Protein

Protein accession
A0A9E8G463 [UniProt]
Representative
3TI73
Source
UniProt (cluster: phalp2_25586)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKPQFITVHCSASKTGRYLTASEIRTMHTRPKSQGGNGWSDIGYHAVIRTDGAVEMGRPLTRMGAGVGGHNQNNLHVCLVGGVDSRGRSVDNYTAAQKNALFGLILDWQEQFNIPNEGVKGHRDWFGDTNGDGVIDSRDWYKDCPCFDVVIWFESQLRELGRL
Physico‐chemical
properties
protein length:163 AA
molecular weight:18140,1 Da
isoelectric point:7,00
hydropathy:-0,50
Representative Protein Details
Accession
3TI73
Protein name
3TI73
Sequence length
250 AA
Molecular weight
28120,65340 Da
Isoelectric point
8,75959
Sequence
MRPITKIILHCSANGPSCTFGAKEIRRFHTMPVSQGGRGWSDIGYHYVIKRDGTLEEGRPLEKAGAHTTGYNAESIGICLVGGVESDGRTPDDNFTTAQFETLARLIESLRSRWPKATIHGHSEFANKACPVFSVPKFLKSYGIEKDPSLVDWDSARWPHFKPGEFSALWGKGPMPLEWKKTLDALEDLRSMYGKPLYLERTSWQDNRLTCDIRVPSDKHAIFIRWAMDAGFTSARTVTANAVRVYGVWE
Other Proteins in cluster: phalp2_25586
Total (incl. this protein): 8 Avg length: 191,5 Avg pI: 7,69
Protein ID Length (AA) pI
3TI73 250 8,75959
23Jfa 243 9,29971
40kpy 263 8,48741
A0A088F6M8 163 6,28829
A0A2H5BG42 146 9,17651
A0A2I7QYZ5 152 6,47904
A0A2I7RRS0 152 6,02433
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7609
5IQgF
 2 28,1% 167 6.187E-17
2 phalp2_27876
8EUCV
 18 30,4% 161 1.535E-16
3 phalp2_7337
4jq41
 32 28,9% 183 2.813E-16
4 phalp2_36432
11r0n
 207 27,3% 179 6.550E-10

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 3TI73 (250 AA)
Member sequence: A0A9E8G463 (163 AA)
1 250 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Vibrio phage 033B
[NCBI] 		2966627 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP331229 [NCBI]
CDS location
range 40416 -> 40907
strand +
CDS
ATGAAGCCTCAATTCATCACTGTTCATTGCAGTGCGTCTAAAACAGGACGATATCTGACGGCTTCAGAAATCCGCACCATGCACACCAGACCGAAATCTCAGGGCGGCAACGGCTGGTCTGATATCGGGTACCATGCAGTGATCCGAACTGATGGTGCTGTAGAGATGGGAAGACCATTGACCAGAATGGGTGCCGGAGTGGGCGGCCATAATCAAAACAACCTTCACGTCTGCCTAGTAGGTGGAGTTGATAGCAGAGGCCGTTCTGTCGACAACTACACCGCAGCTCAGAAGAACGCGTTATTCGGACTCATCCTCGATTGGCAAGAACAATTCAATATCCCGAATGAAGGTGTCAAGGGGCACCGCGACTGGTTCGGGGATACCAACGGCGATGGCGTCATCGATAGTCGCGACTGGTACAAAGATTGCCCGTGCTTCGATGTGGTCATTTGGTTTGAGAGTCAACTGCGCGAGCTGGGGAGGCTATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3TI73) rather than this protein.
PDB ID
3TI73
Method AlphaFoldv2
Resolution 78.61
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50