Protein

Protein accession
A0A9E7DTY0 [UniProt]
Representative
4N8u3
Source
UniProt (cluster: phalp2_31913)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAYLEDHPPTRSQFRRRYATPTGLIVVHTAESALDKIGADTGAEGVADFIRRRTDPGSYHRLVDSDSIVALVRFEMAAYGDGTGSNEFAIHLSFACRAADWPGMDPARREAFLVNGARAAREAAAWLREHHGITVPARRVTRTQSEQRAAGFISHGERDPGRRTDPGPAFPWDRFLTLYASEEDDMAQYDEQLDRIEKNTERTLRMADRHNAQRKAQAKRAMDRLNRLLALVTDGAAHTALADDLEALRVDVAALAEGDTADPAAEE
Physico‐chemical
properties
protein length:267 AA
molecular weight:29594,5 Da
isoelectric point:5,64
hydropathy:-0,59
Representative Protein Details
Accession
4N8u3
Protein name
4N8u3
Sequence length
302 AA
Molecular weight
33845,70570 Da
Isoelectric point
7,19891
Sequence
MAEESFYLLEHKNPHLDQYGEERRYDQTPSGTIVIHTAENVADQLGGDLGAENVAAYVVRRTNHGSYHRLVDADSIIKMAPFGYETWHCRNTNPWSIGISMAVMADDWDKYSDDYVMRVLRNAARAAAEAVRDLKKYWKVTVPLEHITGSQALAKRPGFTGHGETDPTRRHDPGSGFPWARFLNLVREELGDDPIEAEPVNNPITPAKPKPAPKPKGTEYRMNRLDLRTAHRTKIYNDDMKKWQGLLLAHGYGPRGLVETTGRPDGIGGAYTRRATLAFQKKAGIEEDAVVGPITWKKALEG
Other Proteins in cluster: phalp2_31913
Total (incl. this protein): 4 Avg length: 279,5 Avg pI: 7,15
Protein ID Length (AA) pI
4N8u3 302 7,19891
7zjfm 278 8,99735
aK7L 271 6,75403
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36881
7s6K6
 44 48,9% 186 3.221E-71
2 phalp2_6804
8e8u6
 16 38,2% 204 3.685E-43
3 phalp2_9231
6Te1j
 3 41,5% 195 2.075E-41
4 phalp2_27763
7dBL6
 2 33,5% 188 1.678E-35
5 phalp2_22201
6VaYI
 26 32,8% 283 1.446E-28
6 phalp2_29601
8d2YW
 52 28,3% 303 4.908E-28
7 phalp2_24092
8fabO
 1 33,1% 211 9.343E-23
8 phalp2_4929
6ytwW
 46 27,0% 299 6.370E-21
9 phalp2_31178
7Vvn5
 47 33,0% 206 2.863E-20
10 phalp2_18569
7cxQw
 45 30,7% 208 1.732E-19

Domains

Domains [InterPro]
Ami2
PG_1
Representative sequence (used for alignment): 4N8u3 (302 AA)
Member sequence: A0A9E7DTY0 (267 AA)
1 302 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Pseudanabaena phage Pam4
[NCBI] 		2936520 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
ON014756 [NCBI]
CDS location
range 46577 -> 47380
strand +
CDS
GTGGCCTACCTCGAAGACCACCCACCCACCCGCAGCCAGTTCCGCCGCCGGTACGCCACCCCGACCGGCCTTATCGTCGTCCACACCGCCGAGTCGGCACTCGACAAGATCGGCGCCGACACCGGAGCCGAAGGAGTCGCGGACTTCATCCGCCGCCGCACCGACCCCGGGTCCTACCACCGGCTCGTAGACTCCGACTCGATCGTGGCCCTGGTCCGGTTTGAGATGGCGGCCTACGGCGACGGCACCGGCTCCAACGAGTTCGCCATCCACCTCTCCTTCGCCTGCCGCGCCGCCGACTGGCCGGGCATGGACCCCGCCCGCCGCGAGGCCTTCCTCGTCAACGGCGCCCGGGCCGCACGCGAGGCCGCCGCATGGCTCCGCGAGCACCACGGCATCACCGTCCCGGCCCGCCGCGTCACCCGGACCCAGTCCGAGCAGCGCGCGGCGGGTTTCATCTCGCACGGCGAACGAGACCCCGGCCGCCGCACCGACCCCGGCCCCGCCTTCCCGTGGGACCGGTTCCTCACCCTCTACGCCTCTGAGGAGGACGACATGGCTCAGTACGACGAGCAACTCGACCGGATCGAGAAGAACACCGAGCGCACCCTGCGGATGGCTGACCGGCACAACGCCCAGCGCAAGGCTCAGGCTAAGCGCGCGATGGACCGCCTCAACCGGCTCCTTGCCCTCGTCACCGACGGCGCCGCCCACACCGCGCTGGCCGACGACCTGGAGGCCCTCCGCGTCGATGTCGCCGCCCTGGCCGAGGGCGACACCGCCGACCCCGCCGCCGAGGAGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4N8u3) rather than this protein.
PDB ID
4N8u3
Method AlphaFoldv2
Resolution 83.62
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50