Protein

Protein accession
A0AA96EU32 [UniProt]
Representative
7FwYi
Source
UniProt (cluster: phalp2_31943)
Protein name
C39 family peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTKLNVPYFSQRDNYRDSWRTCFSSSCAMLLKFLKPEAITGDDDYIRSVFRNGDTTSSAVQLRTLGQYGVKGRFVDNINTDILKQQIDRGFPVPVGILHKGTAWNPTGGGHWLVVIGYDDEGFIVNDPWGQISHSTGEYLSTNGESVKYSYDLMGSRWTVYGTSDGWAILVDGVTQ
Physico‐chemical
properties
protein length:176 AA
molecular weight:19678,7 Da
isoelectric point:5,52
hydropathy:-0,36
Representative Protein Details
Accession
7FwYi
Protein name
7FwYi
Sequence length
412 AA
Molecular weight
45390,30070 Da
Isoelectric point
5,78805
Sequence
MKTSTKGTDLIKEFEGCELTSYVCPAGVLTIGYGHTGVDVKPNQTITQEKASSLLVSDLKRFERTVNDNVTVEITQSMFDSLVSFTYNCGSDAFRNSTLLRLLNDKDYEGAASQFDRWINGANGPLPGLVRRREAEEKLFRSEGFPDGTSQDKPNIVTTITAVTDTVLKKEPVQSSELAENQMVTVKAGKEYQLVWQGDSSYGHTRISLAYGGGNWFIYDDHWKGAKTNPVPVTKGEGVVLDTRYFSQRDNYRDANRTCFSSSCAMLLETLKPGTLPGERGDDKYVQTVFTIGDTTEAWVQVKALERYGVSAAFVQNGSVSLVKSQIDKGIPVPIGILRHGPASAPSGGGHWICVIGYNDKGFVVNDPWGEIDHKSGQYISTDGNRLQYSYNLINARWTIANPNDGWCIIAK
Other Proteins in cluster: phalp2_31943
Total (incl. this protein): 314 Avg length: 400,8 Avg pI: 7,39
Protein ID Length (AA) pI
7FwYi 412 5,78805
10auc 389 8,43429
13T6g 410 5,85472
140i1 410 5,74968
145cp 412 9,03539
15ZCN 412 8,03058
15c13 414 7,03663
15lJT 415 8,75843
15qSr 412 6,82468
160vC 413 8,50301
1629M 414 7,77800
16374 412 7,66362
165O4 393 7,62929
18Pj9 415 8,08783
19CYx 411 7,04630
19W5Z 412 7,76963
1AjAL 415 5,81818
1BzNe 415 6,77955
1DRpI 284 6,16006
1FYS 410 5,92373
1GWQy 404 8,26119
1GXSV 404 7,96115
1JV3n 411 8,47993
1NQL4 408 7,06744
1PJbt 416 9,23498
1PNy8 412 8,40985
1PfCL 426 8,67263
1Qce9 407 7,07125
1Qyn3 428 8,46549
1RPt3 389 8,15739
1Rqn 382 4,83492
1TCiX 383 4,62575
1TIL4 386 6,56316
1TPlc 380 8,56561
1TuZ3 386 6,60864
1UVwf 381 8,00074
1WbWM 386 6,28994
1XRA1 414 8,51584
1aYAn 416 8,14605
1ars4 355 8,45040
1eADZ 412 8,45150
1h9sn 418 8,11272
1nseo 411 6,42777
1pdoD 415 8,47864
1tLck 411 6,41822
1wSni 411 7,12422
1xjyc 390 4,72249
1zlHZ 410 8,76804
1zrbL 413 6,73385
22LHW 414 8,58785
22Mb7 374 8,69558
26sV0 409 5,78208
27PJ6 414 8,94855
27RI7 412 7,17327
29L4P 416 8,14605
2GzhS 417 8,89446
2ImZj 412 7,12968
2IrrH 414 7,97798
2ItHd 415 6,17478
2JQFs 348 4,24021
2JVMl 361 5,52398
2Jqtq 417 8,90806
2K6if 410 5,77049
2K9VE 409 5,65516
2KFQQ 412 9,02159
2KFdX 412 9,09754
2KITJ 418 9,27328
2Kd30 411 6,64916
2Kgoc 410 7,55921
2OlBE 410 8,17119
2PIkk 379 5,09365
2R5eg 411 7,72302
2RFTc 387 4,80752
2RmYa 426 8,50888
2UPeg 412 8,27969
2W0yX 340 9,20662
2WYwv 393 8,31818
2cUph 416 8,09918
2d4qH 413 6,51957
2fGfE 363 4,80741
2gVDS 413 6,23930
2iREk 412 5,64033
2iYy9 412 6,33956
2ivj6 412 8,16075
2kRE9 409 5,93367
2nhzl 389 4,93234
2s4nI 342 4,89397
