32226
8Ha43 732 7,96264
8Ha44 798 6,35741
8Ha49 808 6,19996
8Ha4g 808 6,09606
8Ha4n 807 6,36104
8Ha4x 868 5,94538
8Ha4z 810 7,18674
8L9Az 704 4,89920
8LLq4 804 6,53901
8LLu2 746 5,18743
8LSnD 744 5,86518
8LZlx 754 5,99472
8M2iJ 714 5,46396
8M7gj 756 5,40689
8M7p4 755 5,63737
8M9HA 795 5,14804
8ME09 839 4,80974
8MafE 756 5,45890
8Ml4H 746 5,86518
8MrbE 839 4,78149
8MzjG 811 6,88061
8a8tk 1054 5,25894
8tL22 842 4,82679
PGGD 747 5,00168
gmH 795 5,14804
ih6 767 4,85311
nXaK 637 4,96150
A0A7T7ZB14 667 5,50971
A0A7T7ZBL4 667 5,50971
A0A7T8C599 686 5,33163
A0A7U3TFR1 686 5,33163
A0A068CCA3 276 5,98182
A0AAE7SEY5 718 5,36596
A0AAE7WZ18 663 6,34752
A0AAE8BP69 663 6,34752
A0AAN0LHZ2 704 5,35721
A0AAX4Q4W2 704 5,35721
A0AAX4Q5I2 704 5,35721
A0AAX4Q695 704 5,35721
A0AAX4Q8A9 704 5,35721
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33582
8LHfr
 135 40,3% 516 1.514E-211
2 phalp2_11026
4Sv8d
 15 25,7% 1054 9.975E-158
3 phalp2_25144
1Emml
 5 25,4% 973 7.431E-119
4 phalp2_28907
5tXTi
 21 26,6% 881 1.595E-117
5 phalp2_5245
7YnjZ
 6 21,1% 916 4.279E-94
6 phalp2_1764
2LOtm
 25 21,9% 820 5.723E-72
7 phalp2_11331
7jPy7
 2 22,7% 641 1.018E-48

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BspH_Mawwa
[NCBI] 		2836115 Herelleviridae > Siophivirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MW749002 [NCBI]
CDS location
range 143045 -> 145159
strand -
CDS
TTGATTACTGAGAAGACATCATATGAGCTTACATACGATACAGAAAAACAAAAGCAGTTAAAGCAGAATGACTTCGAAGAGGCATTAATCTCTTTCAGTACTAAAAACTCCATGGAAGATGACAGTCCTGTCTTCTCTTTAGTTATACTTGCTAAGGAAAAGTGGGATAAGATAATAAACTCTAACGATTTAATAAGGATTAGAGTTATTCCTGACTCAACTAAAGGTAGACCGGATAACCCCTACATTATGGTTGGCTTGATTTCTGACATTCGTAAAGAGGGGGAGTTTTCAGAAGGATCGTTATTCTACCGTATAACTGGTCGAGCTATGACAAAAGCGCTAATAGATTTCGAGGTAGGAGTCATTCAAGAAGTATCTACAGTACTTGTAGACGGATGGTTACCTGATAGGCAAGACGATAGTGGACTTAAATTTTCTGGGAATACGGCTGCGGGAATTGGTAATGAGCTTATGGAGAAGTTTGTTTACAAGTATGCTAAGTACAATTTTGCAAATAAAAAAGGACTAAAAGATTACTTAGATCATAACTTTACAAGTTGGGAAAAGGATGAATCTCTAGGAGATGTTACCCCATTCATTAACTACGAGGGAAGTATTAGACAGTTCCTTGAAGATATAGCAGCTAAGCCATTTAATGAACTATTTTTCGAGTTTACGGCCAGCGGTAAGTGTACTGCTCTCATGAGACCGACACCGTTTGACCCGGACTACTGGTACCAACTTCCAAAGTATAGGTTTACTTCTGATATTGTAGTCGAGGAGTCTGTAGGTAAGAATGACGAGGAACTGTATTCAGTGTTTGTTGTTCAAGCGCCTAACATAGCGGAGTTTACTAGTATGGACTTAGGTGTGTACCCTAAATTCCACCCAGATTTAATCAAGAAAAAAGGATATAAACGGCTGGATGCACAGAATAGATATTTACTATCGACAGCACTTAATGATACAACCAACGCTTCTGCCAATCCGCAGGATGGTGCAGCCCCTCTACCAACTTACGAGGAAGTTTTAAAATTTATTACGGACAATGGGTACCAAGAACCTGAAATTCTTAGGACACAAAAAAACACAATATATTCAGAACTGATCTCTAAGTTTCCATCTATTTCTGATAGCTTGGCAAATAACATCCTAGATAGTCTTAAAGAAGGCAAGTTTACCCGGGAGGAATACAACAACCTTACAACGTCTACAGGAGACGCAGAAAGGGACAAAGAAATTAACAAAGAAAAAAGTGTAGCTAACGCAAAGCTAGAAAGATTTACACAGAGACTATTCAACTGGTACTGTGAGAACGGAAACTTTTATAATGGAGATATTCGTGTCCTTGGAAGTCCAGCTTACAGACTCGGTTCCCGGGTACTCTATGAAGATTTAGAGCAGAAAACAACTTGGGAGTTCTATGTAGAGTCTGTTCAGCACGAGTTTAGTTTCACCAACGGGTATACAACTGTTATCGGAGTAACCCGTGGATTACCTAACTCCGGAGAAGACCGATTTAGTAACCTTTGGGGTAAATCTAAAGACTTTAAAGGAGGATACCTTGGAGAGAGCTCTTTACAAGACCTCTTAAAAGAAGCTAAAAAAGCTAATGCCCCTTCTGAAGACGGAAGCGGTTCATGGGGAGATGGAGCCGGAAGTGGAGGAGCAATGGGAGCTCTCGAAACAGCCAGAGAGATGACAGGGAGAAACTCTGTATATGTCTTTGGTGGAGGAAGGTCGGGAAGCAACCCATTCCTAACAACACCTATTAGAATTGACTGTTCCGCTTTTGTATGGTGGTGTTTCTACTTAAATGGCATAACCCTTAAAGGCGGAAAGACAGGAATGACAACAGACACAATTAAAACCGATTCTCAGCTTATGACAGTAAGTTCTAGAGGATCGTCTAAGTCAGCAGCTAAAAGCAAACTCCAATTAGGAGACCTTGTTTATTTTGATACATATAAAGGTGACGGTCATATTGGAATTTATAGCGGGAACGGTAAGTTTATCGGCTCCCAAAGTAAGTCAGGTATTAAAGAAGAGAGTATGACTAGCGGTTACTGGTGGCAGAAATTTAACGGCCGTGTACTTCGATATAAAGGCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1QZtJ) rather than this protein.
PDB ID
1QZtJ
Method AlphaFoldv2
Resolution 81.61
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50