Protein

Protein accession
A0AA48XAC4 [UniProt]
Representative
8MohX
Source
UniProt (cluster: phalp2_36985)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKTQKQVVDYIKSLEGKGWDWDNAYGWQCFDTANYHANFAMGMSLAGEGAKDIPYKNDFTGKADLYNNTPEFLAQPGDIVVWTSPTFGGGYGHVASVISATLNTITVIEQNWLGGGRYMTEVATKRSHSYDPSMVFIRPKYAKSSTVTESKPTTVKPVTKPKAPATVNSSSGTKAIVKGKVPPKTLANSKDAYFRAKADKYGVNICKLQNGKYYPTGEVYQAGYDQFYIFEVKNGWARVYSNGNNGWVWFERLRVVEIFKNKTVAKAKATVAKAKKKVTPKKKSPAPKLKLAIGKKVPKGTIKVQKKPILQAKADSAGVTITTRNGTLKNEKYKPGQIFYVYEVTKDGYCRVYSPDNNGYVWHERLIITKVY
Physico‐chemical
properties
protein length:372 AA
molecular weight:41437,0 Da
isoelectric point:9,78
hydropathy:-0,54
Representative Protein Details
Accession
8MohX
Protein name
8MohX
Sequence length
372 AA
Molecular weight
41422,99270 Da
Isoelectric point
9,80269
Sequence
MKTQKQVVDYIKSLEGKGWDWDNYAGWQCFDTANYHAYFAMGMSLAGEGAKDIPYKNDFTGKADIYNNTPEFLAQPGDIVVWTSPTFGGGYGHVASVISATLNTITVIEQNWLGGGISKTEVATRRSHSYDPSMVFIRPKYAKSSTVTESKPTTVKPVTKPKAPATSNSSSGAKAIVKGKVPPKTLSNSKGAYFRAKADKYGVNICKLQNGKYYPTNEVYQAGYDQFYIFEIKNGWARVYSNSNNGWVWFERLRVVEIFKNKTVAKAKATVAKAKKKVTPKKKTPAPKLKLAIGKKVPKGTIKVQKKPILQAKADSAGVTITTRNGTLKNEKYKPGQIFYVYEVTKDGYCRVYSPDNNGYVWHERLIITKVY
Other Proteins in cluster: phalp2_36985
Total (incl. this protein): 8 Avg length: 374,8 Avg pI: 9,72
Protein ID Length (AA) pI
8MohX 372 9,80269
7e7qE 384 9,60735
7e7sK 384 9,45991
A0A1X9I9I9 372 9,80269
A0A7U0G8N1 372 9,77806
A0AAU8GRY9 370 9,75312
A0AB39C825 372 9,76233
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23551
7qsYO
 131 37,5% 378 2.471E-140
2 phalp2_30752
7BwRD
 72 44,4% 277 4.372E-51
3 phalp2_5797
4VENb
 15 24,6% 333 1.651E-11

Domains

Domains [InterPro]
CHAP
Unannotated
Unannotated
Representative sequence (used for alignment): 8MohX (372 AA)
Member sequence: A0AA48XAC4 (372 AA)
1 372 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Mammaliicoccus phage vB_MscM-PMS3
[NCBI] 		2861056 Herelleviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
MZ573780 [NCBI]
CDS location
range 32775 -> 33893
strand -
CDS
ATGAAAACACAAAAACAAGTTGTGGACTATATAAAATCCCTAGAAGGTAAAGGTTGGGATTGGGATAATGCATATGGTTGGCAATGCTTCGATACTGCTAACTATCACGCTAACTTTGCAATGGGAATGTCATTAGCCGGTGAGGGTGCTAAGGATATACCTTATAAAAATGACTTCACAGGTAAAGCAGACCTTTATAACAACACACCGGAATTTTTAGCACAACCAGGTGATATTGTAGTATGGACTAGTCCTACTTTTGGTGGTGGATATGGTCACGTTGCCTCTGTTATTAGTGCTACACTTAACACAATAACTGTAATCGAGCAGAATTGGTTAGGAGGGGGTAGATATATGACAGAAGTTGCTACTAAACGTTCTCACTCATACGACCCGTCAATGGTATTTATTAGACCTAAGTACGCTAAAAGTTCTACAGTTACGGAAAGTAAACCTACTACAGTTAAACCAGTTACTAAACCTAAAGCACCTGCAACAGTTAATAGTTCAAGTGGAACTAAAGCTATTGTCAAAGGAAAAGTACCACCTAAAACTTTAGCTAATTCTAAAGATGCTTACTTTAGAGCTAAGGCAGATAAATATGGTGTAAACATTTGTAAGTTACAAAATGGTAAGTACTACCCAACAGGAGAAGTTTACCAAGCAGGATATGACCAATTTTATATCTTTGAAGTTAAAAACGGTTGGGCTAGAGTATATTCAAACGGTAATAATGGTTGGGTATGGTTTGAACGATTAAGAGTTGTAGAAATCTTTAAAAACAAAACAGTTGCTAAAGCTAAAGCTACAGTAGCTAAAGCTAAGAAAAAAGTTACACCTAAGAAAAAATCACCGGCACCAAAACTTAAATTAGCAATCGGTAAAAAAGTTCCTAAAGGAACAATAAAGGTTCAAAAGAAACCTATACTACAAGCTAAAGCAGATAGTGCAGGGGTTACAATTACAACTAGAAATGGTACACTTAAGAATGAGAAATACAAACCGGGTCAAATATTCTATGTTTACGAAGTTACTAAAGACGGGTATTGTAGAGTATATTCACCGGATAATAACGGTTATGTATGGCACGAGAGATTAATCATTACTAAAGTATACTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8MohX) rather than this protein.
PDB ID
8MohX
Method AlphaFoldv2
Resolution 78.77
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50