Protein

Protein accession
A0A8S5TY91 [UniProt]
Representative
5KIac
Source
UniProt (cluster: phalp2_11173)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 91% (predicted by ML model)
Protein sequence
MGTISDVLYCARDWIGYSRWTDPEEGTVFGRWYAEKTGEPYFGTSGVPYCAMFASYCLDWAGVPCAGMPSAYCPDIVNAGEEAGATVSCEDAEPGDLVLFDWGGDGLADHVGIVEDNHPGEGYMTTIEGNTSSGDGGSQSNGGVVARRQRGYGSVRCVVRPDYNENQEEEDMGLTEHQDELLTTIYEQVTSTYDPTGRGMELNDHDHIKWVAKQCADNADYIKAVDAKLDKLIEKLG
Physico‐chemical
properties
protein length:237 AA
molecular weight:25827,0 Da
isoelectric point:4,24
hydropathy:-0,50
Representative Protein Details
Accession
5KIac
Protein name
5KIac
Sequence length
360 AA
Molecular weight
39681,40830 Da
Isoelectric point
4,19451
Sequence
MPTANDVLYCAQQWIDYSRWTDPEEGTVFGRWYAEKTGDSYYGTSGVPYCAMFASYCLDWAGVSAPGMPGAYVPWILDAGYENGTMVYNEDAQPGDLVMFDWGGDGVADHIGIVEENHPDEGWMQTIEGNTSSGTSGSQSNGGGVYRRARSYSSIIGISRPWYGADEEPEEPEAPAEPTPEEIEQARVDGLPEALKKYSDLYPGEWYIACVNSAVEQGLMRGTSDTTFEPYETLTRAMAIAVIANKLKADVEPLPFTDIAEWYTATAIWAEKQGIITGNGGEMRPNDGCTRQEFAVMLWRSQGKPEVDIEPDFEDWGDVADWAQDAMKWAIDKKIIGNGGNLRPNDICSRAECASMATKF
Other Proteins in cluster: phalp2_11173
Total (incl. this protein): 3 Avg length: 318,3 Avg pI: 4,26
Protein ID Length (AA) pI
5KIac 360 4,19451
6v19j 358 4,32831
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_2684
7236j
 6 47,6% 250 9.430E-75
2 phalp2_37209
21s1y
 4 31,6% 231 9.288E-36
3 phalp2_29519
21Fz5
 10 35,0% 240 1.142E-15
4 phalp2_15386
1Nzv3
 2 26,4% 231 1.544E-13

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 5KIac (360 AA)
Member sequence: A0A8S5TY91 (237 AA)
1 360 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctPkm1
[NCBI] 		2825099 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015960 [NCBI]
CDS location
range 21661 -> 22374
strand +
CDS
ATGGGGACGATTAGCGACGTGCTCTACTGCGCCCGCGACTGGATCGGGTACTCGCGCTGGACCGACCCCGAGGAGGGCACGGTCTTCGGGCGGTGGTACGCCGAGAAGACGGGCGAGCCGTACTTCGGAACATCAGGCGTCCCGTATTGCGCCATGTTCGCCTCCTACTGCCTGGACTGGGCTGGCGTCCCGTGCGCGGGCATGCCGAGCGCATACTGCCCCGACATCGTCAACGCGGGCGAGGAGGCGGGGGCAACCGTCTCGTGCGAGGACGCCGAGCCTGGCGACCTCGTTCTGTTCGACTGGGGCGGCGACGGCCTGGCAGACCACGTGGGCATCGTCGAGGATAACCACCCTGGCGAGGGGTACATGACCACCATCGAGGGCAACACCAGCAGCGGCGACGGCGGCTCCCAGTCGAACGGCGGCGTCGTTGCGCGTCGCCAGCGCGGCTACGGCTCCGTGCGCTGCGTCGTGCGACCAGACTACAACGAGAATCAGGAGGAAGAGGACATGGGACTCACCGAGCATCAGGACGAGCTTCTGACGACCATTTACGAGCAGGTGACGAGCACCTACGACCCGACGGGGCGCGGCATGGAGCTGAACGACCACGACCACATCAAGTGGGTTGCCAAGCAGTGCGCCGACAATGCCGACTACATCAAGGCAGTCGACGCTAAGCTCGACAAGCTCATCGAGAAGCTGGGCTAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5KIac) rather than this protein.
PDB ID
5KIac
Method AlphaFoldv2
Resolution 92.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50