2s4wJ 344 4,69629
2s5bb 427 4,93058
2s6Ne 416 6,03951
2waeT 374 5,15202
2y72Z 421 5,17868
30TdL 412 7,76394
31Hwe 413 6,80990
31yCt 411 7,04624
36pD5 412 8,82825
37Jui 305 8,63298
3CERI 386 6,37014
3Gp9i 411 6,15927
3GsWi 386 7,18163
3I0AR 384 6,45693
3ICG5 413 5,85381
3QriH 413 6,39310
3Qs4j 408 7,05300
3SPdP 414 8,85533
3ScOy 420 8,88440
3U4v0 386 8,26622
3UkY4 410 5,78896
3VXnI 421 8,50436
3Y2Jc 393 8,54885
3Z544 410 7,98430
3cPgb 411 7,04630
3d9SD 416 8,14598
3dhPS 381 8,74986
3oa5B 423 5,93640
40A0t 381 7,99506
40swf 418 7,11575
42rwi 386 6,04343
45D1A 408 8,71305
45F2E 413 8,70963
45FFp 411 6,41822
45YjR 411 7,11683
45Zje 419 9,23550
46PIC 407 8,96099
46aA7 415 8,32914
46geY 415 8,05856
48gHY 414 8,63285
48k8 410 5,91219
49PjZ 393 7,59735
49Px1 410 5,78663
49fJ6 412 8,54917
49xua 386 9,00554
4A2MD 393 8,36801
4AeNK 372 9,03984
4AjZi 417 8,68294
4BS4J 412 7,23779
4BSqK 393 8,54311
4BVgN 416 8,96054
4BVpS 410 8,42165
4BVzt 393 8,06888
4C0Mn 426 8,35015
4DMIt 393 8,54311
4DPrO 410 9,25355
4DiT 334 8,61525
4GKR 349 4,92654
4GhKp 413 8,96725
4J4bM 415 8,25107
4OuAz 415 7,56410
4PXW2 409 6,24231
4Q9Tj 409 6,11232
4S9EZ 404 6,03769
4YBu0 410 8,30277
4YCJn 416 8,78519
4YE9U 413 8,31276
4Yy8M 412 8,95996
4cqi9 408 8,71305
4dLA1 413 6,61153
4efuh 411 6,41822
4fyxq 393 8,55072
4gqYS 410 5,43804
4jARE 395 5,45884
4ltZg 408 8,71305
4nWil 412 9,02733
4nkw8 369 6,78677
4ofYh 411 8,50423
4rAxj 393 8,57354
4sKjH 409 8,86655
4sNsE 410 6,09834
4sysZ 411 5,98881
4tnKG 411 6,57584
4zO7Z 393 8,34661
4zbGz 414 6,72612
4zz7K 386 9,12100
51DA3 412 8,96009
52RX2 412 8,75921
52XLL 412 8,48167
5381S 416 6,67912
57FyX 417 7,63032
57VGU 415 8,61705
57Y0T 418 9,09638
588Pn 393 8,54356
58CTa 412 8,56599
592H5 393 8,37330
596A7 412 7,64248
5ARSN 386 8,91412
5ApsG 409 5,78635
5BrFD 408 8,49895
5BsR0 412 8,22199
5Bwxc 416 8,52989
5Cn7Z 413 9,05679
5HAUk 414 7,03726
5HgRI 412 6,67895
5IaIW 411 6,53537
5Iafq 411 6,53617
5aUqr 410 5,82579
5c0jl 415 7,56592
5cCxg 346 7,65322
5dkGY 355 8,64722
5dqRh 393 8,54169
5dxn9 393 7,62907
5fs6m 393 8,54311
5kB1G 419 8,86319
5kxxi 355 8,46355
5l38M 416 7,71444
5lelR 393 8,07571
5lewi 379 5,42064
5lgow 393 8,35763
5lt8G 393 8,35563
5mhfQ 338 7,08466
5p5L2 415 5,68676
5sxiT 389 8,75063
5taHd 415 6,04377
5tcNn 415 5,79749
5uf6N 393 7,15656
5uiFr 393 8,35254
5vnLu 411 9,03094
5xoL4 411 6,73038
5zadW 412 7,79740
5zqe3 411 7,78129
5zvQ3 393 8,54311
5zyev 411 8,21729
6GML6 402 7,59525
6GSu5 355 8,65438
6GwBs 410 5,91497
6IBTB 411 6,57595
6Izi4 414 7,18265
6LA9q 410 6,42522
6MGyR 393 8,07288
6MeZy 370 8,79750
6vsS 411 6,73499
6xMLC 411 8,78590
6xb8b 393 8,54504
6xfOp 417 8,18550
6xgp1 393 7,15679
6xot1 412 8,49656
7DA9b 415 6,73527
7EFQ9 411 6,28522
7K9yB 415 7,56410
7SwVj 414 6,28960
