Protein

Protein accession
A0A8S5SSE1 [UniProt]
Representative
4yvE1
Source
UniProt (cluster: phalp2_19667)
Protein name
Muramidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MATREQALGFIKEIAPIVQDVCKSRDKWILPSVAIAQAACESNWGTSKAMAAANGLFGFKVGKGIKYGDGWKGKSYSTKTKEFYNGYVTITDNFRAYDSVRDAVVDYMDLLCSLSRYKAAANETNAQKCITAIKNGGYCTSPTYIATIMSIIRTYNLTQYDSAVKLQVSGTLYAAVAGFCNTAAECQAFQKQLQAAGMITQVWEVKPVKNIS
Physico‐chemical
properties
protein length:212 AA
molecular weight:23151,3 Da
isoelectric point:9,08
hydropathy:-0,09
Representative Protein Details
Accession
4yvE1
Protein name
4yvE1
Sequence length
239 AA
Molecular weight
25545,04610 Da
Isoelectric point
4,98082
Sequence
MATKDQVNNFITQLAALACAEYAKREKWVLPSVCIAQAALETGWGTSGLMTKANAYFGIKAGTSWKGKVYSSKTSECYDGVNYTTITDTFRAYDNVEASVADYYDLICGATRYAGAVNNADAESAITAIKNGGYATSPTYVKNVMSIINTYNLTQYDTRDGSNQAAASGTSNQAAESTGEYKVGDVVRVINPVTYNGVKFAVYYSEYDVIQVNGDRVVIGIGTTVTAAVNAANIAKDNE
Other Proteins in cluster: phalp2_19667
Total (incl. this protein): 134 Avg length: 256,6 Avg pI: 7,65
Protein ID Length (AA) pI
4yvE1 239 4,98082
13Beo 253 9,32350
13z77 172 7,61991
1J6LP 223 9,83093
1cTBx 261 9,17026
1f9fy 222 9,67034
1gHl6 239 9,48886
1gIRw 239 9,32156
21GdN 248 9,48235
21fiC 244 8,90387
21q4v 245 8,76907
21wiI 253 9,36985
2VbuC 258 8,87564
2VjIT 248 5,39831
2fWVh 248 9,41756
38HCY 258 8,94236
38NU6 252 9,08858
3KQdh 305 6,74005
3LSNh 264 5,62492
3PAD9 301 9,44006
3TScg 196 9,22815
3bYEz 250 8,58366
3e3cd 264 8,66463
3nIHW 298 9,47403
3pgOW 147 9,39067
3qEpN 296 9,12152
3qOTB 307 4,22299
3rQcK 307 4,30103
3rrjO 214 7,59189
3tElz 305 4,17098
3tYRg 297 5,35818
3ue8U 261 8,48464
3vVgd 265 8,46484
3vrxz 198 4,93876
3wgQr 230 7,59189
3xLBB 303 4,19724
41orY 249 8,37588
4VRR5 286 4,97588
4kfDu 245 8,73606
4y4ZI 334 5,13133
4y5c6 321 4,79604
4y9Sw 265 5,20511
4yqwh 321 4,75000
4z3cS 249 6,32177
5KEFw 274 8,84353
5MkZd 268 8,94707
5NhxI 232 4,94916
5O8LP 269 6,40276
5O9j8 251 9,13757
5Q2xH 230 8,27034
5QVlL 255 8,71008
5Rdw3 314 5,26064
5SnRZ 276 8,71395
5TTbo 322 4,31871
5Txq2 299 8,86816
5TyOw 269 8,78132
5W9nY 249 9,00444
5WHhS 232 4,87942
5WLBP 268 8,64129
5WTeE 308 5,83267
5Wp78 212 9,27644
5X4Kg 247 9,51884
5XRWU 268 8,66424
5XYgd 269 9,03210
5YJsp 184 9,06453
5YuI1 261 8,82039
5nSW 262 9,32440
602bq 230 7,59189
62G1I 323 4,25993
62He5 222 8,74741
63ASM 232 5,02976
63KRB 284 8,76501
64VZH 233 5,02976
67Uqh 233 5,16976
67ZzX 232 5,39120
69Dzn 269 8,63446
69RVX 212 8,80846
69uQa 232 5,12650
6a4a1 213 7,49942
6bR6I 188 4,84594
6bchD 255 8,87344
6cnV7 257 8,67791
6datd 248 9,11533
6djZ4 239 9,63920
6eO8v 266 5,69785
6fcAB 210 5,57490
6fenf 258 8,75437
6gWqW 258 9,25116
6hS5t 232 5,25280
6hjOv 264 8,65851
6hw5d 252 8,89678
6imFz 262 8,91097
6jvv0 309 9,20230
6kUFI 233 9,19617
6l0xO 266 5,71933
6l6Qe 204 8,91754
6lN7B 185 8,26357
6mG0V 268 8,06946
6mLn0 299 9,29797
6mXko 197 8,65696
6mguh 299 4,06123
6mgup 271 5,76327
6mv9E 218 8,76572
6nKyg 252 9,08026
6o8WR 278 8,75934
6rLIC 258 8,90381
6s3vD 185 9,14673
6sX6B 258 8,97898
6tX2c 305 4,12227
6u7jQ 272 8,93282
6vGpA 265 8,96267
6va4X 265 5,07768
6wKjx 345 8,73342
6wNrR 255 8,88382
7P6EY 305 4,10266
7WWv4 252 9,10495
7X0Zy 314 5,13923
7XKFl 258 8,52635
7YYU0 244 9,14176
7ZOuv 254 6,46893
7rUwc 181 8,91155
7sKOx 286 5,06409
7xWOE 230 7,59189
88CkU 259 8,84624
8bynO 286 5,07319
8cylr 358 8,25719
8dgXU 307 9,14428
8kQHy 255 8,66876
8loqX 230 8,26274
8qPHp 265 7,47378
8uIr7 245 8,71440
oJ95 233 8,86455
yn9e 221 6,33194
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_28304
13qfb
 5 51,5% 196 2.810E-70
2 phalp2_21235
1gIfg
 3 50,8% 177 2.874E-61
3 phalp2_2026
2muJS
 52 46,6% 150 8.891E-48
4 phalp2_17322
4k4va
 55 36,9% 249 3.813E-46
5 phalp2_2210
4f9X6
 94 49,6% 149 9.756E-46
6 phalp2_3102
419EZ
 42 44,3% 151 2.437E-42
7 phalp2_19230
41fA9
 30 40,7% 179 2.361E-39
8 phalp2_36044
5XzlK
 69 43,4% 161 4.409E-39
9 phalp2_33491
7wA0y
 13 36,8% 190 4.409E-39
10 phalp2_29953
8uJbN
 74 37,5% 192 2.101E-38

