Protein

Protein accession
A0A8S5T8Y8 [UniProt]
Representative
87KcW
Source
UniProt (cluster: phalp2_10521)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MRNTTDVTDQTASAAGELHHVDQLQLIIKIKKKAMNKIDSIIIHCSATRAGQDLTAKDIDRMHRARGFNQIGYNYVIRIDGTVEKGRSLAVDGAHCNTKGFSESSYNKHSIGICYIGGLDANGKPTDTRTIAQKAALRELVAKLCKEYEIIEVLGHRDTSSDLDGSGEVEPKEYIKACPCFDVRSEFPNFLRNTVVRP
Physico‐chemical
properties
protein length:198 AA
molecular weight:21923,6 Da
isoelectric point:8,18
hydropathy:-0,44
Representative Protein Details
Accession
87KcW
Protein name
87KcW
Sequence length
77 AA
Molecular weight
8847,94400 Da
Isoelectric point
5,65488
Sequence
MKDAIIIHCSATRAEQDITAADIESWHRARGFWTIGYHYVIRLDGTIEPGRDVTLDGAHCMGWILFNPIYVSCYYNQ
Other Proteins in cluster: phalp2_10521
Total (incl. this protein): 27 Avg length: 85,7 Avg pI: 7,71
Protein ID Length (AA) pI
87KcW 77 5,65488
10RJ5 46 10,36428
12tW8 96 5,71677
17B6C 73 8,95835
1Vwd7 81 9,03126
1zRP5 88 8,97550
2UJLs 76 9,06363
2ahFf 99 6,06332
2fHlE 90 5,32413
3DpXp 65 5,06000
3G2bG 84 6,38969
3KWu6 137 5,94902
3ZfPY 79 6,01598
3v69J 79 7,76082
48z4F 50 9,35850
6BhA8 86 9,75163
6OsO9 58 7,95155
7KnAO 78 7,92518
8EuwO 60 9,51935
8GAXd 65 7,78715
8tUOC 94 7,96747
8tqUJ 86 6,14608
Hdm4 68 9,13731
RtiE 137 5,95533
cCzf 88 8,98639
nET0 76 9,09773
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_27898
ipdG
 164 67,2% 61 7.265E-33
2 phalp2_21606
2vySa
 303 50,8% 59 2.497E-24
3 phalp2_9904
2GCXD
 1 52,5% 59 2.684E-21
4 phalp2_4275
7YpR0
 5 44,2% 52 2.474E-16
5 phalp2_25923
64Nde
 24 42,3% 59 2.287E-15
6 phalp2_14978
yv9W
 17 48,2% 56 5.934E-15
7 phalp2_9314
7uSZF
 4 39,7% 73 5.084E-13
8 phalp2_26108
2kvR
 27 37,0% 54 9.603E-13
9 phalp2_37043
NDSw
 22 32,8% 73 1.134E-10
10 phalp2_25454
2YvBT
 2 44,0% 50 6.603E-08

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 87KcW (77 AA)
Member sequence: A0A8S5T8Y8 (198 AA)
1 77 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct3fB6
[NCBI] 		2827770 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032766 [NCBI]
CDS location
range 33343 -> 33939
strand +
CDS
ATGCGGAACACAACCGATGTGACAGACCAGACAGCGAGTGCAGCCGGAGAACTCCACCACGTAGACCAATTACAATTAATAATCAAAATAAAGAAGAAAGCAATGAATAAAATAGACTCGATTATCATTCATTGTTCGGCTACGCGCGCCGGGCAGGATTTAACCGCAAAAGATATTGATCGTATGCACCGGGCGCGCGGATTTAACCAGATCGGATATAACTATGTTATCCGGATTGATGGGACGGTAGAAAAAGGGCGATCTTTAGCAGTTGACGGGGCGCATTGTAATACGAAGGGTTTTAGCGAATCTTCATATAATAAACATAGTATTGGTATTTGCTACATCGGCGGCTTGGATGCAAACGGAAAGCCCACAGACACAAGAACGATCGCTCAAAAAGCAGCTTTGCGCGAGTTGGTTGCTAAACTCTGCAAAGAATATGAGATAATCGAGGTTCTCGGACATCGTGACACTTCGTCGGATTTAGACGGAAGCGGAGAGGTAGAGCCGAAAGAATATATTAAGGCGTGCCCCTGTTTTGATGTACGCTCCGAGTTCCCTAATTTCTTGCGTAATACAGTAGTTCGACCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000aa6e422_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (87KcW) rather than this protein.
PDB ID
87KcW
Method AlphaFoldv2
Resolution 79.98
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50