Protein

Protein accession
A0A8S5T0H0 [UniProt]
Representative
3ZDZv
Source
UniProt (cluster: phalp2_32958)
Protein name
N acetylmuramidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MASKTVSAAEVVALFRRALAEKWGYIWGGTGQVHTQRAQDSATRAQTIRYGQQWVGRRVADCSGLFWWAYKQLGGYMYHGSNTMWRKYAAAKGTLQGGKRTDGQPLKPGTAVFLTKGSDRHHVGLYVGDGKVIEAKGTAYGVVESKITRWNEWAELTGTSYAVDAPDSPADTPDTPAPTENPADAGDGASPLLVLRNGSRGTQVKVLQYLLIDAGFDCGKVDGIVGKNTIAAVKAFQTAHSLTADGIVGAKTWAALLQ
Physico‐chemical
properties
protein length:258 AA
molecular weight:27604,8 Da
isoelectric point:9,33
hydropathy:-0,29
Representative Protein Details
Accession
3ZDZv
Protein name
3ZDZv
Sequence length
284 AA
Molecular weight
31347,90940 Da
Isoelectric point
8,64368
Sequence
MGISPQALIEKFQHALDNKWGYILNTAGEKWTAEKQAKSTNKMTIEYGRQWINHYVADCSGLFAWAFKQLGGYMYHGSNTMYKSYCTSKGTFSNGKRTDGVTLKPGTALFTGTENDRGHVGLYIGGNDVIEAQGTKAGVIKSKADNKKWTWWGELKGVDYGGNVNQGFPEKTGWHPTVRRGMKGDDVRELQSKLYKLGYNLGSYGIDGDFGRATEAAVKEFQEDHKLTVDGVAGPMTWDALDKAVQNVSSKPIEKKYAVCIHGLDKTQADALLTKYPGATCTEE
Other Proteins in cluster: phalp2_32958
Total (incl. this protein): 229 Avg length: 291,5 Avg pI: 7,98
Protein ID Length (AA) pI
3ZDZv 284 8,64368
10CUh 335 5,91162
14Ut9 283 5,45918
14Z44 308 5,49027
1Fmci 253 9,42317
1FyrO 245 4,85907
1HyRh 336 6,02882
1JdSm 347 6,65968
1cLYJ 281 5,12014
1cMfi 290 8,23134
1jC1q 260 8,45446
1lrai 301 6,65530
1o1t5 265 9,11481
21m5N 288 8,44724
21nBi 337 8,74593
21q8d 307 7,81423
21sir 329 8,65432
21ud7 277 7,71154
21weo 272 9,01025
235uL 233 9,38694
238Ah 287 8,83592
23HJd 319 6,11851
23QEy 275 9,37933
23cgf 230 8,91084
23dH7 274 5,21330
23fwX 355 8,70131
23gfc 296 9,09064
23iLj 284 8,72136
23tD6 325 6,95638
23wQg 287 4,87436
23xoM 289 9,31879
24BpS 278 4,90182
2GXY 258 9,34677
2VmbV 349 9,11752
2bpr7 352 8,75959
2dboc 327 8,54253
2fXsF 279 9,52928
2m4Iu 258 9,29939
2o1j3 299 8,37498
33KrT 253 9,25677
38Ht4 287 9,06034
38PcM 314 8,46027
3ITSs 258 9,49679
3PGsp 287 6,34030
3PJFp 270 5,88644
3Q1Ip 354 9,04119
3Q1cc 352 8,83567
3Q3UR 354 8,37362
3TCSP 254 9,18637
3TJ9l 277 7,06568
3TJjX 271 5,64533
3TKY0 341 6,99537
3TPnj 315 5,39933
3TQ85 329 8,77951
3TSbg 299 8,89220
3VEd5 284 8,60210
3VFsg 260 9,20597
3VLVy 230 8,42939
3WAYD 237 6,89976
3WDYt 267 8,72826
3WGDq 234 8,50939
3WGjm 283 7,05505
3WNyW 230 8,45182
3WOpn 356 5,40717
3WyxK 230 8,41868
3Wz6s 264 9,23659
3ZCMz 303 7,56546
3ZEll 277 7,65368
3ZFju 276 9,14170
3ZGiA 354 8,33784
3ZHLE 299 9,11340
3ZJoR 305 8,14985
3ZOGc 282 7,53272
3ZYRu 261 9,02095
3ZrBu 328 8,52718
3ZyhX 302 9,18128
3dQVR 292 9,08619
3dZ2P 289 9,26316
3e2aP 299 5,82619
3e3Qj 300 5,31816
3fVtM 289 6,18791
3g9Hu 352 6,03280
3gI9H 285 4,73386
3gLsd 273 7,68335
3gNXm 289 6,95740
3gVBY 270 9,56977
3gdh0 287 9,00045
3giLM 255 9,01669
3h3ll 285 6,67383
3h7pI 291 9,17309
3iBI7 253 9,53076
3iZMU 308 8,66779
3inYD 281 8,17306
3lTny 258 9,42987
3laqJ 258 9,41130
3mt2j 337 9,37726
