Protein

Protein accession
A0A976UFF7 [UniProt]
Representative
5hSvO
Source
UniProt (cluster: phalp2_4823)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSGAVWPNGSKDRPLISREYGFRSNIYSGGIHKGIDTVGHTYNHAPEDGRVIYAGYNGQYGNEIRIQGVSGKIHRLGHHKSGGMYVSAGQNVSKGQRIGVQGATGMVTGVHCHWEVRTGGADGSHQDPHAWVNAMIASEVTANVGAGQRTAGSGGVKRRSQPTSQSAEAGEWLSPGTVGNFTGWIRGENVNGNDVWYQGTSGHWFWSGGFNEGANGTGLKDLNQVALAGNQRKVVSTGSSNRRGEPTTASPVKDGPLEPNEIGNFNGWKRGESVNGNDVWFRGTSGDWFWSGGFTDTGTHDLEDLNPKTPALKPNHRVVLSDDIANRRTEPKTSAPLAGDAFPAGTIHEFDLWTRGDSVSGNDVWFRHIPSESWSWSGGFEGGAKTDGLTEKKATVPTPEPTPTAAERTVLADASVNGRTGAGTTFALSGSLDAGSKHTFNAWAAGESVNGISTWFRLPDNRWFWAGGFTSQSTDGLTKVDVPKPPSNQLDTSYKTFKADSKLAKWIGSPNYNWRTPRAANEKPRHITMHWFGTANPKLKDTDNHFQTYGTLVNGRGDGTASNYAVGSGEIHQYIREQDYQQADGNQDSNRYGISIEHEAGPSKPPTAETIELSAQLMADIAERYGWKQLTWMVNVFPHSNWTATQCPGTLPTAQIITRANQILANITDPEPQPEPEPSDDLTDLRNAWSVFKSKMDEYLS
Physico‐chemical
properties
protein length:701 AA
molecular weight:75984,3 Da
isoelectric point:6,27
hydropathy:-0,71
Representative Protein Details
Accession
5hSvO
Protein name
5hSvO
Sequence length
298 AA
Molecular weight
32475,60130 Da
Isoelectric point
9,05718
Sequence
MGAFWPNGSKTNKPRRTREFGYRSSIYKRGWHTGWDTAGYPRNHVPERGVVERCYYDGSYGNTVLVRHHDGVVSRTAHGAPGGFLVSPGQIVEDGQALLVQGTTGMSTGVHNHEEIILPDGTFVDPEQWIANRGEAPAPAPAAGGNPLGYFDVPADSQYYYWHYGNALIGNYASNQYLRGGQTLAVVENPGTGPVRVRAADGDLVWVGTRKNPARVRPGAAPAPAAKRHLFDVPAGGQYWYSKYENALAGNYDASQIMHGGTREVVEDPGTGPVRIRANDGSLIWVGTRRNPARTYWA
Other Proteins in cluster: phalp2_4823
Total (incl. this protein): 5 Avg length: 384,2 Avg pI: 7,95
Protein ID Length (AA) pI
5hSvO 298 9,05718
75ErG 320 6,21304
7yfC5 298 8,86900
fwkx 304 9,32034
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12808
8fpv4
 1 28,3% 296 1.785E-32
2 phalp2_12453
t635
 9 34,7% 213 5.859E-26
3 phalp2_13843
7k2Ej
 3 33,0% 200 4.678E-23
4 phalp2_21666
35eEp
 2 23,8% 289 7.867E-18
5 phalp2_11336
7m67S
 15 27,6% 257 2.500E-13

