Protein

Protein accession
A0A9E8MB40 [UniProt]
Representative
7uLD9
Source
UniProt (cluster: phalp2_29168)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MNKLWGIDMGHTLSGADTGASGIVTEQIEDRKIGKALISDLESVGDRVVNCTTDSASSLDASLAHRYNTANNAGVDGFVSLHLNSSKDPSAHGVEVLIHARGGEAEQMAKRVLVELAKLGYYNRGIRVAREYLGYDLAVLKYTNAPAILVECGFVSSQKDCNLLNPSAIAAAICKGLTGQEGSGSGDYDNTPSLPEAPKGFYESSETRTNATLVGEGSIEVLDEDCKPIPGRYIDSLDNLFVLGIYPSRKYIEVIYPGKNSNYHAYIDIKHYSRLSFDYHMKYQNDNGVTYVWWDPKNVNVTDCDETLQPGQKASPMYRTNGWLRITFYRKDGTPSDGYVRYEGEQSQKFYEDVKQGIVRVNTSLNVRDDVNGNIIGSVFNNERVTILGSKNGWYHIEYNTSHGKKQGYVSSKYVEII
Physico‐chemical
properties
protein length:418 AA
molecular weight:46246,0 Da
isoelectric point:5,64
hydropathy:-0,46
Representative Protein Details
Accession
7uLD9
Protein name
7uLD9
Sequence length
377 AA
Molecular weight
43489,81990 Da
Isoelectric point
6,60966
Sequence
MYINQSNIKFNGLNYGNNPNKIIIHNADHPNCSVYDVDRWHKGNGWSGIGYHYFIRKDGSVWTGRPENAKGAHTIGQNSSSIGICLEGALMREKPTRAQLNSLYYLISDIRARRGNLPVYGHKDFNNTDCPGINFPLEQFKNNSYRPTGGTEISDNGFYRSDEERTNATIVGEGNIEVLDKNCKVIENRYISSLDRVFVLGIYPASKHIEIIYPAGNEKYHAYISIENYSRISFDYHMQYKNDNGITYVWWDSEDVNVKEHNEELQPNQKASPMYRVGKWLRVTFYRTDGTPSDGFVRYEGEQSVKFYEDEKIKDGIVKVNTYLNVRDSINGNIIGKVFNGEEVSIIWTKDGWYYIEYNTNHGKKRGYVSSKYVEEV
Other Proteins in cluster: phalp2_29168
Total (incl. this protein): 35 Avg length: 349,0 Avg pI: 6,99
Protein ID Length (AA) pI
7uLD9 377 6,60966
5UKgu 391 7,96637
6An4R 394 5,28497
6bbXD 395 6,02194
7Bmys 389 7,14969
7Rs6O 392 5,84438
7Z7fb 395 6,47012
7Z8oY 395 8,69816
7hinP 379 8,15469
7nWm1 379 8,87087
8Isq5 388 6,89414
8Isq6 388 6,36366
8M5dW 377 5,97761
8oorC 429 5,53819
A0A343X847 226 8,73020
I3PV70 226 8,98059
I3PV40 227 7,69290
A0A1L6BY22 388 6,89414
A0A249XXD2 388 6,36366
M9Q1I7 377 5,97761
A0A5H2TM76 416 6,27135
A0A6M3A3C9 412 6,18183
A0A9E7CBT9 227 8,22689
A0A9Q7BCC9 227 8,22689
A0A9Q7BLM7 227 8,22689
A0A9Q7BLN4 227 8,22689
A0A9Q7FDM2 227 7,67999
A0AA45K217 227 8,22689
A0AAE9GAZ6 224 8,93501
A0A9E8MA73 418 5,63811
A0A9E8S3N3 418 5,63811
A0A9E8S405 418 5,63811
A0A9E8S429 418 5,63811
A0A9X9JSB4 412 5,86672
Similar Clusters

No similar clusters were found for representative 7uLD9.

Domains

Domains [InterPro]
Ami2
Unannotated
SH3_3
Representative sequence (used for alignment): 7uLD9 (377 AA)
Member sequence: A0A9E8MB40 (418 AA)
1 377 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510, PF08239

Taxonomy

  Name Taxonomy ID Lineage
Phage Clostridium phage E1
[NCBI] 		2999105 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP753453 [NCBI]
CDS location
range 20626 -> 21882
strand -
CDS
ATGAATAAATTATGGGGAATTGATATGGGACACACATTATCCGGAGCAGATACTGGGGCTTCAGGTATAGTAACTGAGCAAATTGAGGATAGAAAAATAGGTAAAGCCCTAATCAGCGATTTAGAGTCTGTTGGTGATAGGGTGGTTAATTGTACTACTGATTCTGCCTCTTCTCTAGATGCTAGTTTAGCACATAGATATAATACTGCTAATAATGCTGGAGTGGATGGTTTTGTATCATTACATTTAAATTCTAGTAAGGATCCATCAGCTCATGGTGTTGAGGTACTAATTCATGCTAGAGGTGGAGAAGCTGAACAAATGGCTAAGAGAGTATTAGTTGAACTTGCTAAGCTTGGGTATTATAACAGAGGTATAAGAGTTGCTAGAGAATATTTAGGTTATGACCTAGCGGTACTTAAATATACTAATGCACCGGCTATATTAGTTGAATGTGGCTTTGTATCAAGTCAGAAGGATTGTAATTTATTAAATCCTAGTGCTATAGCTGCTGCTATATGTAAAGGACTAACTGGTCAAGAAGGATCTGGCTCAGGGGATTATGATAATACCCCAAGCTTACCTGAGGCCCCTAAGGGATTTTATGAAAGTTCCGAAACAAGAACTAATGCCACTTTGGTAGGGGAAGGTTCAATAGAAGTCCTAGATGAGGATTGCAAACCTATTCCAGGTAGATATATTGATAGTCTAGATAATTTGTTTGTCCTTGGGATATACCCTTCTAGAAAATATATTGAAGTTATATATCCTGGAAAGAACAGCAATTATCATGCTTACATTGATATAAAGCATTACAGTAGATTAAGTTTTGACTACCACATGAAATATCAAAATGATAATGGGGTTACTTACGTATGGTGGGACCCAAAGAATGTGAATGTAACTGACTGTGATGAGACTTTACAACCAGGTCAAAAGGCTAGTCCAATGTATAGAACTAATGGCTGGTTAAGAATAACATTTTATAGAAAGGATGGTACTCCATCTGATGGATACGTTCGTTACGAGGGTGAGCAAAGCCAGAAATTCTATGAGGATGTTAAACAAGGAATAGTTAGGGTTAACACTTCTCTTAATGTAAGAGATGATGTGAATGGTAATATAATAGGCTCAGTATTTAATAATGAGAGAGTTACTATATTAGGAAGTAAGAATGGTTGGTATCATATAGAATATAATACTAGCCATGGTAAGAAGCAAGGTTATGTAAGTTCAAAATATGTAGAGATAATTTAG

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

EC Number Entry Name Reaction Catalyzed Classification Evidence Source
3.5.1.28 None Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides. N/A UniProt

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7uLD9) rather than this protein.
PDB ID
7uLD9
Method AlphaFoldv2
Resolution 90.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50