Protein

Protein accession
A0A8S5SRI4 [UniProt]
Representative
6g1jy
Source
UniProt (cluster: phalp2_19915)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNIVEKTYKWAKPLSKRGTTDLLILHHAAATSCTAEDVHRWHVGNGWAGIGYHYLVRKDGTIYRGRPEDTVGAHAYGANSRSIGVCFEGNYQVERSMPAAQLAAGQALVADIKRRWGITKVIGHKDVAGSTTDCPGKYFPLAEMISGKAETTTNNTTEEDIIMVATQMIGNGDRGNAVRSMQGALIAQGYSCGSYGADGICGAATVAAIKTCQTANGLTADGICGKDTWGALLKK
Physico‐chemical
properties
protein length:235 AA
molecular weight:24941,0 Da
isoelectric point:8,63
hydropathy:-0,23
Representative Protein Details
Accession
6g1jy
Protein name
6g1jy
Sequence length
376 AA
Molecular weight
43019,55750 Da
Isoelectric point
9,65983
Sequence
MNIISKNLTFREVLQKRKSTKYIILHHAAATKCSVEDIHRWHLNNGWAGIGYHFLVRKDGSVYRGRPEDTIGAHTYGSNSISIGICFEGNFENERMTDAQKKAGQQLVYELKKKHPRVQIKKHNDFGRTACPGKYFPFNEIKNYNPNLTNTVNNDKKMTYSYNALTGVRMVKTPIENFKIVYWDARKKTTLHQNYCNAGFFGWGANGSTTPGANLVIDGTIKSQCYTSPSWHNFCKKKVSTFVVTKDNKCSIQVVDRVDNIPNVKYAISGLPVTENYNDVSWANFAKPQGWFGNELSPTKHIFLSFKDGYVYIFGFATKTRNNPYRALTEVWKKLKPYNFKDILMLDGGGSYIMNVNGKAVDYTSENRRINTIIKF
Other Proteins in cluster: phalp2_19915
Total (incl. this protein): 3 Avg length: 302,0 Avg pI: 9,19
Protein ID Length (AA) pI
6g1jy 376 9,65983
A0A8S5P3H1 295 9,26786
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3173
8mQDL
 1 32,7% 369 8.842E-37
2 phalp2_32879
3eTIg
 3 29,7% 373 8.879E-32
3 phalp2_20440
3nOVX
 65 37,4% 259 2.982E-28
4 phalp2_31516
3ZAQL
 7 30,0% 333 1.332E-27
5 phalp2_28578
8ccIC
 2 28,6% 384 6.975E-25

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 6g1jy (376 AA)
Member sequence: A0A8S5SRI4 (235 AA)
1 376 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctIi724
[NCBI] 		2827731 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032658 [NCBI]
CDS location
range 9826 -> 10533
strand +
CDS
ATGAACATCGTAGAAAAAACCTACAAATGGGCAAAGCCGCTCAGCAAGCGCGGCACGACGGATCTGCTGATCCTGCACCACGCGGCGGCCACATCGTGTACGGCGGAGGACGTCCACCGCTGGCACGTCGGCAACGGCTGGGCGGGTATCGGCTACCACTATCTGGTGCGCAAGGACGGCACGATCTATCGCGGTCGACCCGAAGATACCGTGGGCGCGCACGCCTATGGGGCTAACAGCCGCAGCATCGGCGTGTGCTTCGAGGGCAACTATCAGGTGGAGCGGAGTATGCCCGCCGCGCAGCTGGCCGCTGGACAGGCGCTGGTGGCCGATATCAAGCGGCGCTGGGGCATCACCAAGGTGATTGGCCACAAGGACGTTGCCGGATCTACCACGGACTGCCCGGGCAAGTATTTTCCGCTTGCGGAGATGATTTCCGGCAAGGCAGAAACGACCACCAACAACACGACCGAGGAGGACATTATCATGGTAGCAACTCAGATGATCGGAAACGGCGACCGCGGCAACGCGGTGCGCAGTATGCAGGGCGCGCTCATTGCGCAGGGCTATTCGTGCGGTAGCTACGGCGCGGACGGCATCTGCGGCGCGGCGACCGTCGCGGCCATCAAGACTTGTCAGACCGCGAATGGTCTGACGGCGGACGGCATCTGCGGTAAGGATACTTGGGGAGCGCTGCTCAAGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008270 zinc ion binding molecular function None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6g1jy) rather than this protein.
PDB ID
6g1jy
Method AlphaFoldv2
Resolution 93.65
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50