Protein

Protein accession
A0A9E8M2V6 [UniProt]
Representative
42vZA
Source
UniProt (cluster: phalp2_3109)
Protein name
Lysin A, protease C39 domain
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKMAAGDVVLKFDHVIIPQETYYWCGPATMQVLLSIRGIKVTEKYMADQLGTTENGTDTILYLTRELNERLGDIYRTVQVPGAGNLDQFREHVFHSIDAGYGVGGNIMVPPANYPRPQRGERAQYSGGWIYHYWSIVGKNERLDQMAIADSGFPDFYYWVTSEQALSMISGKGYTWAANAKVADDFLGSLSDADQRRVLAAAIQVSEPHRGA
Physico‐chemical
properties
protein length:212 AA
molecular weight:23648,4 Da
isoelectric point:5,51
hydropathy:-0,29
Representative Protein Details
Accession
42vZA
Protein name
42vZA
Sequence length
549 AA
Molecular weight
60894,25120 Da
Isoelectric point
4,38703
Sequence
MTDPVSVLADAMQWSVTYERYAELYPALSQSLRESECTTYDRIAMYCAQTGHESAGLYYMEEQDWNGDNYAYLEGRCDDLGNCSPGDGAKYHGRGPIQVTGKYNYTECSQWAFDEGLAPSPTFFVDIPEELAQDDNGFHGVTWYWTTQRPMNDAADAHDIYLATYYINGGYNGIEDREQRYNHCMSMGDLLLVLLQPKDERPLVGERVLSYNPDIIPQETGYWCGPASAQMCLDMRGIYESEQTLANEMGTDDGGTDYVALIEQSLDPRLPEANYSSHDAPHDPPSAPEKEALWDALKRSIDNGYGVVMNWVAPPANYPIGIKGSPNPSYGGGTVFHYVSAAGYDDNPSQRAVWIVDSGFQPWHYWISFDQCCTLIPPKAFCYANLPHTGGGEPMSDETVWVYEQLCGPINPATGYGSGWPQLGQNEHGQNLYYVDALGRTLAMLEGEPFTDIQAQPTAAPRNPLDYSALSLDQLAGPVTADGERHGWPQLGNRSVTDTQAHINSLLSEDSGEPPLQKAHQEQSSLVGNRLSSRLRERGQRQEPDSPAT
Other Proteins in cluster: phalp2_3109
Total (incl. this protein): 6 Avg length: 307,5 Avg pI: 5,09
Protein ID Length (AA) pI
42vZA 549 4,38703
6IggY 454 4,34332
A0A386KFM4 210 5,51591
A0A2D1GCZ8 210 5,49988
A0A0K0N611 210 5,30805
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28047
725I0
 68 47,1% 443 5.708E-126

Domains

Domains [InterPro]
GH19
PET_C39
Unannotated
Disordered region
Representative sequence (used for alignment): 42vZA (549 AA)
Member sequence: A0A9E8M2V6 (212 AA)
1 549 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00182, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Gordonia phage Dalilpop
[NCBI] 		2998886 Zierdtviridae > Gruunavirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP867020 [NCBI]
CDS location
range 38988 -> 39626
strand +
CDS
GTGAAGATGGCCGCTGGCGACGTCGTACTGAAGTTCGACCACGTGATCATTCCGCAGGAGACGTACTACTGGTGCGGGCCTGCGACGATGCAGGTGTTGCTGTCGATCCGCGGCATCAAGGTCACCGAGAAGTACATGGCCGACCAGCTCGGGACCACCGAGAACGGCACCGATACCATCCTCTACCTCACCCGCGAGCTGAACGAGCGCCTCGGAGACATCTACCGGACCGTGCAGGTCCCGGGAGCCGGGAACCTCGACCAGTTCCGCGAGCACGTCTTCCATTCGATTGACGCGGGGTACGGCGTCGGCGGCAACATCATGGTGCCCCCGGCCAACTACCCGCGGCCACAGCGCGGAGAGCGCGCGCAGTACAGCGGCGGGTGGATCTACCACTACTGGTCGATCGTCGGGAAGAACGAACGCCTCGACCAGATGGCCATCGCCGACAGCGGGTTCCCCGACTTCTACTACTGGGTCACCAGCGAACAGGCGCTCTCGATGATCTCCGGTAAGGGGTACACCTGGGCCGCAAACGCCAAGGTCGCCGACGACTTCCTCGGGTCCCTGTCCGACGCCGACCAGCGTCGCGTGCTCGCCGCCGCGATCCAGGTCTCCGAGCCCCACCGAGGAGCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0006508 proteolysis biological process None (UniProt)
GO:0008233 peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (42vZA) rather than this protein.
PDB ID
42vZA
Method AlphaFoldv2
Resolution 86.78
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50