7T9k2 385 8,40721
7V5RP 413 5,84910
7Xgv6 439 9,26748
7kkN 410 8,30271
7xzpr 421 4,99725
83DJ0 411 6,42146
83uge 389 8,12877
85FZh 410 5,79493
87bYE 393 8,69010
89gsJ 414 6,28812
89qlK 413 8,48238
8BAVd 414 6,28960
8CPXY 386 6,80558
8CzOF 386 6,57760
8Fs38 386 7,55284
8KX9Q 383 5,94618
8b5OP 416 8,96157
8cKOr 420 5,75622
8cSOP 415 6,29625
8dDLT 382 4,43159
8eQ4F 415 6,48899
8gA9e 409 5,79464
8h1w9 415 5,68313
8iiiv 386 6,33649
8jJl0 389 8,76739
8jsZR 384 7,09268
8my8G 410 8,50423
8qzjm 410 5,98153
8rbpR 413 8,19324
8sBAX 417 6,20525
8sNr1 383 7,12445
8soMA 409 6,28977
8uDnl 386 6,16097
8vdQM 389 8,42088
ACx4 372 6,51843
Anv6 417 9,01843
C8qY 408 6,76722
CcTr 412 7,23665
CkTS 413 6,61045
DjLp 412 8,70679
DzkD 407 8,02826
EBd 411 6,39191
EvNN 393 8,35763
EwSm 393 8,56728
FSSH 417 8,67301
G9YU 410 6,36110
GlYt 391 7,07989
HLm 410 5,93828
JdHR 412 8,84895
MJmT 411 6,57504
RYdP 413 5,92464
SA1e 408 8,56786
dPMz 413 8,58714
dV21 356 5,92088
gJYT 415 5,99750
gKvm 412 5,86029
io73 415 5,99750
ittL 413 6,79086
ivgp 394 5,82988
ix1R 412 8,17364
jXaM 355 8,87241
qLJ0 412 6,36059
qM1H 417 8,89594
qyiJ 393 8,54311
r8pd 411 6,20673
sw6G 390 9,14079
t8hO 393 8,07571
tbz1 411 6,64979
vELT 385 4,87266
xvIN 417 8,95564
xyJZ 415 9,02978
yBQa 386 5,57513
yTV5 382 5,42320
A0A6J5QVW4 145 5,76873
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_29201
77dZ
 15 50,0% 280 7.152E-128
2 phalp2_29834
276so
 38 57,0% 256 7.956E-103
3 phalp2_32013
5m77S
 660 30,0% 419 5.075E-99
4 phalp2_15789
45LhM
 112 29,7% 259 5.909E-79
5 phalp2_23836
1nEC9
 6 30,0% 373 1.076E-61
6 phalp2_5654
4rudF
 12 29,2% 263 7.492E-53

Domains

Domains [InterPro]
GH24
PET_C39
Representative sequence (used for alignment): 7FwYi (412 AA)
Member sequence: A0AA96EU32 (176 AA)
1 412 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00959, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-CREM2
[NCBI] 		3075959 Kyanoviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OR473000 [NCBI]
CDS location
range 135439 -> 135969
strand +
CDS
ATGACTAAACTAAACGTACCCTACTTTTCGCAAAGAGACAACTACAGAGACTCTTGGAGAACTTGTTTCTCTTCTTCCTGTGCTATGCTTCTGAAGTTTCTGAAACCAGAAGCTATCACTGGTGACGACGATTACATCCGCAGTGTCTTTCGTAACGGTGACACTACGAGCTCTGCTGTTCAGTTGCGAACCTTGGGTCAGTATGGAGTCAAGGGACGCTTTGTTGATAACATCAACACCGATATTCTGAAGCAGCAGATCGACCGTGGCTTTCCTGTACCTGTTGGTATTCTTCACAAGGGAACTGCCTGGAACCCAACTGGCGGTGGCCACTGGCTTGTTGTTATTGGATATGACGACGAAGGGTTTATTGTCAACGATCCCTGGGGTCAGATTAGCCACAGCACTGGTGAGTATCTATCCACTAATGGTGAATCTGTTAAATACTCCTACGACCTGATGGGCAGTCGCTGGACTGTATATGGAACATCTGACGGTTGGGCAATCCTAGTAGACGGTGTCACACAATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7FwYi) rather than this protein.
PDB ID
7FwYi
Method AlphaFoldv2
Resolution 88.16
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50