Protein

Protein accession
A0A9E7TJI4 [UniProt]
Representative
2YkVl
Source
UniProt (cluster: phalp2_3311)
Protein name
M23 family metallopeptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MKVKLNGNDFFQVSSPFGSIDSVHKTPHSGIDLVMEEGTKLYSPVDGIVERVVDYGNQNIGKGVIIKTNTGETVIMGHMSDTSTAEVGEELSRGEFVGLSGNTGHSTGAHLHLGMKDANGNVINPEGLLNDNYKKLLNSRESLNPIEDKGMLEFLNDWRKEGFWKAVYGKDFFEVMKDTFIEFFRDLTQFIVDNADLFFLIPAIILMFGTFLIGRNKYSKFIVPLWFGYFVSSIVHNLYMK
Physico‐chemical
properties
protein length:241 AA
molecular weight:27081,6 Da
isoelectric point:5,50
hydropathy:-0,11
Representative Protein Details
Accession
2YkVl
Protein name
2YkVl
Sequence length
203 AA
Molecular weight
21561,04650 Da
Isoelectric point
5,47566
Sequence
VKVTFNGGEFYRVTTQFNSVDSLHKNGHTGIDLSMESGTKLLSPADGVVERIVDYGSQNIGKGVIVKIENGDRLIFGHMSDTSQVHVGDTLHAGDLVGLSGNSGRSTGAHLHFGVKDPQNNFTDPAPYLNGGSGKEIVQMPSPEGCGVFEKADAANIVSDSMSKFGDMLSDMTVNFIDIIHFTLLHAIPIMSRALGVILSSLS
Other Proteins in cluster: phalp2_3311
Total (incl. this protein): 25 Avg length: 225,5 Avg pI: 5,64
Protein ID Length (AA) pI
2YkVl 203 5,47566
34fgw 200 5,33669
7LVid 203 5,14816
7zVYw 202 5,28582
ifs 199 5,87206
U5JA48 240 5,98511
A0A516KMZ2 202 5,28582
A0A0A0RSR8 198 5,00021
A0A218KCF2 240 5,36653
A0A3G3BVF1 250 5,09962
A0A3T0IHR9 240 5,96732
A0A6C0RU44 199 5,21233
A0A6H0X6J4 240 5,98511
A0A7S6RB56 231 6,03706
A0A0A0RNJ7 199 5,87206
A0A9E7PI47 240 6,44693
A0A9E7PII7 240 5,37404
A0A9E7TDW6 240 5,37767
A0A9E7TF76 231 5,89838
A0AAE9CA80 240 5,89309
A0AAE9CC45 240 6,05849
A0AAE9CDU1 240 5,46140
A0AAE9CEA3 240 5,89309
A0AAE9CED9 240 6,05332
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_20625
4LnEC
 5 47,2% 129 2.156E-36
2 phalp2_14848
7w0BH
 74 32,3% 167 1.048E-15
3 phalp2_2494
5Ecd6
 8 32,9% 155 4.171E-14
4 phalp2_5933
67ENK
 29 36,2% 135 1.928E-13
5 phalp2_5799
4Wl1U
 14 33,0% 139 6.545E-13
6 phalp2_993
2vbyj
 4 30,6% 137 6.545E-13
7 phalp2_5764
7GfkS
 23 33,0% 127 3.880E-10
8 phalp2_27401
4JKVy
 8 28,4% 137 3.880E-10

Domains

Domains [InterPro]
PET_M23
Representative sequence (used for alignment): 2YkVl (203 AA)
Member sequence: A0A9E7TJI4 (241 AA)
1 203 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Bacillus phage vB_BanS-Thrax5
[NCBI] 		2951253 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
ON548421 [NCBI]
CDS location
range 8458 -> 9183
strand +
CDS
ATGAAGGTAAAATTAAATGGTAATGACTTCTTTCAAGTATCAAGTCCATTCGGCTCTATAGATTCAGTCCATAAGACACCACATTCTGGAATAGACTTGGTAATGGAAGAAGGTACAAAATTATACAGCCCTGTCGATGGTATTGTCGAAAGGGTTGTAGATTATGGAAATCAAAATATTGGTAAAGGTGTCATAATAAAAACCAATACAGGAGAAACTGTTATTATGGGTCATATGTCTGACACTTCAACAGCAGAAGTCGGAGAAGAGTTAAGTCGAGGTGAATTTGTGGGATTATCTGGAAATACAGGACATTCAACTGGCGCACATCTTCATTTAGGTATGAAAGATGCAAATGGAAATGTTATTAATCCAGAAGGACTATTGAATGATAACTATAAAAAACTTCTCAATAGTAGAGAATCACTTAATCCCATAGAAGACAAAGGAATGTTAGAATTTCTAAATGATTGGAGGAAAGAAGGATTCTGGAAAGCAGTATATGGAAAGGATTTCTTCGAAGTAATGAAAGATACATTTATAGAATTTTTTAGAGACTTGACACAATTTATAGTGGATAATGCAGATTTGTTTTTCTTGATACCTGCAATAATTTTAATGTTTGGAACATTTTTAATAGGGCGAAATAAATATTCAAAATTTATTGTCCCTTTATGGTTTGGGTACTTTGTTTCAAGTATTGTGCATAACTTATATATGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0016020 membrane cellular component None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (2YkVl) rather than this protein.
PDB ID
2YkVl
Method AlphaFoldv2
Resolution 77.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50