Protein

Protein accession
A0AAD1VIB2 [UniProt]
Representative
fryy
Source
UniProt (cluster: phalp2_26156)
Protein name
Cell wall-binding endopeptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 91% (predicted by ML model)
Protein sequence
MAWDSEAQRIAVNVIAHVEGSGAWDAINYRDPITVGLMQWYGTRAASILKDMKDNGTWSTDAELTSLSSDLDTQAVSSRWWTTRYLSGSEGKALKPVLRANKPIQSATVSSDIDDYKTAAERIGMSPDDNTKAVQFFCCMYHQTPARAIRIVNAAGAKSSLARIYSYCMADPVFKQYKTRYTTARDMIDNGNPPDIIDLNDDDRPIPDGDGGDEASAGNNGERELGDIRYLAVVGDTIHVTLKDGVTLIAVPTVGQRFILPRTTLGSGASPEIPDDEENTGEPDPPPYSGDISQAQQTLLDYADSVLGDWVYTNDYRRVNAHENNAGDCSAFTREAYKRVGVKLGLLTSNQYTQGTRIYSGSPANVDMSKLQVGDLIYMQWSNPAWNSGKVTDHVEMLYSAVGQGVLVGHPGPGRGPRKWTTTSAYTYLQGARKIWVQRHLN
Physico‐chemical
properties
protein length:442 AA
molecular weight:48494,4 Da
isoelectric point:5,19
hydropathy:-0,49
Representative Protein Details
Accession
fryy
Protein name
fryy
Sequence length
431 AA
Molecular weight
44986,88240 Da
Isoelectric point
6,02797
Sequence
MGRPASGQCIVFGMTYDATAKKLAVKVIGTVESDLNYGAINYSDPITVGVAQWFGTRAAALLNSMRTGNPGAWYGVAESLNSQLIGIASSDAFWNTRYLTRAEGDSLAGVLARNQAIQNATLTTDMDAYKAVAVSYGFDPDANTATVIYFFAMHHQSPASALRVVGTLSTTATLDQIHAATLADSVLGQYGARYRTVYDLVSVADLTGVDPAPEPPAAKPNGNVRYITLVGDQLHVRFQDNEVVTYLPDGRGHWIGRTAATPPTPVQPAPPAGTGAWVHPLPGATLTSPYGPRATPAGTADINGGFHFGSDLANSGAAGNILAPCDLVITVARAYSTSNPDKGTAGNYVKGHTTDGKYTFSFFHMANAPAVTVGSTVSAGTVLGVEGATGNVTGRHLHLECYNGAINDPWAPPYGNPIDPLPVLRAHGVII
Other Proteins in cluster: phalp2_26156
Total (incl. this protein): 37 Avg length: 422,3 Avg pI: 5,23
Protein ID Length (AA) pI
fryy 431 6,02797
1hM6e 425 4,66849
1hT5P 419 4,98469
1hUhr 420 4,79286
1hUhx 420 4,61381
1jY3V 429 4,66162
1jlSJ 417 5,90628
1jmLV 418 5,96761
1jmVk 418 5,78873
1jmdH 421 5,97312
1jn1P 417 6,02677
1jnlj 418 4,87465
1jqAL 417 5,78663
1jqos 418 4,87914
3Pttp 420 4,51611
3V3yb 424 4,76114
4XR5M 422 4,69328
4XWAe 419 4,80297
4XWI4 419 4,80320
4YhGO 420 4,95246
4YhLY 420 4,91409
59NCj 420 5,09808
59Nwb 420 4,91409
5Cjcw 418 5,34459
6Cc17 425 5,29207
6DVGW 424 5,13503
6Ko7c 424 5,36267
6W4tO 420 4,99986
7Z7rm 423 4,63314
7Z7yQ 424 5,03073
frRh 423 4,78922
ft7z 415 4,55004
fvSM 424 4,28585
fvh2 424 4,30029
A6XAE0 433 8,67939
A0A8S5N0B2 434 7,66050
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_32444
11uoj
 18 23,9% 443 2.031E-42

Domains

Domains [InterPro]
Unannotated
Unannotated
PET_M23
Representative sequence (used for alignment): fryy (431 AA)
Member sequence: A0AAD1VIB2 (442 AA)
1 431 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Glutamicibacter phage Voltaire
[NCBI] 		2891955 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OV696617 [NCBI]
CDS location
range 14561 -> 15889
strand +
CDS
ATGGCCTGGGATAGCGAAGCACAGCGCATTGCTGTGAACGTCATAGCACATGTAGAGGGGTCTGGCGCGTGGGATGCGATCAACTACCGCGACCCAATCACCGTTGGCTTGATGCAGTGGTATGGTACGCGCGCCGCGTCGATCCTGAAAGACATGAAAGACAACGGCACATGGTCTACTGATGCGGAGCTGACGAGTTTGTCTAGCGACCTGGACACACAGGCAGTGTCTAGCAGGTGGTGGACTACCCGCTACCTGTCAGGTTCAGAGGGCAAGGCGTTGAAGCCTGTGTTGCGTGCTAACAAGCCGATTCAGTCCGCTACGGTGTCTAGTGATATTGATGATTACAAGACTGCTGCAGAGCGTATCGGCATGTCTCCTGATGATAACACTAAGGCGGTGCAGTTCTTTTGCTGTATGTATCACCAGACACCAGCTAGGGCTATCAGGATTGTGAATGCTGCTGGTGCGAAGTCATCGCTTGCCAGGATTTACAGTTATTGCATGGCTGACCCTGTGTTCAAGCAGTACAAGACCAGGTATACGACGGCGCGGGATATGATCGACAACGGCAACCCGCCTGACATTATTGACTTGAATGATGATGACAGGCCAATCCCTGATGGTGACGGGGGTGATGAAGCATCAGCTGGCAATAATGGTGAGCGTGAGCTAGGGGACATACGTTATTTGGCGGTGGTGGGTGACACTATTCATGTGACGTTGAAAGACGGTGTGACACTCATAGCTGTTCCTACAGTGGGACAGCGATTCATTTTACCGCGCACTACTCTAGGTAGTGGCGCGTCACCTGAAATTCCTGATGATGAAGAAAACACTGGCGAACCTGACCCGCCACCGTATAGCGGTGACATTAGCCAGGCGCAACAAACGCTATTGGACTACGCTGATTCAGTGCTAGGGGATTGGGTTTACACTAACGATTATCGTCGTGTTAACGCTCATGAAAATAACGCTGGCGACTGTTCAGCATTCACACGCGAAGCGTATAAGCGTGTTGGCGTGAAACTGGGTTTGCTCACCAGCAACCAGTACACGCAGGGCACACGCATTTACAGTGGATCACCGGCCAACGTGGACATGTCCAAGTTGCAAGTAGGGGACTTGATCTACATGCAATGGTCTAACCCCGCCTGGAATAGTGGCAAAGTGACTGATCACGTGGAGATGCTCTACTCCGCAGTTGGGCAAGGTGTGCTGGTTGGACATCCTGGTCCTGGGCGCGGGCCGCGTAAGTGGACAACAACCAGCGCTTACACATATTTGCAGGGTGCACGTAAGATATGGGTGCAACGGCATTTGAACTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (fryy) rather than this protein.
PDB ID
fryy
Method AlphaFoldv2
Resolution 82.83
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50