Protein

Protein accession
A0A8S5TM29 [UniProt]
Representative
4VENb
Source
UniProt (cluster: phalp2_5797)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MNYSEFINKYLGKSTDYDGVYGVQCVDLIKAYLHDVFGISAGSWGNARFYWINFNLRAPLKANFNKIKNTAQLVPKRGDIVVWNNTVGNGAGHIAIATGEGDTRSFYSYDQNWNGKPMRKVKHSYSGVYGVLRPKDQSKVAQSSGSTSSASNGSYPTPITWRNGSTPETVYAVNDCTDRIGTVYAKSTAQCYSKAGSCYLIVYSINNGKAHKAGFVAYAGGLNGAPPQSRAWKNGNTSETVYADTAKGTKVGTIDKYESCYCLGKIDGMYLVLYKVNGTNKQKCGFVDYHG
Physico‐chemical
properties
protein length:291 AA
molecular weight:31780,3 Da
isoelectric point:9,33
hydropathy:-0,46
Representative Protein Details
Accession
4VENb
Protein name
4VENb
Sequence length
292 AA
Molecular weight
31817,35530 Da
Isoelectric point
9,17245
Sequence
MMNYSEFVNKYLGKSTDYDGAYGVQCVDLIKAYLHDVFGISAGSWGNARFYWINFALRAPLKANFDKIKNTAQLIPKRGDIVVWNNSVGNGCGHIAIATGEGDTRSFYSYDQNWNGKPMKKVKHTYAGVYGVLRPKDQSKVAQSSGNTSSVSNGSYPTPVTWRNGSTPETVYAVNNCSDKIGTVYAKSTAQCYSKAGSCYLVVYSINGGKAHKAGFVAYAGGLNGAPPQSRAWKNGSTSETVYADTSENTKIGTIDKYESCYCLGKIDGMYLVLYKVNGTNKQKCGFVDYHG
Other Proteins in cluster: phalp2_5797
Total (incl. this protein): 15 Avg length: 287,2 Avg pI: 9,26
Protein ID Length (AA) pI
4VENb 292 9,17245
1khpI 382 9,38474
3k9r4 291 9,22970
3uKAJ 291 9,24594
5QNov 289 9,29165
683Kp 292 9,08290
689Yv 291 9,13377
68PJZ 292 9,26464
6l2j4 292 9,37340
6onNo 291 9,12610
6pP6q 292 9,23311
neRF 283 9,40705
A0A8S5QT20 213 9,13783
A0A8S5QV14 226 9,55662
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_13813
743b2
 10 21,2% 198 1.002E-12
2 phalp2_3981
7wit1
 2 25,2% 194 1.436E-05

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 4VENb (292 AA)
Member sequence: A0A8S5TM29 (291 AA)
1 292 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctTIi48
[NCBI] 		2827875 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032851 [NCBI]
CDS location
range 18008 -> 18883
strand -
CDS
ATGAATTACTCCGAATTTATAAATAAGTATCTCGGAAAATCAACCGACTATGACGGCGTGTACGGCGTTCAATGTGTTGACCTTATCAAAGCTTATCTACACGATGTTTTCGGTATCTCTGCCGGAAGTTGGGGCAATGCCCGGTTCTATTGGATTAACTTCAATCTTCGCGCACCGCTTAAAGCGAATTTCAACAAAATTAAGAACACTGCACAGCTTGTCCCGAAGCGCGGCGATATCGTGGTGTGGAATAACACCGTAGGCAACGGCGCAGGACACATCGCAATTGCCACAGGCGAGGGCGACACGCGCAGCTTCTATTCATATGACCAGAACTGGAACGGCAAGCCGATGAGAAAGGTTAAGCATTCATATTCAGGCGTGTATGGAGTGCTCAGACCGAAAGACCAAAGCAAGGTTGCACAAAGCTCCGGCAGCACTTCAAGTGCTTCAAACGGAAGCTATCCCACGCCTATTACTTGGCGCAACGGCAGCACACCCGAAACAGTTTATGCTGTTAATGATTGCACAGATAGAATCGGCACTGTATACGCAAAGAGCACGGCACAGTGTTACAGCAAGGCAGGCAGCTGTTACTTAATCGTGTATTCGATTAACAACGGCAAAGCGCACAAGGCGGGCTTTGTAGCCTATGCTGGCGGATTGAACGGAGCTCCTCCGCAATCAAGGGCTTGGAAGAACGGCAACACCTCCGAAACGGTGTACGCCGACACAGCCAAAGGCACAAAAGTCGGCACGATTGACAAGTACGAAAGCTGTTATTGTCTCGGCAAGATTGACGGCATGTATCTTGTGCTATACAAAGTAAACGGCACGAACAAACAAAAATGCGGATTCGTGGATTACCACGGATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4VENb) rather than this protein.
PDB ID
4VENb
Method AlphaFoldv2
Resolution 90.83
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50