Protein

Protein accession
A0A9N6WUH3 [UniProt]
Representative
1ditH
Source
UniProt (cluster: phalp2_2996)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MMINEAKKHLNANLEQKYRIIDYYNKHCLPLVKDSRKYRVQYNDNWCATFTSVIAHKCGLTKTDFPYECGVEEQVKLAKLRGKFYTDTDLVQPNDLIIYDWDVNNWADHVGIVIEKSDGTIKVIEGNIRNTVGYRTVPITSKSIRGFIRVGVDRKMLDADAERERIGDLARDTVAGKYGNGLERQRALGADYKAVQQYINVYYK
Physico‐chemical
properties
protein length:204 AA
molecular weight:23551,6 Da
isoelectric point:8,88
hydropathy:-0,55
Representative Protein Details
Accession
1ditH
Protein name
1ditH
Sequence length
155 AA
Molecular weight
17594,03430 Da
Isoelectric point
8,61344
Sequence
MNDKTALKYIALFLTGLKCDKRKFIIDYYNHYCIQKVKPTNRYYLQPNDNWCGAFVSVCAHMSRFEASNFPYGVSVHSQMIMAKNLLELTTNSEKVTSGDLVLFDWEGDGLPNHIGIVESVINGVIVSVEGNYSNDIKTRTINKSNNKIKGYIII
Other Proteins in cluster: phalp2_2996
Total (incl. this protein): 38 Avg length: 178,5 Avg pI: 8,36
Protein ID Length (AA) pI
1ditH 155 8,61344
1a7ho 133 6,82229
1dJqn 202 8,91077
30Or 203 7,68511
39P0R 128 6,10857
39Rp9 152 7,68693
3O6Iw 201 8,38387
3aF2c 202 8,84721
3aK8W 202 8,39225
3bvih 202 8,69209
3dRy1 209 7,63128
3etqQ 207 9,09554
3gy3L 155 8,22857
4VkXB 202 8,38207
4b6W 203 8,91077
66vCy 202 9,25419
67uvf 151 8,48747
6qGjM 162 9,57841
7Xhov 151 7,74928
7Y9Uo 202 9,39345
7Y9pF 152 9,09715
7Z732 195 9,35083
7Z7mK 148 8,63220
7Z81w 193 9,17864
7Z8bh 208 8,76552
7zP8K 151 8,48741
8aU96 151 7,74928
8briH 195 6,32836
8n3kS 151 6,05178
8nFaU 196 9,33962
8nYNW 168 9,00741
8oo5K 203 8,99336
ugVH 199 5,86905
x3sc 193 9,62360
A0A3G8F2N9 151 8,48741
A0A2D2W5Y0 149 9,20578
A0A6G8RBC1 151 7,70068
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17177
39QAi
 1 39,3% 99 6.377E-41
2 phalp2_10363
1FVFV
 9 32,5% 129 1.731E-34
3 phalp2_19272
7YZUV
 4 23,8% 155 3.058E-18
4 phalp2_15417
23J6d
 5 26,9% 115 6.245E-16
5 phalp2_7376
4z8rc
 8 26,1% 111 1.167E-15
6 phalp2_19200
23OeP
 1 28,6% 122 2.348E-13
7 phalp2_39189
3e3Uk
 1 20,7% 111 4.378E-13
8 phalp2_12692
24HVL
 5 24,5% 110 7.200E-12
9 phalp2_39649
6OclU
 48 26,5% 113 3.543E-09
10 phalp2_19771
7LzfF
 669 24,0% 104 8.947E-09

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 1ditH (155 AA)
Member sequence: A0A9N6WUH3 (204 AA)
1 155 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Acinetobacter phage Phanie
[NCBI] 		3029265 Astrithrvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OX458330 [NCBI]
CDS location
range 10350 -> 10964
strand +
CDS
ATGATGATTAACGAAGCTAAGAAGCACTTAAATGCTAACCTTGAACAAAAGTATCGCATTATTGACTATTACAACAAGCATTGCTTGCCATTGGTTAAAGATTCTCGTAAATATCGAGTTCAGTATAATGACAACTGGTGTGCAACGTTTACGTCTGTGATAGCTCATAAATGTGGACTTACTAAAACCGATTTCCCTTATGAATGTGGAGTTGAGGAGCAAGTAAAGTTAGCAAAATTACGTGGTAAGTTCTACACTGACACAGATTTAGTTCAACCTAATGACCTCATTATCTACGATTGGGATGTTAACAATTGGGCAGATCATGTGGGGATTGTAATTGAAAAGTCAGACGGGACTATCAAAGTCATTGAGGGCAACATCCGTAATACTGTGGGTTATCGCACTGTTCCTATTACTTCAAAATCTATACGTGGGTTTATCCGTGTGGGTGTTGATCGTAAAATGCTTGATGCTGATGCAGAACGTGAACGCATTGGTGACCTTGCTAGAGACACTGTAGCAGGTAAATATGGTAACGGATTAGAGCGCCAGAGAGCGCTAGGAGCAGATTATAAGGCAGTGCAGCAGTATATTAACGTATACTACAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0016787 hydrolase activity molecular function None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1ditH) rather than this protein.
PDB ID
1ditH
Method AlphaFoldv2
Resolution 96.70
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50