Protein

Protein accession
A0AA49X551 [UniProt]
Representative
1QQ4D
Source
UniProt (cluster: phalp2_28453)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKILLDPGHGAGNRYNRGFKQVDNLPYCNEGECNFIYCRDYLKPALEKYGIEVSLTRKNIKDDPTLSERGKMGKGFDLLISCHSNAANGLASGVEIWDSTNTKESIKSLTDKICKSISKALGIPNRGTRYRKQANGTNYYGVLRSSQAKHSFIIEHCFHDNWSDVIKYRKNLNKVADVTAKTIADYFKLTDFIPTIVKHLPKTAIILPSITIAQAILESDWGRSELAQKAYNFFGIKASKEWTGKVYTKSTWEQRADGVKYEIKADFRKYDSISESIADHDNFFVSTEWRKKNYKRVLEAANYKEQAMALRACGYATDLNYSDKLIRLIEEHKLYKYDKEIKMDRISNWAKEAWDWAKEKGITDGSNPQGNCTREQLIVMLKRYDEMVRKEIEHEN
Physico‐chemical
properties
protein length:396 AA
molecular weight:45620,4 Da
isoelectric point:9,06
hydropathy:-0,67
Representative Protein Details
Accession
1QQ4D
Protein name
1QQ4D
Sequence length
598 AA
Molecular weight
66628,80950 Da
Isoelectric point
9,27379
Sequence
MAEVLKIVAGAGHGGGGTTPGKRTPDGEYEWDFNDIVADGFVDELSKYEGVQIRRVDDDDVSDGYEDIPLRDRVKEANSWGADYWFSFHHNALRGVWGDHTGTETFYWQGNPESKRVAQLVQDAMLEVYGLRDRGIKRGNHLYIIKNSNMPTILTEGGFMDSVIDIKVLRDSDKLYEAGKNVAKRFAEYKELKRKGKSDSKEKVKNLVSQDEFINFLKDGAIEGWKKYGILPSVSAAQAILESNWGKSELAVKANNLFGVKASDGWKGDKYLVETKEQDKNGNEFTVKAYFRKYESWSDSVEDHGTFFTSTPWREKNYATVIGEKDYKKQAKELQNSGYATDKQYANKLIRLIEQYDLYEWDKEAGISIPKKKSEKYQVVTSISGYKTAGDAKKRSNKATTVKSGSYYVYKKSNGMINVTSKDGVPGSWINPSDNKKKPTSSDGTYTVKSGDTLSGIAEKFNTTVDKLASLNGIKNKNLIRVGQKLKVSGSVSTTSSKTYTVKSGDTLSEIAQNHGTTVKQLQNANDIKNANLIRVGQKLTIPSGTSPKPSKEYHTVKSGDTVSELAQKYGSTTSQIKSWNNLKNANLIQVGQKLRVK
Other Proteins in cluster: phalp2_28453
Total (incl. this protein): 7 Avg length: 413,4 Avg pI: 9,44
Protein ID Length (AA) pI
1QQ4D 598 9,27379
A0A5J6T572 380 9,53031
A0A5J6T5D6 380 9,53031
A0A5J6T5S3 380 9,56390
A0A5J6T853 380 9,53044
A0A5J6TAQ8 380 9,56390
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_14098
7ooYL
 2 33,9% 433 2.156E-51
2 phalp2_10537
7Yl5a
 2 27,3% 450 2.002E-25
3 phalp2_21214
19jI2
 2 22,5% 478 2.104E-09

Domains

Domains [InterPro]
Ami3
GLUCO
Unannotated
LysM
LysM
LysM
Representative sequence (used for alignment): 1QQ4D (598 AA)
Member sequence: A0AA49X551 (396 AA)
1 598 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01520, PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Firmicutes phage HS18
[NCBI] 		3056396 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OQ890326 [NCBI]
CDS location
range 16019 -> 17209
strand +
CDS
ATGAAAATTTTATTAGACCCTGGACATGGAGCCGGGAATCGATATAACCGTGGTTTTAAACAAGTGGATAATCTTCCGTATTGCAACGAGGGCGAATGCAATTTTATCTATTGTAGAGATTACTTAAAGCCGGCACTTGAAAAGTATGGAATTGAAGTGTCGTTGACAAGAAAAAACATTAAAGATGACCCAACGCTTTCTGAGCGTGGGAAAATGGGAAAAGGATTTGATTTGCTTATATCATGCCACTCAAATGCCGCTAACGGACTCGCAAGCGGTGTGGAAATATGGGACAGTACAAACACAAAAGAGTCTATAAAGTCGCTCACGGATAAGATTTGTAAATCTATATCGAAAGCATTAGGCATACCAAATCGAGGAACGAGGTATAGAAAGCAAGCAAACGGAACAAATTATTATGGTGTACTTAGAAGCAGTCAGGCGAAACACAGCTTCATAATTGAGCATTGTTTCCATGACAATTGGAGTGACGTTATTAAGTACAGAAAAAACTTAAATAAAGTAGCAGATGTAACAGCAAAAACAATTGCGGACTACTTTAAATTAACTGATTTTATTCCCACAATTGTAAAACATCTACCTAAAACAGCTATTATCTTGCCGTCTATCACTATCGCTCAAGCAATCCTTGAGAGTGATTGGGGTAGGTCAGAATTGGCTCAAAAAGCGTATAATTTCTTCGGAATTAAAGCATCTAAAGAGTGGACCGGAAAGGTATATACAAAGAGCACTTGGGAACAAAGAGCAGATGGTGTGAAGTATGAAATTAAAGCAGATTTTAGGAAATACGATAGCATTTCTGAAAGTATAGCCGACCACGATAATTTTTTTGTATCAACTGAATGGAGAAAAAAGAATTACAAGAGAGTGCTGGAAGCTGCAAACTACAAAGAGCAAGCAATGGCACTTAGAGCGTGTGGGTATGCAACAGATTTAAACTATAGCGATAAGCTTATAAGACTGATTGAAGAGCATAAACTCTACAAGTATGATAAGGAGATTAAAATGGATAGAATATCAAATTGGGCAAAAGAAGCCTGGGATTGGGCAAAAGAAAAAGGAATTACAGACGGGTCAAACCCACAAGGGAATTGCACCCGTGAACAATTAATCGTGATGCTTAAAAGGTATGACGAAATGGTAAGAAAGGAGATAGAACATGAAAATTAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1QQ4D) rather than this protein.
PDB ID
1QQ4D
Method AlphaFoldv2
Resolution 81.50
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50