Protein

Protein accession
A0AAE7RIE1 [UniProt]
Representative
8rpRb
Source
UniProt (cluster: phalp2_5277)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
METRGLPWLVEGYKLLGIHEATKDGGAEVDKLWKDFKMGGLVGSPTTIPWCSGFVGGTLTRAGLPTTSTSQYNKASSQYWLGYGTKLSKPAFGCIVVFKYPNGNGHVGYVVGKTSSGLLLVLGGNQSDMVCVKAFKTGLIQGYVFPEGNYTIDYDLPIGDAELVGSTR
Physico‐chemical
properties
protein length:168 AA
molecular weight:17940,3 Da
isoelectric point:8,37
hydropathy:-0,05
Representative Protein Details
Accession
8rpRb
Protein name
8rpRb
Sequence length
94 AA
Molecular weight
10018,18370 Da
Isoelectric point
6,53969
Sequence
MTGKQSYLEWGVKLDKPVDGCIVVFTRTGGGHVGFVVGQDSKGDLLVLGGNQQDQVKVSAFGVDRVTGYRWPTGVPVETKLSVGNSVDFSTKES
Other Proteins in cluster: phalp2_5277
Total (incl. this protein): 18 Avg length: 154,9 Avg pI: 8,26
Protein ID Length (AA) pI
8rpRb 94 6,53969
6Dt5d 66 5,61975
8rCvh 101 9,42065
xo6w 101 9,42065
A0A222YWL8 161 9,02843
A0A1J0MEU0 158 8,51610
A0A3B8DJ19 168 8,37962
X2CST8 158 8,51597
A0A1U9ZAE8 158 8,99149
A0A7G9UUR1 168 8,36943
A0A2I7S7W9 229 8,77674
A0A2I7SB14 229 8,77674
A0A6B9SPC0 158 7,68136
M4MHS6 189 6,10231
A0A9X9JSI4 159 8,49018
A0AAF0APW1 165 9,20075
A0AAF0GW40 159 8,47471
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_556
H4lq
 5 47,3% 93 4.528E-29
2 phalp2_26508
40TJu
 12 53,3% 75 7.190E-27
3 phalp2_768
1YX1Z
 1 43,2% 81 2.659E-19
4 phalp2_39164
35aH9
 5 33,7% 86 1.009E-15
5 phalp2_23434
6ADve
 14 41,6% 72 9.279E-15
6 phalp2_36357
qs4Q
 1 39,1% 74 9.916E-12
7 phalp2_13927
8wgea
 14 39,1% 74 4.090E-09
8 phalp2_31888
4I8UQ
 5 32,8% 67 2.513E-07

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 8rpRb (94 AA)
Member sequence: A0AAE7RIE1 (168 AA)
1 94 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Proteus phage VTCCBPA139
[NCBI] 		2704027 Demerecviridae > Novosibvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MN935203 [NCBI]
CDS location
range 21058 -> 21564
strand -
CDS
ATGGAGACGAGAGGATTACCTTGGTTAGTTGAGGGGTATAAACTACTAGGGATACATGAAGCAACTAAAGATGGTGGTGCTGAGGTAGATAAACTGTGGAAAGACTTTAAGATGGGTGGTCTAGTAGGCAGTCCAACAACTATACCATGGTGCTCTGGGTTTGTTGGCGGTACGCTAACCAGAGCAGGGCTACCTACTACCAGCACCAGTCAATACAATAAAGCTAGTTCTCAGTACTGGCTTGGTTATGGAACCAAATTGAGTAAGCCAGCTTTTGGGTGTATAGTAGTGTTTAAGTACCCTAACGGTAACGGTCATGTTGGGTATGTAGTAGGTAAAACCTCAAGTGGGTTATTATTAGTATTAGGTGGTAATCAAAGCGATATGGTATGCGTAAAAGCATTCAAAACCGGACTAATACAAGGATACGTATTCCCAGAAGGTAACTACACTATAGATTATGACCTACCAATAGGTGATGCAGAGTTAGTGGGATCAACTAGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8rpRb) rather than this protein.
PDB ID
8rpRb
Method AlphaFoldv2
Resolution 71.98
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50