Protein

Protein accession
A0A8S5VIK8 [UniProt]
Representative
5SXpu
Source
UniProt (cluster: phalp2_11187)
Protein name
Morphogenesis protein 1 hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MRLSNGEVLLRWPLDIHVLTQGWYYNDGSLHQAADWRTQNGTDYKRPVYAAEDGTVDQVQDWDGHTKTGMQSYGNMVRIKHDPYKGKTLQTRYAHLSSYCVKYGQRVKEGEIIGFSGVTGNVYGAHLHFEVILGGKRTNPLTWLDNDYTLATGREYQFNKGEHSVVVPEADKPAENTSQSKLQVITIGPVSQGDADAIYLLCKERNLTDAGLYKSEWAEV
Physico‐chemical
properties
protein length:220 AA
molecular weight:24802,3 Da
isoelectric point:6,05
hydropathy:-0,63
Representative Protein Details
Accession
5SXpu
Protein name
5SXpu
Sequence length
350 AA
Molecular weight
38811,28730 Da
Isoelectric point
5,15492
Sequence
MEKSLERIDTINAEITALKSLLTDTDYKALKHADGVMSAEEYEPIRQQREEWRDKINALETELATATQEFDAEMAKMAAEDMRLSNGEVLLCWPLDIHILTQGWYYNNGSLHQAVDLRTQIGANYKRPVYAAEDGTVDQTQDWDGRTKTGMQSYGNMVRIKHSPYKGMTLQTRYAHLSSYCVKYGQQVKEGDIIGYSGITGNVFGAHLHFEVILNGKRTNPLTWLDGDYTLATGKEYQFNKGEHSVVIPDADKKPAASPAETPSTALAAEEGKTIQAMLIGPLTAAEAAAFDAMAVESGLADDRYVKLAVDTEGKTFMRAATLTGIDAMRMYALAQTKGLKDKYFSEYVG
Other Proteins in cluster: phalp2_11187
Total (incl. this protein): 21 Avg length: 266,7 Avg pI: 6,25
Protein ID Length (AA) pI
5SXpu 350 5,15492
2l4ks 262 6,23765
3lk9V 269 6,44716
5Nesr 269 6,16660
5OI3q 269 6,23975
5TpDH 269 6,44681
60uk1 269 6,44772
62n2L 269 6,71060
64UkK 262 5,82733
6crlI 269 6,24310
6dVwO 269 6,44687
6fp3w 269 6,23969
6kEh0 269 6,06213
6l1NV 269 6,24009
6mfSf 269 6,06469
6rGP3 269 6,30296
6wi82 269 6,24191
8sEpG 269 6,70765
A0A8S5V299 254 7,12888
A0A8S5VJZ0 217 5,87865
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_12764
88ocX
 115 64,4% 225 4.448E-100
2 phalp2_13327
3V0BV
 5 29,8% 248 1.863E-14

Domains

Domains [InterPro]
Unannotated
PET_M23
Unannotated
Representative sequence (used for alignment): 5SXpu (350 AA)
Member sequence: A0A8S5VIK8 (220 AA)
1 350 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Ackermannviridae sp
[NCBI] 		2831612 Ackermannviridae >
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK035229 [NCBI]
CDS location
range 14048 -> 14710
strand +
CDS
ATGAGATTATCGAACGGGGAAGTTTTACTCCGCTGGCCGCTGGACATTCATGTGCTGACGCAGGGGTGGTACTACAACGACGGCAGCTTGCATCAGGCCGCCGACTGGCGCACGCAGAACGGCACGGACTACAAGCGCCCGGTCTACGCGGCAGAGGACGGCACGGTTGACCAGGTGCAGGACTGGGACGGCCACACAAAAACCGGGATGCAGAGCTATGGCAACATGGTGCGCATCAAGCATGACCCCTACAAGGGAAAGACTTTACAGACGCGGTACGCGCACCTGAGCAGCTATTGCGTCAAGTACGGCCAGAGGGTCAAAGAGGGTGAGATCATCGGCTTCAGTGGCGTGACCGGCAATGTGTACGGCGCTCACCTGCATTTTGAGGTCATTCTGGGCGGCAAGCGCACCAACCCACTGACCTGGCTGGACAATGACTATACCCTTGCCACGGGCCGGGAGTATCAGTTTAACAAGGGCGAGCATAGCGTTGTTGTGCCGGAGGCTGACAAGCCTGCCGAGAATACGAGCCAAAGCAAGCTGCAAGTCATCACGATCGGCCCGGTATCACAGGGAGATGCAGACGCAATTTATCTGCTGTGCAAGGAGCGTAACCTGACGGATGCCGGGCTGTACAAATCTGAATGGGCGGAGGTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5SXpu) rather than this protein.
PDB ID
5SXpu
Method AlphaFoldv2
Resolution 83.93
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50