3nBNr 354 8,90368
3nJGj 313 8,87080
3nxvb 258 9,51652
3oohC 334 8,35428
3tBqa 258 9,41105
3tm0v 244 8,74535
3ulSJ 258 9,49653
3vNNZ 258 9,51652
3vZGf 339 6,33803
3vhAH 262 9,78245
3w4cU 258 9,24188
3wgcc 258 9,33381
3wj8T 258 9,51652
3wnJb 258 9,51652
3wowL 258 9,49627
3yxYH 258 9,33381
401qR 279 8,70351
405FI 305 6,19741
406c1 300 8,07365
40874 303 6,25561
40905 275 8,71969
4096j 279 7,60980
40Cok 289 6,00103
40XIg 303 5,00026
40Yks 261 9,75279
40a7s 297 7,01003
40aoy 293 8,61570
40bT4 286 8,17190
40lWw 305 8,50166
411Cr 288 8,60719
413sw 314 5,82505
41b3U 284 7,65987
41ejP 355 9,10385
41oHv 269 7,58348
41pDF 292 6,19559
45qiA 307 4,68270
4JXOw 254 9,50685
4K08m 270 5,89479
4L1Gh 346 8,55826
4L2A1 275 4,69828
4L2WQ 279 8,53157
4L2gg 263 8,88537
4Lc2b 285 8,54949
4Og8m 303 6,54520
4OgMx 298 8,81961
4OhQD 302 8,91703
4OhZb 284 9,04480
4W6S3 342 6,54458
4k4n8 272 6,25027
4k4pI 311 8,71563
4k5l0 304 5,27724
4k7X1 286 6,23969
4k7oj 306 6,09612
4k7uF 300 6,83679
4khU7 303 8,02233
4kjs3 308 8,50166
4knpb 283 8,62415
4koxM 304 6,02393
4kpJU 275 8,69583
4kpMt 227 8,58650
5LFAl 258 9,51652
5M25v 258 9,49653
5OyYn 258 9,42987
5P0Rl 337 9,13938
5Pgct 258 9,33381
5Qio2 259 9,17483
5SoIg 261 9,23834
5TK9C 332 6,47938
5UPgb 258 9,41111
5V3fR 337 9,42871
5VdJX 258 9,41111
5q9h 321 7,60207
5zsP 384 8,93559
611x7 258 9,33381
616uW 212 9,88321
61QT7 258 9,42987
61r3r 244 9,01631
63IUU 260 9,07710
63Zlr 244 9,01631
64SGd 246 9,00606
67Qs0 335 8,95970
68zPY 340 8,61286
69Y0l 262 9,22460
6PlMY 344 6,46267
6PsZS 348 6,05644
6UH4A 322 8,99297
6YTRT 258 9,51652
6ZEtC 266 9,38242
6amhZ 334 6,48183
6bNiZ 344 5,96124
6e6Uo 338 9,20217
6fcX3 244 9,11881
6g1jL 258 9,43013
6gAG0 246 8,75431
6idQ8 337 8,97015
6jNre 260 9,08709
6k3UB 339 6,67014
6p8h 343 8,30612
6qVzt 258 9,11236
6skJX 340 8,41849
6twbJ 244 9,01631
6w9lT 256 9,48776
6wFGn 258 9,41130
70qmV 237 9,16697
7DEPg 290 5,75940
7DIDS 313 6,35223
7DKlg 335 8,85997
7DMNb 309 8,13032
7DQHL 293 8,90465
7DR7Q 306 6,76534
7DSRf 346 5,63265
7DTqy 283 8,74547
7OlJW 237 9,16491
7UZF2 334 5,02391
7V0wu 332 5,03448
7ViSu 339 5,71331
7Vm7N 338 5,13622
7WSWn 326 5,77106
7WVqw 331 5,21926
7YWOe 258 9,41105
7YxpC 278 9,00490
80QN 308 6,24106
84gy6 331 5,01720
8e1xf 352 4,77012
8hnsc 334 7,61577
8mgNj 336 9,39841
8n6pP 338 5,12173
8na1y 331 5,13810
8s0W3 334 4,96832
N2HT 258 9,35232
Ow68 258 9,20823
a5mI 290 8,23134
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17704
71inw
 139 55,5% 180 3.319E-81
2 phalp2_32200
6Xp2c
 36 54,2% 190 3.324E-78
3 phalp2_9688
23BCv
 75 34,6% 297 8.200E-63
4 phalp2_31501
3TJjZ
 324 38,3% 253 3.925E-62
5 phalp2_39902
1gI5J
 24 38,8% 247 1.872E-50
6 phalp2_33955
3uisM
 135 31,7% 293 6.523E-50
7 phalp2_32888
3ixlE
 80 33,9% 274 1.915E-45
8 phalp2_8946
3nZcT
 92 29,6% 277 6.654E-45
9 phalp2_15413
23dr0
 42 31,1% 247 9.085E-45
10 phalp2_10861
4keRO
 48 36,0% 261 1.095E-43

