Protein

Protein accession
A0A8S5TM31 [UniProt]
Representative
7x4iI
Source
UniProt (cluster: phalp2_8240)
Protein name
N-acetylmuramoyl-L-alanine amidase domain-containing protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MKKKITVTAMSLLTALFLLPINGFAYTINNEFNLGVNEGSSQVANNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQSGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSDDKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPKGNTKDGAQDFHDKRWYLNIPKR
Physico‐chemical
properties
protein length:339 AA
molecular weight:38111,9 Da
isoelectric point:6,12
hydropathy:-0,59
Representative Protein Details
Accession
7x4iI
Protein name
7x4iI
Sequence length
207 AA
Molecular weight
23467,78610 Da
Isoelectric point
6,47137
Sequence
LARDSAKKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR
Other Proteins in cluster: phalp2_8240
Total (incl. this protein): 9 Avg length: 231,1 Avg pI: 6,22
Protein ID Length (AA) pI
7x4iI 207 6,47137
71SDi 197 6,52599
76i1l 208 5,96539
7h9RV 230 5,64760
7kw9H 160 6,58459
7uYZG 151 6,39407
A0A8S5NQD3 247 5,15492
A0AAF0MVK5 341 7,16304
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_10524
86QiV
 42 33,1% 223 8.243E-20

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 7x4iI (207 AA)
Member sequence: A0A8S5TM31 (339 AA)
1 207 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctKgQ2
[NCBI] 		2827842 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032853 [NCBI]
CDS location
range 24890 -> 25909
strand -
CDS
ATGAAAAAGAAAATTACTGTTACTGCGATGAGCCTTTTAACGGCTCTTTTTTTATTGCCAATTAACGGGTTCGCCTATACGATCAACAATGAATTTAATTTAGGTGTAAATGAAGGTAGCTCTCAAGTAGCAAATAATCAGTATATTTTACTTCATGAAACGGCTAACGAAACAGCAACAGGACGCAATGAAGCACAGTATATGCAACGTTCATGGACTAGCGCTTATACTGCTTATATTGTGGGAGACGGTGGAATTGTTTATCAAGTCGGACAACCTGGTTATGTACAGTACGGTGCTGGTTCGTATGCTAATGCTAACAGTCCTGTGCAGATTGAGTTACAACACACACATGATAAAGCAACGTTTGAGAAAAACTACAAGGCATACGTTGAATTGGCTAGAGATTCAGCAATGAAATATGGTATTCCATTAACATTGGACACTCCTTATAACCAATCAGGAATCAAATCACATTTATGGGTAACACAAAATATCTGGGGCGATCATACAGATCCTTACGGTTATCTTTCTGAAATGGGCGTAAGTAAAGAAAAATTAGCATATGATTTAGCTCATGGATTTACCGATGAAAATCCGACAACTTCAGATGATAAACCAGTCATTGATCCAACTCGAGCAGGTGCTGCAAATCCTACGCTGACAGATGGAACAAATTACGCCCACATTGATCAGTTCGGAGAAATCGAAAACGCAAACTTGCATGTGGCTGGATGGCACATTGCTAACTATAAATACGAGTATATTTTCATTATGGATTACAATACTGGGAAAGAATTAGCTCGAGTAAGAGCTGATGGAATTTATAGACCAGATGTAAACCAAGCTTATAATACTTCTGGAAATGTTGGTTATCATGTATCTTTCAATATGCGTAATTTTCCTAATAAGAAAGTCTATGTCATGATGCGTGCAACGAATGATCCAAAAGGAAACACTAAAGATGGAGCGCAAGATTTCCATGACAAACGTTGGTATTTAAATATTCCTAAACGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (7x4iI) rather than this protein.
PDB ID
7x4iI
Method AlphaFoldv2
Resolution 85.56
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50