Protein

Protein accession
A0A8S5SJ26 [UniProt]
Representative
5WJa5
Source
UniProt (cluster: phalp2_2526)
Protein name
Peptidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MTPFAGINRITSPYGYREYWYNGRLIKEQHKGQDIVPTQQAGQALPESAWDVREVTGGTVTAVSTGYNGGRGNLVKIQTAPGVVEIYQHLKTITVKVGQTVRQGDMIGVAGSTGQVTGRHLHFEVQVNGAAVEPSAWSDLPNKASTYNGNDTLDHPAEDVDKQYKATVLVDGLRLRPYPEADDFNANNAIATLVKGKVYDLKQTRNGWAFLLTDEGSGGWACIEDSNGKYLDIKEA
Physico‐chemical
properties
protein length:236 AA
molecular weight:25698,3 Da
isoelectric point:5,74
hydropathy:-0,49
Representative Protein Details
Accession
5WJa5
Protein name
5WJa5
Sequence length
236 AA
Molecular weight
25745,33100 Da
Isoelectric point
5,73638
Sequence
MTPFAGINRITSPYGYREYWYNGRLIKEQHKGQDIVPTQQAGQTLPESAWAVREVTGGTVTAVSTGYNGGRGNLVKIQTAPGVVEIYQHLKTITVKVGQTVRQGDVIGVAGSTGQVTGRHLHFEVQVNGTAVEPSAWSDLPNKADTYNGNDTLDHPAEDAYKQYKATVLVDGLRLRPYPEADDFNANDAIATLVKGKVYDLKQTRNGWAFLLTDDGSGGWACIEDSNGKYLDIKEV
Other Proteins in cluster: phalp2_2526
Total (incl. this protein): 10 Avg length: 239,0 Avg pI: 5,86
Protein ID Length (AA) pI
5WJa5 236 5,73638
3kjDV 236 6,52110
6BYa5 240 5,33311
6ikkp 249 5,34681
6p5xS 249 5,48271
7YdP5 236 6,21025
87Icf 236 6,09566
87gQc 236 5,96391
8m2fi 236 6,21304
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_34297
3piy6
 33 29,2% 239 2.894E-22
2 phalp2_9303
7pYyV
 24 36,2% 174 1.160E-20
3 phalp2_5933
67ENK
 29 36,9% 149 1.834E-19
4 phalp2_28378
1lkGC
 5 32,0% 178 2.491E-19
5 phalp2_9448
ugTX
 6 36,2% 171 3.384E-19
6 phalp2_26783
3nNIt
 15 34,3% 189 4.597E-19
7 phalp2_25593
3WFbK
 1 31,2% 163 2.123E-18
8 phalp2_39908
1iVNq
 39 36,7% 147 6.955E-16
9 phalp2_5213
453FH
 7 32,9% 155 1.444E-14
10 phalp2_22360
8MADT
 6 28,6% 223 8.076E-12

Domains

Domains [InterPro]
PET_M23
Unannotated
Representative sequence (used for alignment): 5WJa5 (236 AA)
Member sequence: A0A8S5SJ26 (236 AA)
1 236 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01551

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctFPV4
[NCBI] 		2827819 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032609 [NCBI]
CDS location
range 6803 -> 7513
strand -
CDS
ATGACACCATTTGCAGGAATCAACAGAATCACAAGCCCTTACGGATACCGGGAATACTGGTATAATGGCCGTCTCATCAAGGAGCAGCATAAGGGACAGGACATTGTTCCGACGCAACAGGCCGGACAGGCACTGCCCGAAAGCGCATGGGATGTTCGGGAGGTGACGGGCGGAACGGTAACAGCTGTGAGCACAGGTTATAACGGTGGACGCGGCAATCTGGTAAAGATACAGACAGCGCCGGGCGTGGTCGAAATTTACCAGCACCTGAAAACCATTACTGTGAAAGTCGGTCAGACCGTTCGACAAGGCGATATGATTGGCGTTGCTGGCAGTACGGGGCAGGTTACAGGCCGTCACCTGCATTTTGAGGTTCAGGTAAATGGCGCAGCTGTTGAGCCTTCCGCGTGGAGCGATTTGCCGAATAAGGCGTCTACTTACAATGGCAATGATACGCTTGACCATCCTGCGGAAGATGTGGACAAGCAGTACAAAGCTACAGTGCTTGTTGATGGTTTGAGACTACGCCCGTATCCAGAGGCGGATGACTTCAACGCTAACAATGCCATTGCAACGCTCGTTAAAGGTAAAGTATACGACCTGAAACAGACCCGAAACGGCTGGGCATTCCTCCTTACCGATGAGGGTTCCGGCGGATGGGCGTGCATTGAGGATTCAAACGGTAAATATTTGGATATCAAGGAGGCGTAG

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5WJa5) rather than this protein.
PDB ID
5WJa5
Method AlphaFoldv2
Resolution 83.82
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50