Protein

Protein accession
A0A977KPR5 [UniProt]
Representative
8Lr6h
Source
UniProt (cluster: phalp2_509)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MILSNLAAKLRKHGLTVVETPGWANRGFLGRDLLEVRGVLWHHTATNRSRFASSPAPTLGMCIEGRPDVAGPLCNIVFGRDGAVYLAAAGLANHAGAGAAPNIPRDLGNYYLIGIEMESSGIAPWDWSPDQLRVAPYLGAALEREYLMHLPPELRLQIGHKEYSSTGKIDPAGWPGDMDGLRASINKVLAGGGTVKPASSGGSKPAPAPAPKPTTKGEQVPKHTRLYPPAVKRRLAPGAEWFLKDKTGKINLNLAGGTGGLGHYDVDLFVQGSGLAAGEVVEVQFYVVKPGKKPSGYFTQQVHGSASGEFKGRARFKMPLLESCRVEVGVKSSASCFLEVYGADVYNWQKEGK
Physico‐chemical
properties
protein length:353 AA
molecular weight:37662,7 Da
isoelectric point:9,35
hydropathy:-0,24
Representative Protein Details
Accession
8Lr6h
Protein name
8Lr6h
Sequence length
355 AA
Molecular weight
37690,22680 Da
Isoelectric point
6,98031
Sequence
MKLSNLAGKLRKHGLTVVETPGWAHRGFLGRDLLEVRGVLWHHTATNRVRFLGLNAPTLQMCIEGRPDVSGPLCHIVFGRDGTVYLTAAGLANHAGAGSAAGIPRDMGNHYLVGIEMESSGVAPWDWTEDQLRVAPHLGAALELELLQHLPAEERLQIGHLEYSSQGKIDPAGWPGGMDGLRSSINKVLAAGSGGGTINVASSGGSEAAPAPAPKPTKKGEEVPKHTIVASDHKPHRLPKSVDGSKVYRLSGKDDGTNQNFAVNGPGHYRVVTFLRGSGLPAGEKLTVTFELVKDGRISAYDKQDVLGSADGTFNHPVVLEYPIAGQLLNIAVESSVESAYVAGFRAHVVTWKEG
Other Proteins in cluster: phalp2_509
Total (incl. this protein): 28 Avg length: 340,7 Avg pI: 7,48
Protein ID Length (AA) pI
8Lr6h 355 6,98031
7zTgH 312 5,82693
7zb98 312 4,74955
8Lr7s 351 9,02005
8Lv2i 322 5,28389
frVF 284 7,02021
A0A3G2KET2 355 6,98031
A0A0U4IDK0 312 5,82693
A0A3G2KCX9 348 7,71586
A0A3G2KH20 351 9,02005
A0A5Q2WE31 322 5,28389
A0A3G2KF58 352 7,26382
A0A3G2KFA3 352 7,24182
A0A3G2KHG7 352 7,26382
A0A3G2KHX0 352 7,26382
A0A3G2KIR8 355 7,28525
A0A6B9J731 328 5,63970
A0A7L8ZFF4 345 8,26241
A0A7M1CKJ1 345 8,23972
A0A890V2V4 353 9,00038
A0A977PSQ5 346 8,89388
A0A9E7IPT4 346 8,74754
A0A9E7QGX8 347 7,13093
A0A9E8M847 345 7,69483
A0AA96GUM7 346 8,73838
A0AA96GYL0 346 8,74754
A0AA96H8S3 353 9,01089
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_7405
4FizF
 295 32,5% 246 4.836E-25
2 phalp2_37674
4urEs
 29 34,6% 228 9.576E-24
3 phalp2_19071
1jII3
 225 32,2% 248 1.394E-22
4 phalp2_11030
4TmCr
 48 30,7% 241 2.875E-20
5 phalp2_15221
Q1Wv
 34 27,1% 254 1.023E-17
6 phalp2_405
7s6jr
 4 26,1% 287 3.291E-17
7 phalp2_12687
23UHV
 1 25,4% 228 1.571E-05
8 phalp2_10181
tumu
 1 24,7% 238 2.615E-04

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 8Lr6h (355 AA)
Member sequence: A0A977KPR5 (353 AA)
1 355 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Arthrobacter phage Renna12
[NCBI] 		2937734 Andrewvirus >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP297552 [NCBI]
CDS location
range 16914 -> 17975
strand +
CDS
ATGATTCTTTCCAACCTAGCGGCGAAACTCCGCAAGCATGGGCTGACGGTGGTCGAGACTCCGGGGTGGGCGAACCGCGGGTTCCTGGGCCGGGACCTCCTCGAGGTCCGCGGCGTGCTCTGGCACCATACGGCGACTAACCGGTCGCGGTTCGCGAGCTCTCCGGCCCCGACTTTGGGCATGTGCATTGAGGGCCGGCCGGACGTCGCCGGGCCGCTGTGCAACATCGTGTTCGGCCGGGACGGTGCGGTGTACCTTGCCGCTGCCGGGCTCGCTAATCATGCCGGCGCTGGGGCTGCTCCGAACATTCCGCGGGACCTCGGCAATTACTACCTGATTGGCATCGAGATGGAGTCCTCCGGGATTGCTCCGTGGGACTGGTCGCCGGACCAGCTGCGGGTCGCTCCGTACCTGGGCGCGGCGCTCGAGCGTGAGTACCTGATGCACTTGCCGCCGGAGCTGCGGCTGCAGATAGGGCACAAGGAGTATTCGAGTACGGGCAAGATTGATCCGGCCGGCTGGCCGGGGGATATGGACGGGCTGCGGGCGTCCATCAATAAGGTCCTCGCCGGGGGCGGGACCGTCAAGCCGGCGTCGAGCGGCGGCAGCAAGCCGGCCCCTGCTCCGGCCCCGAAACCAACGACGAAGGGCGAACAAGTGCCGAAACATACGCGGCTTTATCCTCCGGCGGTCAAGCGTCGGCTGGCTCCGGGGGCTGAATGGTTCCTCAAGGACAAGACGGGGAAAATCAACCTGAACCTCGCCGGCGGTACCGGCGGGCTTGGGCACTACGACGTGGACCTGTTCGTGCAGGGCTCCGGCCTGGCTGCGGGTGAGGTCGTGGAGGTCCAGTTCTATGTCGTCAAGCCGGGCAAGAAGCCGTCCGGCTACTTTACGCAGCAGGTTCATGGGTCGGCGTCCGGCGAGTTCAAGGGCCGGGCGCGGTTCAAGATGCCGCTGCTTGAGTCCTGCCGCGTCGAGGTCGGCGTGAAGTCCTCGGCGTCGTGTTTCCTCGAGGTCTACGGCGCGGACGTTTACAACTGGCAGAAGGAGGGTAAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8Lr6h) rather than this protein.
PDB ID
8Lr6h
Method AlphaFoldv2
Resolution 88.16
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50