Protein

Protein accession
A0AA49E4U9 [UniProt]
Representative
4LlKI
Source
UniProt (cluster: phalp2_27411)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MTNKAQETWINAAVGRAIDPDRAYGLQCVDVVDDYAQACFPGVPWQKSVGGVAGARDLRRVNNAYFKWVPNIVGNNASIPARGDVMVYDGSSINPYGHTAVVLSATPTTVTVIQQDGFMQVRAHIATLGYDGPGTGPCLGWLRPLVKADPVPPKAVRVTRTVGPYGANERSAASHTSALKRKFKKGDVLTFKGYRLGTDPYKDGNNVWFVGAFSGTFFHSSGFVGGKSVAGLPKI
Physico‐chemical
properties
protein length:235 AA
molecular weight:25104,2 Da
isoelectric point:9,62
hydropathy:-0,16
Representative Protein Details
Accession
4LlKI
Protein name
4LlKI
Sequence length
690 AA
Molecular weight
73136,01860 Da
Isoelectric point
4,50201
Sequence
LSTNQYQEAWIASAPGRKVDRDNDASFDCVDVPKDYAINIWANTTWKDAWPGAGNACDMINTYNPEYFDRIDNDPNNPAQIPERGDVIVYGGAPINPAGHIAVVLDADQNGVDVVQEDSFMQCPMYVGRLGYTNAGTGECTGWLRPKFDATEQPVVTTAGNITFSQRVVGQYGVTERDAPSAHGNALRTFDPGTPLDFKGYVHGDAANGTDIWFVGAYAGNYFSASAFDDSSVAGLSDITPAPTPAPALQPYQRVVGVDSAIYRDASNTSGNVLATFKKGDTLNFKGYVHGQNVNGTDIWFVGSYSNGYISASNFDDSSTNGLSDLTPPAPAPVPAPAPAPAASATRTVGSQLNVRDAPYLNGNLVTTEPAGTVVTVKGYVPNGDSVNGNAVWFNIDKGWIWSGGVDSQSTAGLILLPTQARPSAPQYSGLNGIDISGAQKGIDLTKISLDFVIVKATEGVGWSDPEFQNNLGTARKTGKPVGFYHFARPLAQAGNTAQAEADSFVSVVKPILQPGDFVALDWEAENTSNVAWAKEWLDRVSAALGVKPLFYSYLNVLSANDFSSISSDYGLWYAQYPTAATQQGYGPVAAHAAVPGNWKIVVWQYSSAGILPGWTEKLDLDILFGNEADLAAIGYKAPAPSPQPAPAPTTTTDPAPAPSGTGTGPDKATIVSVLSSFFKWLTDLFVASR
Other Proteins in cluster: phalp2_27411
Total (incl. this protein): 22 Avg length: 546,0 Avg pI: 4,85
Protein ID Length (AA) pI
4LlKI 690 4,50201
4CKZ9 618 4,68429
A0A286N2U4 551 4,57232
A0A0U4JD12 551 4,64167
A0A0A7HER1 550 4,60068
A0A386K8H2 551 4,51139
A0A5J6TVJ8 551 4,59182
A0A6B9J793 551 4,60068
A0A1B1SFX7 551 4,64167
A0A1I9SCK7 551 4,64167
A0A1I9SCW9 551 4,64167
A0A1J0GRD2 551 4,64167
A0A1J0GRQ8 551 4,64167
A0A249XND5 551 4,64167
A0A286N359 551 4,64167
A0A286N3H0 551 4,64167
A0A286N3T2 551 4,64167
A0A286N444 551 4,64167
A0A482JFX9 551 4,64167
A0A5J6D8H3 551 4,64167
A0A5J6D9M7 551 4,64167
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_30739
7uirA
 8 24,1% 655 7.163E-102
2 phalp2_39460
4YhxB
 8 37,1% 468 6.684E-88

Domains

Domains [InterPro]
Unannotated
Unannotated
Unannotated
Unannotated
GH25
Disordered region
Representative sequence (used for alignment): 4LlKI (690 AA)
Member sequence: A0AA49E4U9 (235 AA)
1 690 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01183

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Bolt007
[NCBI] 		3017297 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP985600 [NCBI]
CDS location
range 21798 -> 22505
strand +
CDS
ATGACCAACAAGGCACAAGAGACTTGGATCAACGCCGCCGTCGGCCGGGCGATCGACCCCGACCGGGCCTACGGCCTACAGTGCGTCGACGTCGTCGACGACTACGCCCAAGCCTGTTTCCCGGGCGTACCGTGGCAGAAGTCCGTCGGAGGAGTCGCCGGGGCCCGCGACCTCCGCCGCGTCAACAACGCCTATTTCAAGTGGGTCCCGAACATCGTCGGCAACAACGCCTCGATCCCGGCCCGCGGCGACGTCATGGTCTACGACGGGTCCTCGATCAACCCCTACGGCCACACCGCCGTCGTCCTGTCCGCGACCCCGACGACCGTGACCGTGATCCAGCAGGACGGGTTCATGCAGGTCCGGGCGCATATCGCGACTCTCGGATACGACGGCCCCGGGACGGGCCCTTGCCTCGGCTGGCTCCGGCCCCTCGTCAAGGCCGACCCGGTCCCGCCCAAGGCTGTCCGCGTCACCCGGACCGTCGGACCCTACGGCGCCAACGAGCGCTCCGCCGCGTCCCACACCTCCGCCCTCAAGCGGAAGTTCAAGAAGGGCGACGTCCTGACCTTCAAGGGCTACCGCCTCGGGACGGACCCCTACAAGGACGGCAATAACGTCTGGTTTGTCGGGGCCTTCTCCGGGACGTTCTTCCACTCGTCCGGGTTCGTCGGCGGCAAGTCCGTCGCCGGGCTCCCCAAGATATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4LlKI) rather than this protein.
PDB ID
4LlKI
Method AlphaFoldv2
Resolution 80.05
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50