Domains

Domains [InterPro]
NLPC_P60
PG_1
Disordered region
Representative sequence (used for alignment): 3ZDZv (284 AA)
Member sequence: A0A8S5T0H0 (258 AA)
1 284 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF00877, PF01471

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctPyh10
[NCBI] 		2827865 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032711 [NCBI]
CDS location
range 25971 -> 26747
strand +
CDS
ATGGCTTCAAAAACGGTCAGCGCGGCGGAGGTGGTTGCCCTCTTCCGCCGTGCACTGGCGGAAAAATGGGGTTACATCTGGGGCGGCACGGGGCAGGTTCACACGCAGCGTGCGCAGGACAGCGCCACCCGCGCGCAGACGATACGCTATGGGCAGCAGTGGGTCGGGCGGCGCGTTGCGGACTGCTCCGGGCTGTTTTGGTGGGCGTATAAGCAGCTGGGCGGGTATATGTACCACGGCAGCAACACCATGTGGCGCAAGTACGCCGCCGCCAAGGGGACATTGCAGGGCGGCAAGCGCACCGACGGTCAGCCGCTCAAGCCCGGCACGGCGGTGTTCCTCACCAAGGGCAGCGACCGTCACCACGTCGGGCTGTACGTCGGCGATGGTAAGGTCATCGAGGCAAAAGGCACGGCTTATGGTGTGGTCGAGAGCAAAATCACCCGCTGGAACGAGTGGGCGGAGCTGACCGGCACGTCTTACGCCGTGGATGCCCCTGATTCGCCCGCTGACACGCCCGACACACCCGCACCGACCGAGAACCCGGCGGATGCCGGAGACGGCGCAAGCCCCCTTCTCGTCCTCAGGAACGGCAGCAGAGGAACGCAAGTCAAAGTTCTGCAATACCTGCTGATTGACGCAGGATTCGACTGCGGCAAGGTGGACGGCATCGTCGGCAAGAACACCATCGCCGCCGTCAAGGCATTCCAGACCGCGCACAGTTTGACCGCGGACGGCATCGTCGGCGCGAAGACGTGGGCGGCACTGCTCCAATAG

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3ZDZv) rather than this protein.
PDB ID
3ZDZv
Method AlphaFoldv2
Resolution 88.00
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50