Protein

Protein accession
A0AA50EXV8 [UniProt]
Representative
2qjSX
Source
UniProt (cluster: phalp2_40218)
Protein name
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Lysin probability
67%
PhaLP type
VAL
Probability: 99% (predicted by ML model)
Protein sequence
MATVQKSTKINFYKFVQTKEVTSSPSGKISGGEIATVKAINTNTAAINNLGATVNSLAKIMSDYKKVAIMSYESELKNTKKFQAQYTTPKKREAVASGGGGGLSLKTPGFLDGLLNILGGLFKAAVVIPALEWISDPKNQKQVEDVITTIWNVVKFVADFTKFGVTKTIDGLYNLLSDETSPWEKIGGLVDGIVGLGGLLLGIRWLSNPTKLISDFGGTLKFFRKNLLSSKAGLLRRAGAAGLLVGGGYLLYKGITDFNEMRENAPAVPAPERAAGGKVPERSQGGWISGPQSGYPVSLDGGRSTSFIGHGTEYVARKANGGAFVVPFNTPATARQSNLTERRISEAKSMGYQLPGFAAGGNLDRQIYLHWTAGSYNHKAGPYHSTVQGNGKVYRAHPYNARTGHTYNRNTNNVGISAAAMGGRAWIDYPPKDIQINAMALEAANVAKKWGWKPSDVTIKRVMTHAEAGANKDGRRKHKNYGPVAWGGTGERWDWWHLKKNDKKGSGGDKLRQKIKHHLGDPNAKVVPEAGGISFDASTEGSSGGGTQMTNIPLTLSGKSKELVGGDGKFLLEVNRVADRLKIHPADLLGLMASESSLDPKAQNKSGATGLIQFMPSTAAGLGTSTAAIKKMTRVQQMVYVEKFLKQTLSGVPLVNGKVPAGNLYAAVYLPAFAKKSSSYVLAKRGGFNDDWGHHPAAWYTQNAGLDLNNDGAITVGELGKRIADKKKSFGIQGGTMSIPASEYSSVSPADHDDSNITPSNNFANAILGAVSKTAHLSGEQLFGREQATSMAPSATANNTNTGNGTRATNRGGRSTRGGSAKDSVISILGAAGLDDVLASKGLDRTDLMTIIDALSASKKAGGGQINIGDASASPDAQRRQGELKKTTDERNRARELINQRTQEMISSALDAVGKQNGVNAQMIALAQQGVQTALAASQTGAAQPQFIPTGGAGGGGGGGGGISGAALGGAIGGRTGAAIGGVAARVLNSTNNPLKGIFR
Physico‐chemical
properties
protein length:1000 AA
molecular weight:104881,3 Da
isoelectric point:9,84
hydropathy:-0,33
Representative Protein Details
Accession
2qjSX
Protein name
2qjSX
Sequence length
655 AA
Molecular weight
69469,70950 Da
Isoelectric point
9,63501
Sequence
MATIQKSAKINFYKFVAVKEPSSTAIKTEEGAALASNLNKNTEAINNLGSVVNSLAGLLSSLRTLAVKDLEAEEKNRTKFQANYTTTKKKEKKSSPKLGLQLQTPSFLEGLFNLLGGLFKIAVVTPVLKWISDPANQEKVVNIIDTISKVVKFIFDVAKFGVVNTIEGLYTLLSDESSPWEKIGGLVQGLTGLGTLLLGLRWLSNPTKILTDFGGVLKFLYNNLVRGKRGLLGRAGALGLVAGAAYGGYKLYQSLNDKEPTEVKEEKSQGGSVKNLPSRAQGGYINGPQSGYKVSLDGGRSTSFIGHGSEYVARKSNGGAFVIPLNTPGTKTQPHLTQKRVREAQSQGYKLPGRSLGGKVPEMALGGSMGGMMNAAGSWWNSLTGDSGKPKATTSEPVVKKGQEEKPVIGAGLQAVAAGGKWALDKGFTVAEHPNFRKNNHSGSGPNKGTGFNPRGGEAVGGHSNGSLHYKGLALDVTDWRPGAWKERTAQLGEDAYQMRDKLKLSQIITDGWGQWFRGGGKSGPGNTGHPTHLHLGFLDGISKGVTGGNGETGQMPANAGGYGAILDLIGKRESDSVGGYNAVNQGGADGGHTALGYSGDYRKAPFNPSGKELTSMTVQEVMDKQYDDRSMSDAQWKSSGKLHAVGRYQFIGST
Other Proteins in cluster: phalp2_40218
Total (incl. this protein): 23 Avg length: 844,1 Avg pI: 9,90
Protein ID Length (AA) pI
2qjSX 655 9,63501
2vq3U 892 10,00248
36ah0 925 9,69567
5A5vH 840 9,90397
5tbxc 840 9,89514
7CWth 923 9,78097
7XxPD 872 9,84305
7Z2J2 921 9,99229
7Z2tO 871 9,87999
81vbK 871 9,87999
8HquS 840 9,93414
8HquV 843 9,92351
8HquY 842 9,94330
8Hquy 840 9,90365
8Hqv0 840 9,93414
8HqvA 840 9,93414
8Hqvh 840 9,92351
8Hqvq 840 9,93414
8Hqvr 840 9,94330
8Hqvv 840 9,93414
pcDu 516 9,98211
A0A1D7T0X3 884 10,02156
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22625
1RWMF
 21 45,4% 576 2.104E-148
2 phalp2_9558
1gl5q
 24 39,3% 541 4.818E-142
3 phalp2_14898
8yFyU
 12 39,9% 551 4.282E-110
4 phalp2_26189
8Fvn9
 69 29,2% 768 9.008E-88
5 phalp2_1947
4upJo
 19 25,9% 795 4.097E-76
6 phalp2_31094
1UBAd
 39 27,0% 735 1.449E-48

