Protein

Protein accession
A0A8S5TNK8 [UniProt]
Representative
8r8j6
Source
UniProt (cluster: phalp2_3179)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSVQQSIVNGFTSRRGLITYSMLGSRNGSDGTGDCSGIMSQVLKESGIPIQGLPSTVTLGQQLANNGFYRVSRNQPWDAQMADIILMSWGADMSSSGGAGGHVGAMIDDTYFISCDYSTQGAVGQAINTYPWNDYYSWNKPAYIEVWRYADTAPQTNNQANTSVQPQEKAYYEANEVKYINGIWQIKCDYLAPVGFDWTENGIPVSMVNWVDKDGNNLPDGADQDFKAGMYFSFELDEAHITDTGKGGYYGGYYWRLFEFGQFGPVWISCWDKDDLVNYYS
Physico‐chemical
properties
protein length:281 AA
molecular weight:31301,2 Da
isoelectric point:4,32
hydropathy:-0,43
Representative Protein Details
Accession
8r8j6
Protein name
8r8j6
Sequence length
195 AA
Molecular weight
22188,02500 Da
Isoelectric point
4,10437
Sequence
MSWGDDMSTSGGAGGHVGAMIDDTYFISCDYSTQGAPGQAINTYPWNDYYSWNKPVYIEVWRYADTAPQTNNQANTAVQPKDKAFYQANEVKYINGIYQIKCDYLAPVGFDWTENGIPVSMVNWVDKDGNNLPDGADQDFKSGMYFSFELDEVNITDTGKGGYYGGYYWRLFEFGQFGPIWLSCWDKDDLVNYYE
Other Proteins in cluster: phalp2_3179
Total (incl. this protein): 14 Avg length: 260,4 Avg pI: 4,37
Protein ID Length (AA) pI
8r8j6 195 4,10437
A0A4D6A9R7 243 4,17081
A0A4D6A301 281 4,70550
A0A4D6AV17 281 4,66577
A0A4D6AY45 281 4,55851
A0A4D6A370 281 4,69248
O34082 281 4,50451
A0A3G8F8P1 196 4,21998
A0A3G8FDJ6 195 4,21998
A0A4D6A890 281 4,31490
A0A8S5LKF8 281 4,35162
A0A8S5N9P5 281 4,22344
A0A8S5U065 288 4,19321
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13886
7C1QD
 360 67,7% 192 4.155E-84

Domains

Domains [InterPro]
Unannotated
ZoocinA_TRD
Representative sequence (used for alignment): 8r8j6 (195 AA)
Member sequence: A0A8S5TNK8 (281 AA)
1 195 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF16775

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct7dP4
[NCBI] 		2827787 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032866 [NCBI]
CDS location
range 16263 -> 17108
strand +
CDS
ATGAGTGTACAACAATCTATAGTTAACGGTTTTACAAGCCGTCGTGGGCTGATTACATATTCGATGTTAGGTTCTCGCAACGGTTCAGATGGGACAGGGGATTGCTCTGGTATCATGTCGCAAGTATTGAAAGAATCGGGTATCCCAATTCAAGGTTTGCCATCAACGGTGACACTTGGGCAGCAACTCGCAAATAACGGCTTCTATCGTGTGAGCCGTAACCAACCATGGGACGCTCAAATGGCCGATATTATTCTAATGTCATGGGGTGCCGATATGTCTTCATCTGGTGGCGCTGGTGGGCATGTCGGGGCAATGATCGATGATACATACTTCATTTCTTGCGACTATTCGACACAAGGAGCAGTCGGACAAGCTATCAATACCTATCCTTGGAACGACTACTACAGCTGGAATAAACCAGCTTATATCGAGGTTTGGCGATATGCTGACACAGCACCACAGACAAACAACCAAGCAAACACATCCGTACAACCGCAAGAAAAGGCTTACTACGAAGCAAATGAGGTCAAATACATTAATGGTATCTGGCAAATTAAATGTGACTATCTAGCGCCCGTTGGCTTCGATTGGACTGAAAACGGTATTCCCGTTTCGATGGTAAACTGGGTCGATAAGGACGGAAACAACTTACCAGACGGAGCAGATCAAGACTTTAAAGCCGGAATGTACTTTAGCTTCGAGCTTGATGAAGCTCATATCACGGACACTGGCAAAGGTGGCTATTATGGTGGCTATTATTGGCGATTGTTTGAATTTGGCCAATTTGGACCAGTCTGGATTTCATGTTGGGACAAGGACGACCTGGTGAACTATTATAGCTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8r8j6) rather than this protein.
PDB ID
8r8j6
Method AlphaFoldv2
Resolution 87.43
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50