Protein

Protein accession
A0A9X9P5J8 [UniProt]
Representative
59VXD
Source
UniProt (cluster: phalp2_107)
Protein name
Lysin A, protease M23 domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVTRYHPMKKGYIITSPFGWRDFDKAVHQGIDFGHPDGSGGMPVFAVQAGTVIMAGTAQGYGGPDPHGWLVIDSDDSQGSGVFEYGHITRLPSITVGTKVKAGQRIATINPNRSTNGGTAPHVHISYMPYEYNPNKKQNWSGKLAGAPYPDAPAPAPAPAPTPPKETPVAAADDVKLQLRGPKDNGWPQLAAQPDDNGVRFSPAQNGHRDALSLVDGLAVVVKEVTLRLPRATRGVRDYLSRKGDTVAGNAANAAAIAYENNVMLKALCRKEGIALESLTDLER
Physico‐chemical
properties
protein length:284 AA
molecular weight:30266,8 Da
isoelectric point:8,84
hydropathy:-0,43
Representative Protein Details
Accession
59VXD
Protein name
59VXD
Sequence length
439 AA
Molecular weight
46868,65040 Da
Isoelectric point
5,19704
Sequence
VTEKILPYNADLAAQETGYWCGPASAQMCLSDRGIHVEEHILAAKCQTHEGGTDHLGLIERVLNEYVHNADYITVSLPNDPPTQDEVETFWNNLRTSVDAGFGLVINFVAPQNNIPFPIKGSGPAPSFYNFGTTYHYVSAHGYSDEDNQQAVWITDSGGPSTPGKWGYWLTLAQTVLLAAGKGYIWARPHGSVHAPALPGPAPVATQGRFWPVTADRIVTSPFGPRWGTIHTGVDFGFNGGAGDRPVFAVQSGTVIFSGAAAGYGGPDPCGWLVIDSDDSQGGGVWEYGHIVREHALTVGAKVQAGQQIGIINPNEGTNGGVAAHLHLSYMPRGYDPGAKVDPLPVLDGSNEPGVHHEPPPPVHEPAPEPPPVHHEPPPTMMPTPLTGRPFHHSQADDLEGTLLSLRAEGLLTQALVFALAEKAGINARELYENVRGSF
Other Proteins in cluster: phalp2_107
Total (incl. this protein): 44 Avg length: 431,8 Avg pI: 5,80
Protein ID Length (AA) pI
59VXD 439 5,19704
132Bl 482 5,21125
18N10 410 5,31890
3blu2 434 4,71215
3bmMy 472 4,72630
4GC54 430 4,76160
4Oqcn 435 4,98793
4OtXN 472 5,40700
4lR1t 440 5,27906
4lS9B 435 5,33305
4mBiH 472 5,30498
4mYlV 435 5,27286
4nQB2 517 8,39425
4p7He 277 5,02078
4pQJP 440 5,25070
4qj7Q 435 5,33305
4qp26 472 5,24257
5AF6f 475 5,22608
5afk3 434 5,15276
5agx5 472 5,40950
5ec2j 472 5,41325
5eet3 436 5,40069
5ew3q 297 4,95070
5iJjF 473 5,23910
5oaYp 251 4,90347
5uSSU 477 5,35454
5v6yd 339 5,30310
5v9yM 472 5,30060
5vclu 435 5,14793
5w4Js 472 5,29355
5wIy5 479 5,28747
6RSGo 495 5,73565
7AJLH 516 6,89812
7Aslq 520 7,16964
7PTIi 520 6,42584
7PUlR 520 6,27380
7PYfi 516 6,50661
7aRMI 517 7,15105
8msWb 300 4,85038
aE0P 472 5,20591
A0A160DE94 284 8,52067
A0A160DGG1 287 8,52190
A0A5J6TC78 286 8,82264
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_9506
1175H
 95 28,4% 474 1.512E-96

Domains

Domains [InterPro]
PET_C39
PET_M23
Disordered region
Representative sequence (used for alignment): 59VXD (439 AA)
Member sequence: A0A9X9P5J8 (284 AA)
1 439 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Hollow
[NCBI] 		2985315 Demosthenesvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP434448 [NCBI]
CDS location
range 40911 -> 41765
strand +
CDS
ATGGTTACTCGATACCACCCCATGAAGAAGGGGTACATCATCACCAGCCCTTTCGGGTGGCGCGACTTCGACAAGGCCGTACATCAGGGCATCGACTTCGGTCACCCCGACGGCTCGGGTGGCATGCCAGTGTTCGCCGTCCAGGCGGGTACGGTCATCATGGCAGGTACCGCTCAGGGCTACGGTGGGCCTGATCCGCACGGCTGGCTCGTCATCGACTCGGACGACAGTCAAGGTTCGGGCGTGTTCGAGTACGGACACATCACTCGACTGCCCTCGATTACGGTCGGCACAAAGGTCAAGGCTGGTCAGCGTATCGCTACGATCAACCCGAACCGCTCGACCAACGGCGGCACTGCACCTCACGTGCATATCAGCTACATGCCTTACGAGTACAACCCGAACAAGAAACAGAACTGGTCCGGCAAGCTTGCCGGTGCGCCGTACCCGGATGCTCCGGCACCCGCGCCAGCACCGGCACCAACCCCACCGAAGGAGACTCCAGTGGCAGCAGCAGACGACGTGAAGCTCCAGCTTCGCGGACCCAAGGACAACGGCTGGCCTCAGCTCGCAGCGCAGCCCGACGACAACGGGGTGCGCTTCTCGCCAGCCCAGAACGGACACCGCGATGCGCTATCGCTCGTCGATGGTCTCGCGGTCGTGGTCAAGGAAGTCACCCTTCGACTGCCGCGCGCAACGCGGGGCGTCCGTGACTACCTCTCCCGCAAGGGTGACACGGTCGCTGGCAACGCGGCCAACGCAGCAGCCATCGCGTACGAGAACAACGTGATGCTCAAGGCCTTGTGCCGCAAGGAGGGCATCGCGCTCGAGAGCTTGACCGACCTGGAGCGATAG

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (59VXD) rather than this protein.
PDB ID
59VXD
Method AlphaFoldv2
Resolution 79.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50