Protein

Protein accession
A0A8S5SHY1 [UniProt]
Representative
K6KP
Source
UniProt (cluster: phalp2_12486)
Protein name
Endolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 85% (predicted by ML model)
Protein sequence
MNPYQRGQKALCGDYFKYTPSGAGQFKRAGRWHAVPQAGDVVFFFSSAMGRIAHVGIVESVEGNKITTIEGNTSGTHGDRNGGECRRKTYSNFSVGGKNWVNGFGRPVYGGDTCIVQELLDIARGEIGYEEKASPNGLEDKHANGGNKNYTKYGQWYNNGKALSEFWCAEFVSWCFYMACKNHTTAQQEPRKEGWIQQQDKWLYYKDSTPVCGKFEYINGRWYVFDNAGFMIKGWFKSDEGWYYLGEDGGMLAGQWLQDKGKWYYLTKSGLMATSAKVKKAKGQGFDYVGPDGAYDPVKSLFTNRMEGVEMVE
Physico‐chemical
properties
protein length:313 AA
molecular weight:35249,1 Da
isoelectric point:8,49
hydropathy:-0,67
Representative Protein Details
Accession
K6KP
Protein name
K6KP
Sequence length
157 AA
Molecular weight
17221,94430 Da
Isoelectric point
9,11417
Sequence
MKGEYMNPYQRGQKALCGDYFKYTPSGAGQFKKAARWHTTPKAGDVVFFFSPAMGRIAHVGIVESVEGNKITTIEGNTSGTHGDRNGGECRRKTYNGFSVGGRNWVNGFARPVYGDDTCTAQELLDVARGEIGYEEKASPQGLEDKHANRGSKNYTK
Other Proteins in cluster: phalp2_12486
Total (incl. this protein): 9 Avg length: 213,4 Avg pI: 8,48
Protein ID Length (AA) pI
K6KP 157 9,11417
41hZB 148 5,75196
6Z6aF 211 8,10982
7Mc9g 193 9,51761
7NJ2P 194 9,50098
NMOE 188 8,94578
OiYT 204 8,84959
A0A8S5VA10 313 8,02317
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_25007
OIvT
 5 56,7% 97 8.166E-46
2 phalp2_4477
3gdle
 1 32,4% 108 1.024E-16
3 phalp2_43
7DRjv
 2 41,0% 100 1.941E-11

Domains

Domains [InterPro]
CHAP
Representative sequence (used for alignment): K6KP (157 AA)
Member sequence: A0A8S5SHY1 (313 AA)
1 157 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. cthH09
[NCBI] 		2827915 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032597 [NCBI]
CDS location
range 19353 -> 20294
strand +
CDS
ATGAATCCATATCAGAGAGGACAAAAGGCATTGTGTGGCGACTATTTTAAGTATACGCCTAGCGGGGCGGGGCAATTTAAACGTGCCGGACGGTGGCATGCTGTTCCGCAAGCCGGAGATGTGGTTTTCTTCTTTAGCTCGGCAATGGGAAGAATCGCCCATGTGGGAATCGTTGAGAGTGTGGAAGGCAACAAGATCACTACCATTGAGGGCAACACTTCCGGCACTCATGGAGATAGAAACGGCGGAGAATGCAGAAGAAAAACTTACAGTAATTTCTCCGTAGGCGGCAAGAACTGGGTAAATGGCTTTGGGAGACCTGTCTATGGAGGCGATACTTGCATAGTACAGGAACTTTTAGACATTGCCCGGGGAGAAATTGGCTATGAGGAGAAGGCGTCCCCCAATGGTTTGGAGGACAAACACGCCAACGGAGGAAATAAGAACTATACGAAATACGGACAATGGTACAACAACGGAAAGGCCTTATCCGAGTTCTGGTGTGCTGAGTTCGTAAGCTGGTGCTTCTACATGGCTTGCAAGAATCATACCACAGCGCAGCAGGAGCCGCGGAAAGAAGGCTGGATTCAGCAACAGGATAAATGGCTGTACTATAAGGATAGCACGCCTGTATGTGGCAAATTTGAGTATATTAACGGCCGCTGGTATGTGTTTGATAATGCAGGATTCATGATTAAGGGCTGGTTTAAGTCTGATGAGGGCTGGTATTACCTTGGAGAGGATGGCGGTATGCTTGCAGGGCAATGGTTGCAGGATAAAGGCAAATGGTACTACTTGACTAAGTCTGGCTTAATGGCAACAAGTGCCAAAGTCAAAAAAGCGAAAGGACAAGGCTTTGACTATGTAGGTCCTGACGGCGCCTATGATCCTGTGAAATCTCTATTTACTAACCGAATGGAAGGAGTTGAGATGGTAGAGTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (K6KP) rather than this protein.
PDB ID
K6KP
Method AlphaFoldv2
Resolution 93.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50