Protein

Protein accession
A0A9X9HS91 [UniProt]
Representative
8qYns
Source
UniProt (cluster: phalp2_9794)
Protein name
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MYPKRITVHCSANRKGRYLTATELRKFHTDPEPVGKGWSDIGYHFVIRTDGAVDKGRPITRQGAGVGGQNKDNVHICLVGGLDAKGKPAFTYTDVQMNALYGLISDLTDKYQIPLDKVCGHRDYSPDLNGDGNITEDEWIKVCPCFDVRSWFKALCENNEVAYG
Physico‐chemical
properties
protein length:164 AA
molecular weight:18284,5 Da
isoelectric point:6,94
hydropathy:-0,52
Representative Protein Details
Accession
8qYns
Protein name
8qYns
Sequence length
241 AA
Molecular weight
26578,00370 Da
Isoelectric point
9,87445
Sequence
MGFRPTQIIVHCAATPEGKDFTVADIARWHKKRGFSGRGGTHCGYHFVIYRDGSIHAGKPEGVRGTHTRGHNWNSLGVCYIGGVDRKGKAKDTRTAAQKRALKKLIQELCDRHNIKKIRGHRDYAAKACPSFDARTEYSAIRPGRKFVNKPITKSRIAFRASAAGGGGAVLTTDSALGLMHTARDAQSHIEVGDVLGLVIGVATFLFAVGAVYARWDDAGRPSMRTMWREFWDEDPNEMEV
Other Proteins in cluster: phalp2_9794
Total (incl. this protein): 5 Avg length: 187,8 Avg pI: 7,88
Protein ID Length (AA) pI
8qYns 241 9,87445
44YhE 206 9,03004
A0A7G5B058 164 6,64211
A0A9X9N085 164 6,93910
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28171
8yYQh
 287 33,8% 204 1.207E-38
2 phalp2_7758
71AR5
 15 36,3% 168 1.787E-31
3 phalp2_14613
5sQyS
 2 33,5% 161 3.187E-26
4 phalp2_25618
48uUY
 31 36,8% 163 9.531E-25
5 phalp2_18379
5Eq5Q
 10 31,7% 164 4.457E-24
6 phalp2_28594
878Gz
 18 36,4% 151 6.066E-24
7 phalp2_30941
13o5z
 7 31,1% 228 4.516E-22
8 phalp2_5227
85bE8
 16 35,5% 166 1.534E-19
9 phalp2_18287
4ZlaN
 11 31,7% 205 5.361E-14

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 8qYns (241 AA)
Member sequence: A0A9X9HS91 (164 AA)
1 241 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage vB_VpaS_CHI
[NCBI] 		2950474 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
ON457559 [NCBI]
CDS location
range 52647 -> 53141
strand -
CDS
ATGTATCCTAAAAGAATTACTGTTCACTGTAGCGCGAACAGAAAGGGTCGTTATCTAACCGCCACGGAACTTCGCAAGTTCCATACTGATCCGGAACCAGTGGGAAAAGGTTGGAGCGACATCGGTTATCATTTTGTTATCCGTACCGACGGTGCAGTGGATAAAGGACGTCCAATTACCCGTCAGGGTGCAGGCGTCGGCGGCCAAAACAAAGACAATGTTCACATCTGTCTTGTTGGCGGTTTAGACGCGAAAGGTAAACCCGCTTTTACGTACACCGACGTTCAAATGAATGCGTTGTATGGTCTTATCTCAGACTTAACGGACAAGTACCAAATCCCGTTAGACAAAGTTTGTGGTCACCGTGACTATAGCCCGGATCTAAATGGGGATGGCAACATTACAGAAGACGAATGGATTAAAGTTTGTCCATGTTTTGACGTTCGTTCATGGTTTAAAGCTCTATGTGAAAACAACGAGGTTGCCTATGGATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8qYns) rather than this protein.
PDB ID
8qYns
Method AlphaFoldv2
Resolution 78.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50