Domains

Domains [InterPro]
PET_M23
Unannotated
Unannotated
Representative sequence (used for alignment): 5hSvO (298 AA)
Member sequence: A0A976UFF7 (701 AA)
1 298 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Microbacterium phage Cece
[NCBI] 		2972516 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
OP068343 [NCBI]
CDS location
range 103181 -> 105286
strand +
CDS
GTGAGCGGCGCAGTTTGGCCTAACGGTTCCAAGGATCGCCCGCTCATCTCTCGCGAGTATGGCTTCCGATCCAACATTTACAGCGGTGGTATCCACAAGGGTATTGACACCGTTGGTCACACCTACAATCACGCCCCTGAAGATGGTCGAGTAATCTACGCTGGCTACAACGGTCAGTATGGTAACGAGATTCGCATTCAGGGCGTCAGCGGCAAGATTCACCGCCTCGGTCACCACAAGAGCGGTGGCATGTACGTCAGCGCCGGACAGAACGTCTCCAAGGGCCAGCGCATCGGCGTCCAGGGCGCTACCGGTATGGTTACCGGCGTGCACTGCCACTGGGAGGTCCGCACAGGGGGCGCAGACGGCTCACACCAGGACCCGCACGCCTGGGTCAACGCCATGATCGCCTCGGAGGTTACCGCGAACGTCGGTGCCGGTCAGCGTACCGCAGGCTCGGGTGGCGTCAAGCGCCGCAGCCAGCCCACGTCTCAGAGTGCTGAGGCGGGCGAGTGGCTGTCTCCGGGTACGGTCGGCAACTTCACCGGCTGGATTCGCGGTGAAAACGTCAACGGCAATGATGTCTGGTATCAGGGTACGTCCGGTCACTGGTTCTGGTCGGGTGGATTCAACGAGGGTGCAAACGGCACCGGTCTGAAGGACCTCAACCAGGTCGCCCTTGCAGGCAACCAGCGTAAGGTCGTCTCGACTGGCTCCTCGAACCGTCGTGGCGAGCCTACCACAGCTTCGCCCGTCAAGGATGGACCTCTGGAGCCGAACGAAATCGGTAACTTCAATGGCTGGAAGCGCGGAGAAAGTGTCAACGGGAACGACGTATGGTTCCGTGGCACCTCGGGCGACTGGTTCTGGTCGGGTGGATTCACCGACACCGGCACCCACGACCTCGAAGACCTGAACCCGAAGACCCCGGCACTGAAGCCCAATCACCGTGTTGTTCTGTCGGACGATATCGCTAACCGCCGCACCGAGCCGAAGACCTCTGCACCCCTCGCAGGCGATGCGTTCCCCGCAGGAACTATCCACGAGTTCGATCTGTGGACTCGGGGCGATTCCGTCTCCGGAAATGACGTGTGGTTCCGTCACATTCCTTCCGAGAGCTGGTCCTGGTCGGGCGGCTTCGAGGGTGGCGCAAAGACGGACGGTCTGACCGAGAAGAAGGCGACCGTTCCGACCCCTGAGCCTACCCCCACCGCCGCTGAGCGTACCGTACTCGCGGACGCCTCGGTGAATGGTCGTACCGGCGCGGGCACCACCTTCGCGCTGTCTGGATCGCTGGATGCGGGCTCGAAGCACACATTCAACGCCTGGGCTGCGGGTGAATCGGTGAACGGAATCTCCACGTGGTTCCGCCTGCCGGACAACCGCTGGTTCTGGGCCGGTGGCTTCACCTCACAGAGCACAGATGGACTGACCAAGGTCGATGTGCCTAAGCCGCCGAGCAACCAGCTCGACACCAGCTACAAGACGTTCAAGGCGGACAGCAAGCTCGCCAAGTGGATCGGTTCTCCGAACTACAATTGGCGCACTCCTCGTGCCGCCAACGAGAAGCCGCGTCACATTACGATGCACTGGTTCGGCACCGCCAACCCGAAGCTGAAGGACACGGATAACCACTTCCAGACCTACGGCACGCTTGTCAACGGTCGTGGTGATGGTACCGCATCGAACTACGCTGTCGGATCGGGTGAGATTCACCAGTACATCCGCGAGCAGGACTACCAGCAGGCGGACGGTAACCAGGATTCCAACCGCTACGGCATCTCCATCGAGCACGAGGCTGGCCCCTCCAAGCCCCCCACGGCGGAAACCATCGAGCTGTCCGCACAGCTCATGGCTGACATCGCGGAGCGTTACGGCTGGAAGCAGCTCACCTGGATGGTGAACGTCTTCCCGCACAGCAACTGGACAGCCACGCAGTGCCCGGGTACACTACCCACGGCGCAGATCATCACCCGTGCCAACCAGATTCTGGCGAACATCACAGACCCGGAGCCGCAGCCCGAGCCTGAGCCGAGCGATGACCTCACGGACCTCCGCAACGCCTGGTCGGTGTTCAAGTCCAAGATGGATGAATATCTGTCTTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5hSvO) rather than this protein.
PDB ID
5hSvO
Method AlphaFoldv2
Resolution 85.53
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50