Domains

Domains [InterPro]

No domain annotations available.

Taxonomy

  Name Taxonomy ID Lineage
Phage Synechococcus phage S-8S29
[NCBI] 		3038205 Kyanoviridae > Tefnutvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ504979 [NCBI]
CDS location
range 45525 -> 48527
strand +
CDS
ATGGCAACCGTACAAAAATCCACCAAGATTAATTTTTACAAGTTCGTTCAAACAAAGGAGGTTACTTCTTCACCGAGCGGCAAAATTTCTGGTGGCGAAATTGCTACAGTAAAAGCAATCAACACAAATACTGCTGCTATCAATAATCTTGGTGCAACTGTAAACTCCCTTGCCAAGATTATGAGCGACTATAAAAAAGTCGCTATAATGAGTTATGAGTCAGAATTAAAAAATACAAAGAAATTCCAAGCACAATACACAACACCTAAAAAGAGAGAAGCAGTTGCTTCTGGTGGTGGAGGAGGATTATCATTAAAAACTCCTGGATTCTTAGACGGTCTTCTTAATATTTTAGGTGGTCTATTCAAAGCTGCTGTAGTTATACCTGCTTTGGAATGGATTTCTGATCCCAAGAATCAGAAGCAAGTTGAAGATGTTATTACTACAATTTGGAATGTTGTAAAGTTTGTTGCTGACTTTACAAAATTTGGTGTTACAAAAACTATTGATGGACTATACAACTTACTGTCAGATGAAACTAGTCCTTGGGAAAAAATTGGCGGATTAGTAGATGGCATAGTTGGACTTGGTGGGTTATTATTGGGTATTCGTTGGTTAAGTAATCCAACTAAACTTATTAGTGATTTTGGCGGAACCTTAAAGTTTTTCCGTAAAAATCTATTAAGTTCTAAAGCGGGACTGTTGCGCCGTGCTGGTGCTGCAGGTTTACTTGTAGGTGGGGGATACTTACTTTATAAGGGGATTACAGATTTCAATGAAATGCGGGAGAATGCCCCCGCTGTTCCTGCGCCAGAAAGAGCAGCAGGAGGAAAAGTACCAGAAAGATCGCAAGGAGGTTGGATTAGTGGACCACAATCGGGATATCCCGTATCACTGGACGGGGGGAGATCAACCTCGTTCATCGGACATGGAACTGAGTATGTTGCTAGAAAGGCAAATGGGGGAGCTTTCGTCGTTCCTTTTAATACTCCTGCAACGGCTAGACAATCTAATCTGACAGAGAGGAGGATTAGTGAAGCAAAAAGTATGGGTTATCAACTGCCTGGATTTGCTGCAGGTGGTAATCTAGACAGACAAATTTATTTACACTGGACAGCGGGTAGTTACAACCATAAGGCTGGTCCATATCATTCTACAGTTCAAGGAAACGGTAAAGTTTATAGGGCTCATCCATATAATGCTAGAACTGGACACACTTATAATAGAAATACTAATAATGTAGGCATCTCTGCTGCTGCAATGGGAGGAAGAGCTTGGATTGACTATCCTCCTAAAGATATACAAATTAATGCAATGGCATTAGAAGCAGCAAACGTTGCTAAAAAGTGGGGTTGGAAACCAAGTGATGTTACTATCAAACGTGTTATGACTCACGCTGAAGCAGGAGCAAACAAAGATGGTAGAAGAAAGCATAAAAACTATGGTCCTGTTGCTTGGGGTGGAACTGGTGAACGTTGGGACTGGTGGCACTTAAAGAAGAATGATAAAAAAGGTTCGGGTGGTGATAAACTTCGTCAAAAAATTAAACATCACTTAGGTGATCCAAATGCCAAGGTAGTACCAGAAGCAGGCGGAATAAGTTTTGATGCTAGTACCGAAGGTAGTAGTGGTGGTGGAACTCAAATGACAAATATTCCACTCACTCTAAGTGGAAAATCAAAAGAACTTGTCGGTGGTGATGGTAAGTTTCTTTTGGAGGTTAATAGAGTTGCAGATAGACTGAAGATTCATCCAGCTGACTTATTAGGTTTGATGGCATCTGAGTCTAGTTTAGACCCTAAAGCACAGAATAAGAGTGGTGCTACTGGATTGATTCAGTTTATGCCTAGTACCGCTGCTGGATTGGGTACATCTACTGCTGCTATTAAAAAAATGACTAGAGTGCAGCAGATGGTATATGTTGAAAAATTCTTAAAACAGACTTTAAGTGGTGTACCATTGGTAAATGGTAAGGTTCCTGCAGGTAATTTATATGCTGCTGTATATTTGCCCGCATTTGCCAAGAAATCTTCAAGTTATGTTCTTGCTAAGAGAGGTGGATTTAATGATGATTGGGGACATCATCCTGCTGCTTGGTATACGCAGAACGCAGGTCTTGATTTGAATAACGATGGTGCAATTACTGTTGGAGAACTTGGTAAGAGAATTGCCGATAAGAAAAAATCTTTCGGTATTCAAGGAGGAACTATGTCTATTCCTGCTAGTGAATATAGTAGTGTAAGTCCTGCTGACCATGATGATTCTAATATTACACCCAGCAATAACTTTGCTAATGCTATCTTAGGAGCAGTAAGTAAGACTGCACATCTTTCTGGAGAACAGTTATTTGGTAGAGAGCAAGCAACATCAATGGCACCCAGTGCTACTGCTAATAATACAAATACTGGAAACGGTACAAGAGCAACAAATCGTGGTGGAAGAAGTACTCGTGGGGGTTCTGCCAAAGATTCTGTTATTTCTATTCTTGGGGCAGCAGGATTAGATGATGTTCTTGCATCAAAGGGGTTAGATAGAACTGACCTTATGACCATCATCGATGCTTTATCAGCAAGTAAAAAGGCTGGCGGTGGTCAAATTAACATTGGCGATGCTAGTGCTTCTCCCGACGCGCAAAGAAGACAGGGTGAGTTGAAAAAAACTACTGATGAAAGAAATAGAGCAAGAGAACTTATAAATCAAAGAACACAAGAGATGATAAGTTCGGCATTAGATGCTGTTGGTAAGCAAAACGGTGTAAATGCTCAAATGATTGCTTTGGCACAGCAAGGCGTTCAGACAGCACTAGCAGCGTCACAAACAGGCGCTGCACAACCTCAATTCATTCCCACTGGCGGCGCTGGAGGCGGCGGTGGTGGCGGTGGAGGTATCTCTGGTGCTGCCCTTGGTGGTGCTATTGGTGGTAGAACTGGTGCTGCTATTGGTGGTGTAGCGGCAAGAGTTCTAAATTCTACAAACAACCCTCTTAAAGGTATCTTCAGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2qjSX) rather than this protein.
PDB ID
2qjSX
Method AlphaFoldv2
Resolution 64.02
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50