Domains

Domains [InterPro]
GLUCO
Unannotated
Representative sequence (used for alignment): 4yvE1 (239 AA)
Member sequence: A0A8S5SSE1 (212 AA)
1 239 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ct2Qy24
[NCBI] 		2827656 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032666 [NCBI]
CDS location
range 36474 -> 37112
strand -
CDS
ATGGCAACACGAGAACAGGCACTGGGCTTTATCAAAGAGATCGCACCGATTGTGCAGGACGTCTGCAAGAGCCGGGACAAATGGATTTTACCATCCGTGGCGATTGCGCAAGCAGCCTGCGAAAGCAACTGGGGGACAAGTAAAGCTATGGCAGCAGCAAACGGGCTGTTTGGCTTTAAGGTCGGCAAAGGCATAAAGTACGGAGACGGATGGAAAGGCAAGTCCTACAGTACCAAAACCAAAGAGTTTTATAACGGCTATGTCACGATCACGGACAATTTCCGGGCGTATGATTCGGTGCGGGATGCAGTCGTGGACTACATGGACTTGCTGTGTAGCTTGTCCAGATACAAGGCGGCCGCAAACGAGACCAATGCCCAGAAGTGCATTACCGCCATTAAAAACGGCGGATATTGCACCAGTCCGACGTACATTGCTACAATAATGAGTATTATAAGGACGTATAACTTGACGCAATATGACAGCGCTGTGAAGCTGCAGGTATCCGGTACACTTTATGCTGCGGTTGCCGGTTTTTGCAATACAGCGGCGGAGTGCCAGGCATTCCAGAAACAGCTACAGGCTGCGGGAATGATTACGCAGGTCTGGGAGGTAAAACCTGTTAAAAATATTTCGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (4yvE1) rather than this protein.
PDB ID
4yvE1
Method AlphaFoldv2
Resolution 86.57
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50