Protein

Protein accession
A0A8S5UEJ0 [UniProt]
Representative
3VJ9A
Source
UniProt (cluster: phalp2_31507)
Protein name
PGRP protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MDLFECLHTRCRCYKANARGQYKPSPVAGIVVHSTGANNPYLRRYVQPSSEDKNYNALIKKIGKNINGNSWNNPVSETCVHAFIGRLANEKVGTAQILPFDFACWGCANGKNGSYNYAPTRHIQFEICEDNLKDKGYFDRVVKTEAVDFCAYLCKTFNLDVSKIVSHKEAHDLGYASNHGDLDHWLNKFGYNMTDFRSWVSKKIKEEDKKNMIEFKVKSGEVMTKKLLDAPAELRSRADDKKGSVISVLPAGAEVSLIQPDILGYDCVFCVISNKKYIGYIKSEYIE
Physico‐chemical
properties
protein length:287 AA
molecular weight:32439,6 Da
isoelectric point:8,62
hydropathy:-0,45
Representative Protein Details
Accession
3VJ9A
Protein name
3VJ9A
Sequence length
512 AA
Molecular weight
57721,08450 Da
Isoelectric point
6,15540
Sequence
MKYSESNKPISCIMTNSTCYKAHQSFAPRGILIHSTGANNPYIKRYVQPSDDDPDKDRLLSVLGVNSNHNDWNHIYREAGVHAFIGKLANEEIATVEAIPYNIKPWGCGSGKRGSCNEGWLQFEICEDSLNDNVYFNKIYNEMIEYISYLCVKFNLNPEGFVNMSGVNVPVITCHAEASQLGYASNHADILHWFPKFGKSMANIREDVKALISQGVVITPDNKGEAKEEPAESVEMNESNQSSKQEETSSQSQATASSPIPMPNTERYIWDILMKVFDNEYAVAGIEGNLKAESNLRSNNLQNSYESKLGMTDEEYTAGVDSGLYNNFVRDSAGYGLAQWTYWSRKQGLLERAKAQGVSISDISMQLSYLIDEIKANKSLFNELRDVSTVGRASYLILTQYEKPADQGKNQQLKREKLSLYFYNEFSSKKPSEVVKETQPTGEVRFRAGDKVKLTNEPAYASSQDKTRYSSKSGVFYLWDDKVINRRIKITTKKEFVGIRGKVTCWVAINNL
Other Proteins in cluster: phalp2_31507
Total (incl. this protein): 7 Avg length: 468,1 Avg pI: 7,89
Protein ID Length (AA) pI
3VJ9A 512 6,15540
21OSq 511 8,76701
21PtT 515 8,07907
3PDX3 527 8,79789
3nLlj 379 8,92167
41dnM 546 5,89201
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_16386
5LJUU
 43 44,9% 485 5.136E-196
2 phalp2_6756
411nT
 12 43,8% 474 3.391E-171
3 phalp2_12879
2os0g
 1 35,0% 496 1.866E-107
4 phalp2_17251
3TIE6
 53 31,9% 376 1.203E-71

Domains

Domains [InterPro]
Unannotated
Phage_lys2
Unannotated
Representative sequence (used for alignment): 3VJ9A (512 AA)
Member sequence: A0A8S5UEJ0 (287 AA)
1 512 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF18013

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctjVy23
[NCBI] 		2825271 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK016074 [NCBI]
CDS location
range 1346 -> 2209
strand +
CDS
ATGGATCTTTTCGAATGTTTACATACTCGCTGCCGTTGCTATAAGGCAAATGCGCGCGGACAATATAAGCCGTCCCCTGTGGCGGGGATAGTAGTGCATTCCACGGGCGCGAATAATCCGTATCTCCGCAGATATGTGCAACCGTCGAGCGAGGATAAAAATTACAATGCGCTCATAAAAAAAATAGGCAAAAACATAAATGGCAACTCATGGAATAACCCCGTTAGTGAAACGTGCGTTCATGCCTTTATCGGCAGACTTGCAAACGAAAAAGTCGGAACGGCACAAATATTGCCTTTCGACTTTGCTTGCTGGGGCTGTGCAAATGGAAAGAACGGATCTTATAACTATGCTCCGACGCGTCATATACAGTTCGAAATTTGCGAAGATAATTTAAAAGACAAGGGATATTTTGATCGCGTTGTAAAAACCGAAGCCGTTGATTTTTGCGCATATCTTTGTAAAACCTTTAACCTTGACGTATCAAAAATTGTATCGCATAAAGAAGCGCACGACCTCGGTTACGCGTCAAATCACGGAGATCTTGATCATTGGCTTAACAAATTCGGCTATAATATGACCGATTTTAGATCGTGGGTATCAAAAAAAATTAAAGAGGAAGATAAAAAAAACATGATAGAATTTAAGGTAAAAAGTGGAGAAGTAATGACAAAAAAACTTCTTGACGCTCCCGCAGAACTCCGCAGCCGTGCGGACGATAAAAAAGGATCAGTTATTTCTGTGCTGCCCGCAGGCGCAGAGGTATCACTTATACAGCCGGACATACTCGGATACGACTGCGTTTTTTGCGTAATATCAAATAAAAAATATATCGGATATATAAAATCTGAATATATCGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3VJ9A) rather than this protein.
PDB ID
3VJ9A
Method AlphaFoldv2
Resolution 85.46
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50