Protein

Protein accession
A0A8S5VIZ9 [UniProt]
Representative
8sXPL
Source
UniProt (cluster: phalp2_902)
Protein name
Lysozyme family protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MEHISYIPFKTIKKIEIYINSKKMSLTEIVKQTGCDYAITGVFYNTSWKPTCHLKKDGKVLATDPSVYRGFCWNQGPDFNQRRVPTEASGFDNYLACCTLIANGNPYPNNLVIYNKDVGGTRGRTGIGIKGTNLVLYASKDGTSDAKTPERLRDYMYTKGVTEFIMGDGGGKVNFYGDGAIMQGVSKSQNFVLVYLNKHGDKKEDTTPSQNTQTNETPENEFAIIQSPIANNLRYKAHQTKAKYGYMQHSTGTPGAKASNFIKYWNSQSAQAETEFIIDDTGIYQMMPIGIRTWHCGGSANNTHVGCEICEPIGARLLDVNWKALSQGSANNTTYAVTLLQKELTAQGFNTNGIDGVFGNGTKVAVVAFQKKNGLTADGIVGLGTLHALQKREGSYLLYNIKENQAYFEGVYRKAVYTCAYVLRQMGQKTIDKNIVLSHAEGHSMGIASGHADVGHWFPKHGKTMDDFRADVKEYMASEKLPYDKVTETKPTESTKPTVEPEKDEMAFAWNKACDMGIFDGTNPTGVVTRRQLAVVLNRLNLLK
Physico‐chemical
properties
protein length:544 AA
molecular weight:60211,5 Da
isoelectric point:8,79
hydropathy:-0,47
Representative Protein Details
Accession
8sXPL
Protein name
8sXPL
Sequence length
322 AA
Molecular weight
35562,89520 Da
Isoelectric point
8,00983
Sequence
MLSSFIILRSKVMEYTITQSLLTKNPRYTNQRKKAKTAYMQHSTGAPGAKASRFLASWNSTSCQAEAEFIIDDTGIYQCLPIGIRAWHCGGTGNNTHVGCEICEPENARMLDANWLALSQGGKNNTTYAVTMLQKELYAQGYDPKGTDGNFGPGCKAAVIAFQKDHKLTPDGSVGLATLHELQKREGSYLSYNIKENQAYFEDVYRKAVYTCAYVLSEIGQKNIDKNTVCSHAEGYKLKIASNHADVAHFFGPHGKTMDDFRDDVKAYIETGVLPYSKAETKPIDLVWTKAQKLGLFKDIEQSDALTAGDLASALNTLNLLK
Other Proteins in cluster: phalp2_902
Total (incl. this protein): 11 Avg length: 324,9 Avg pI: 8,29
Protein ID Length (AA) pI
8sXPL 322 8,00983
3toFR 301 8,90884
60BiF 301 8,96318
69fS7 301 9,06936
6q3B1 301 7,65481
7WE4L 301 8,88440
7YEXa 293 5,67324
8bYf0 302 8,90806
8tTwz 301 7,64401
A0A8S5RRN9 307 8,70969
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23011
3Pylt
 316 29,3% 259 4.498E-30
2 phalp2_39586
6nEZG
 27 30,0% 270 1.282E-28
3 phalp2_35488
tqvH
 739 28,0% 285 1.737E-28
4 phalp2_36672
45lpM
 229 25,1% 294 2.084E-21
5 phalp2_13982
kgnW
 11 22,6% 256 4.606E-11

Domains

Domains [InterPro]
PG_1
Representative sequence (used for alignment): 8sXPL (322 AA)
Member sequence: A0A8S5VIZ9 (544 AA)
1 322 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471|PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Herelleviridae sp
[NCBI] 		2831613 Herelleviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK035230 [NCBI]
CDS location
range 29206 -> 30840
strand -
CDS
ATGGAACATATTTCTTATATTCCTTTTAAGACAATCAAGAAGATTGAAATTTATATTAACTCTAAGAAAATGTCCCTGACAGAAATTGTTAAACAGACTGGTTGCGATTATGCCATTACAGGCGTTTTTTACAATACGTCATGGAAGCCAACTTGCCATCTAAAAAAGGATGGTAAGGTATTGGCTACTGACCCATCTGTTTATAGGGGTTTTTGCTGGAATCAAGGCCCTGATTTCAATCAACGTAGAGTGCCAACAGAAGCAAGCGGATTTGATAATTATCTCGCTTGTTGCACATTGATTGCTAATGGCAATCCTTATCCAAATAATCTTGTTATTTATAATAAAGACGTTGGTGGCACTAGAGGTCGTACAGGTATAGGTATCAAGGGGACTAATCTTGTGCTGTATGCGAGCAAGGATGGCACAAGTGATGCAAAAACGCCTGAAAGACTAAGAGATTATATGTATACTAAAGGCGTTACAGAGTTTATTATGGGCGATGGTGGAGGTAAGGTCAATTTTTATGGCGATGGTGCGATAATGCAAGGTGTGTCTAAATCACAGAACTTTGTACTTGTCTATCTGAATAAACATGGGGATAAGAAAGAAGATACTACACCTAGCCAAAACACACAGACAAACGAAACACCAGAGAATGAATTTGCTATTATTCAGTCGCCTATCGCTAATAATCTACGTTACAAAGCTCACCAGACTAAGGCTAAATATGGCTATATGCAACATAGTACAGGCACTCCCGGAGCAAAAGCCAGTAATTTTATCAAGTATTGGAATAGCCAGTCTGCTCAGGCTGAAACAGAGTTTATTATTGACGATACTGGTATTTATCAAATGATGCCTATTGGTATCCGAACATGGCATTGTGGTGGTAGCGCCAATAATACCCATGTGGGGTGTGAGATTTGTGAGCCTATTGGGGCAAGGCTACTTGATGTTAATTGGAAGGCATTAAGTCAAGGTAGCGCAAACAATACTACTTATGCTGTAACGCTATTGCAGAAAGAACTTACTGCGCAAGGGTTTAATACTAATGGTATTGATGGTGTGTTTGGCAATGGAACCAAGGTCGCAGTTGTGGCGTTCCAGAAAAAAAATGGCCTGACTGCTGATGGAATCGTAGGACTTGGCACACTACACGCCCTGCAAAAACGAGAAGGCTCTTATTTGCTCTATAATATCAAGGAAAATCAGGCTTATTTCGAAGGCGTTTATCGCAAGGCCGTTTATACCTGTGCTTATGTTTTAAGGCAAATGGGGCAGAAAACTATTGATAAAAATATAGTCCTTTCACACGCAGAGGGGCATAGTATGGGTATCGCAAGCGGTCATGCTGATGTGGGGCATTGGTTCCCTAAGCATGGCAAGACAATGGATGATTTCAGGGCCGATGTAAAGGAGTATATGGCTAGTGAAAAGCTACCTTATGATAAGGTAACTGAAACTAAGCCCACTGAGTCAACTAAACCGACTGTCGAACCTGAAAAGGATGAAATGGCCTTTGCTTGGAATAAGGCTTGCGATATGGGTATTTTTGATGGTACTAATCCAACAGGTGTTGTTACTCGTAGACAGCTTGCTGTTGTTTTGAATAGATTAAATCTATTGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8sXPL) rather than this protein.
PDB ID
8sXPL
Method AlphaFoldv2
Resolution 93.09
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50