Protein

Protein accession
A0A8S5U1I8 [UniProt]
Representative
1Nyjf
Source
UniProt (cluster: phalp2_11680)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 97% (predicted by ML model)
Protein sequence
MKFTPRTTAPTKNNKCYYSNNNRYYLNGYGLPNCTCYAYGRILELIGYIPNGLHYGNAENWYPNTKSLEKGQTPKLGSIICFKGNKGHVAVVEKIYEDGSIDISNSAYKGTLFYMKHLKNDYKYNDKYKFQGFIYLPIKFENDTPKISFKTGQIVRLSESATEYQGSSKGIKIPNNYKNKTYTILQVSKDEQTILLKELYSWVLASECSIVEQKKEVKYKVNALLGLWMLNSNGKKVKVYRKGTIVTYLGYGYSKYGYTYYKVKIDNTNQVGFMASKFLIKQ
Physico‐chemical
properties
protein length:282 AA
molecular weight:32501,0 Da
isoelectric point:9,54
hydropathy:-0,57
Representative Protein Details
Accession
1Nyjf
Protein name
1Nyjf
Sequence length
171 AA
Molecular weight
19720,79140 Da
Isoelectric point
4,72431
Sequence
MFIPRLTDDGMMGNKYWYDTNYNPYYPDYGLPNCTAYCYGRGWEVMQGNDPELPMGNAEEWADRTTYPVGSTPRLGSILCFAYADAGHVASVEIINEDGSIVVSNSAWQGTYFWIETLYPEDNYRPSWADNYDFRGFIYLPIPGPTPPTPTDFSKKKDSLVRRWCKHRCWA
Other Proteins in cluster: phalp2_11680
Total (incl. this protein): 74 Avg length: 182,6 Avg pI: 7,34
Protein ID Length (AA) pI
1Nyjf 171 4,72431
17jrN 231 9,48519
1cMfr 157 6,03496
1kxX 179 7,67613
21y3C 185 6,29403
236iL 194 4,43216
23Jur 177 6,71896
24Dlm 182 5,93970
2lTr4 196 9,17329
38Nvw 187 9,13216
3GOX2 175 8,62621
3GPuk 189 9,24111
3TPUu 176 6,80217
3VM0j 208 7,65061
3VMGp 176 5,61645
3ZTsD 214 6,26146
3dQPr 171 8,53299
3dWrD 165 6,71635
3e0kQ 220 6,49212
3gIPq 182 5,73326
3gdHV 186 5,35772
3w1HQ 218 4,25232
3x7pL 192 9,29861
3yUH1 176 8,64574
4L48y 179 7,64515
5LWyz 181 5,25536
5LdwV 174 5,56951
5NhxK 189 9,24111
5OZ4T 184 8,64355
5Ot8X 181 5,53478
5SnRP 195 8,91483
5T0Cr 181 6,70140
5TOrP 194 7,58456
5UA2L 194 6,06435
5ZG3m 175 7,65248
621w5 172 9,17393
629IN 181 5,26951
62bsc 172 9,29913
63KRa 172 6,70992
643EB 163 8,33262
65WFy 181 7,57024
67Aui 161 6,81343
67YQe 160 7,66311
68cpE 174 5,56951
69Dzl 163 8,84740
6b3r1 181 5,61986
6giZO 175 8,83560
6iylQ 181 5,26286
6kQpp 181 7,57064
6mpMy 175 8,93733
6oFau 174 5,22665
6one0 175 8,83560
6q1vO 194 7,58524
6rFso 175 7,67130
6sLv5 178 8,52951
6vA9G 175 8,62621
6wAVW 194 8,27286
6wGhW 175 8,62621
7XkrL 178 8,51545
7Yoms 173 5,83949
7Z76S 161 7,63731
83A9O 178 8,53073
85EXb 194 6,70344
8deet 177 8,60119
8dhX8 175 7,79566
8fAyN 177 5,56393
8hs8x 175 7,64890
8nPRH 192 9,17329
8oQfz 192 9,15659
8pAqg 172 5,88439
8rLw9 175 8,31495
BOHv 175 6,88533
b4Zh 172 4,68640
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_18807
1gBg7
 77 40,9% 154 7.039E-48
2 phalp2_4896
5TGNK
 9 40,2% 149 1.855E-44
3 phalp2_10722
3dYCr
 65 37,2% 153 3.622E-38
4 phalp2_40337
3iVXO
 43 36,1% 163 2.394E-37
5 phalp2_25508
3ghnP
 6 42,3% 111 2.683E-35
6 phalp2_3062
21xLs
 8 34,6% 153 4.550E-34
7 phalp2_17558
5WoZV
 75 34,5% 191 2.207E-30
8 phalp2_15440
410GZ
 43 34,4% 177 1.450E-26
9 phalp2_2544
6h4Z7
 13 33,9% 159 9.523E-26
10 phalp2_36602
21saM
 3 32,7% 174 1.303E-25

Domains

Domains [InterPro]
CHAP
Disordered region
Representative sequence (used for alignment): 1Nyjf (171 AA)
Member sequence: A0A8S5U1I8 (282 AA)
1 171 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctt8434
[NCBI] 		2825703 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015983 [NCBI]
CDS location
range 38 -> 886
strand -
CDS
ATGAAATTTACACCAAGAACAACCGCACCAACAAAAAATAATAAATGCTATTATAGTAATAACAATAGATATTACCTAAATGGCTATGGATTGCCAAATTGTACATGCTATGCTTATGGTAGAATTTTAGAACTAATAGGTTATATTCCAAACGGATTACATTATGGCAATGCTGAAAACTGGTATCCTAATACAAAAAGTCTAGAAAAGGGGCAAACACCAAAGTTAGGTTCAATAATATGTTTTAAAGGTAACAAAGGTCATGTGGCAGTAGTAGAGAAAATTTATGAAGATGGTTCTATTGATATTAGCAATAGTGCTTACAAAGGTACTTTGTTCTATATGAAACACTTAAAAAACGATTACAAGTATAATGACAAATATAAATTTCAAGGATTTATCTATTTGCCTATTAAGTTTGAAAATGATACTCCTAAAATTTCGTTTAAAACAGGTCAAATTGTAAGATTAAGTGAAAGTGCTACAGAATATCAAGGAAGCTCAAAAGGAATAAAAATACCTAACAACTACAAAAACAAAACATATACTATACTACAAGTAAGCAAAGATGAACAAACTATTCTTTTAAAAGAGTTATATAGTTGGGTTTTAGCAAGTGAATGTTCTATAGTAGAACAAAAAAAAGAAGTAAAGTATAAAGTTAACGCTTTACTTGGATTATGGATGTTAAATAGTAATGGTAAAAAAGTCAAAGTTTATAGAAAAGGAACTATTGTTACGTATTTAGGCTATGGTTACAGCAAGTATGGATATACATATTATAAGGTTAAGATAGATAATACAAATCAAGTAGGTTTTATGGCTAGTAAATTTTTGATAAAACAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1Nyjf) rather than this protein.
PDB ID
1Nyjf
Method AlphaFoldv2
Resolution 88.77
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50