Protein

Protein accession
A0A9E8K5E9 [UniProt]
Representative
4M8WF
Source
UniProt (cluster: phalp2_33123)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
VAL
Probability: 73% (predicted by ML model)
Protein sequence
MTLIRKGSRGYDVKIIQEYLTKCGYDTNGVDGIFGGGSDKATRDFQKDFGLGVDGIVGNGTASKLLDIYWTDISDKAEDLPWMQEAFKDYFVSEIKGEKHEPKVLAFWKDAKLGGIKDDETPYCSGAVSAWLERAGIRSQRTAWARNYLNQGVKVEEPRFGAIVVVSRGKGGHVGFVTGVTKDGSQIRVLGANQSDSVNERMFDVNRVLGYRNPHQDFTLPDAPIIDSDVTSKNEA
Physico‐chemical
properties
protein length:236 AA
molecular weight:26021,9 Da
isoelectric point:5,71
hydropathy:-0,47
Representative Protein Details
Accession
4M8WF
Protein name
4M8WF
Sequence length
264 AA
Molecular weight
28611,07340 Da
Isoelectric point
9,60832
Sequence
MVKVLKTDPPWLRRAFADLGLKEVPGKGSNPRIVEMYALAKNSGVKEDSVPWCSAAVNAWMAESGIEGTRSLLARSWLAWGTKPALKPLPRGAVLIFKRGNSSWQGHVCLLLEDNGSVLTVIGGNQSDAVTIARYRRTSLIGARWPVTPIKPATKPIPEPAPEMEALPAPDVEEVPPEGVPPHMPPDVEPLEAPVEHGAWGWMKRRWRGASGVGGFSIFAFLTDPWVWAVLIGGAIVVALIALVIALFLFGRQRVASWVRGKIG
Other Proteins in cluster: phalp2_33123
Total (incl. this protein): 3 Avg length: 312,3 Avg pI: 7,92
Protein ID Length (AA) pI
4M8WF 264 9,60832
A0AAX4QJ16 437 8,44699
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17303
4eTLb
 16 42,7% 187 8.470E-45
2 phalp2_32166
6PqA1
 486 41,9% 174 2.325E-42
3 phalp2_21029
9AcO
 22 39,4% 170 2.168E-34
4 phalp2_37558
3GCv7
 1 31,9% 266 4.514E-26
5 phalp2_27942
Cm1J
 135 27,8% 176 3.593E-19
6 phalp2_2345
4T4j2
 3 29,7% 235 1.683E-15

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 4M8WF (264 AA)
Member sequence: A0A9E8K5E9 (236 AA)
1 264 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage vB_VpaM_R16F
[NCBI] 		2996088 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP793884 [NCBI]
CDS location
range 125643 -> 126353
strand +
CDS
ATGACTTTAATTCGTAAAGGTAGTCGTGGTTATGATGTAAAAATTATCCAAGAATACCTAACAAAATGTGGTTATGATACTAACGGAGTAGATGGTATTTTTGGTGGTGGTTCTGATAAAGCAACTCGTGACTTTCAGAAAGATTTTGGACTGGGGGTAGATGGAATAGTCGGTAATGGGACCGCATCCAAACTACTAGATATTTATTGGACAGATATTTCCGATAAAGCTGAAGATTTGCCTTGGATGCAGGAAGCTTTTAAAGATTACTTTGTTTCCGAAATTAAGGGTGAAAAGCACGAACCAAAAGTGTTAGCTTTCTGGAAAGATGCTAAACTTGGTGGTATAAAAGATGATGAGACACCATATTGTTCCGGTGCAGTAAGTGCTTGGTTGGAACGTGCAGGTATTCGTTCACAAAGAACTGCTTGGGCACGTAATTATCTTAACCAAGGAGTTAAGGTAGAAGAACCTAGGTTCGGTGCTATTGTGGTGGTTTCACGAGGGAAAGGAGGGCATGTTGGTTTTGTTACTGGAGTCACTAAAGATGGTTCACAGATCCGTGTTTTAGGTGCAAATCAATCGGATTCCGTAAATGAACGTATGTTTGATGTTAATAGAGTATTAGGTTATCGAAACCCACATCAAGATTTCACACTCCCTGATGCCCCTATAATTGATTCAGATGTAACTAGTAAGAATGAAGCTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4M8WF) rather than this protein.
PDB ID
4M8WF
Method AlphaFoldv2
Resolution 80.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50