Protein

Protein accession
A0A8S5SGX7 [UniProt]
Representative
1kg2x
Source
UniProt (cluster: phalp2_37124)
Protein name
Phosphodiester glycosidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MQFYRDGSVYVTIVEKREIKRIDFDTCQQPAETLSAYYARQREKPTILTNGGFFNMSTREPVFNYVDEGERKASNTKYKWGMGVVGNNQLIYGELNSRKWRDFVSGYPNLLDDSQAIKITFAKEINYKARRTLLGYDNERVMLVCVDNPGMNLVEAQAYMKKLGCKYAINLDGGGSTGMLVNGEKKTSTAYNRAVDNVVAIYTKDTAPKKPTTTTSTNRTSQGFLIPDKTLNLYTPSGRGFTVYQKIVPDFFRAPKDIASYVKKGQPIKPCALVNNGTGFPRGITVHNTSTLAAASGTTPAEVYCRATYNGNMGGAMVHYYVDKYSIWQLLCTSEARTERGWHAGDGSSRRTAHDKATKGVIIGGNLDTIAIEVIGSYKEAEDNAAKLIAFLCDIHDLTINDIYTHNWFMGQPDDKIIYGARKNCPVYIIPHWAEFLDKVASYAGWRTGNNSPSTTTTKYSVGDKYTIKSGDVYTNGKAVPPSIVGRVFTVSKINTSGTAILLKEINSWVKI
Physico‐chemical
properties
protein length:512 AA
molecular weight:56878,9 Da
isoelectric point:9,23
hydropathy:-0,40
Representative Protein Details
Accession
1kg2x
Protein name
1kg2x
Sequence length
502 AA
Molecular weight
55683,46970 Da
Isoelectric point
8,79789
Sequence
VTIVPKWEIKRIDFDACQQPAETLSAYYARQSEKPTILTNGGFFNMSTREPVFNYMDEGKAKATNAKYKWGMGIIGENQLIYGELNSRRWRDFVSGYPNLLDDSQSITITFAKEINYKARRTLLGYDDDFVMLVCVDNPGMNLIEAQAYMKKLGCKYAINLDGGGSTGMFVNGEKKTSSAYNRAVDNVVAIYTKGTAPTKPTTTASTDRTSQGFLIPDKTLNLYTPSGRGFTVYQKIVPNTFRAPKDVASYVKKGQPIKPCALVNNGTGYPRGITVHNTSTLDAPSGTTPAEVYCRATYNGNMGGAMVHYYVDEYSIWQLLCTSEGHVERGWHAGDGSTRRTAHDKATKGMIIGGNLDTIAIEVAGNYKEAEDNAAKLIAFLCDIHDLTINDIYTHNWFMGQPDDKIIYGARKNCPVYIIPHWTEFLNKVVSYSEWKMGNNSPSTTMSKYSVGDKYTIKSNDVYTNGKTVPASMVGRAYTVSKVNNTGTAILLKEINSWVKI
Other Proteins in cluster: phalp2_37124
Total (incl. this protein): 6 Avg length: 546,8 Avg pI: 9,11
Protein ID Length (AA) pI
1kg2x 502 8,79789
3a1Jl 609 9,19501
5Nd9R 551 9,31660
6bSHm 551 9,21281
6uUtd 556 8,90819
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_39583
6lzER
 145 23,0% 443 4.048E-30

Domains

Domains [InterPro]
NAGPA
Ami2
Unannotated
Representative sequence (used for alignment): 1kg2x (502 AA)
Member sequence: A0A8S5SGX7 (512 AA)
1 502 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510, PF09992

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctBCr48
[NCBI] 		2827802 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032595 [NCBI]
CDS location
range 101891 -> 103429
strand -
CDS
ATGCAATTCTATCGAGACGGTAGCGTCTATGTGACAATTGTTGAAAAGCGTGAAATCAAGCGGATTGATTTTGATACTTGTCAACAGCCAGCAGAGACGTTATCAGCCTACTATGCGCGACAAAGGGAGAAGCCCACAATTCTTACCAACGGTGGATTCTTTAATATGTCGACACGTGAGCCTGTGTTCAACTATGTTGACGAAGGCGAACGTAAAGCGTCCAACACTAAGTATAAGTGGGGAATGGGCGTTGTTGGAAACAATCAGTTAATCTATGGCGAATTAAACAGTCGTAAATGGCGTGATTTTGTATCTGGCTATCCTAATTTACTTGATGATTCACAAGCGATTAAGATAACCTTTGCCAAAGAAATTAACTATAAAGCAAGGCGAACGCTTCTTGGGTATGACAACGAGCGAGTAATGCTCGTATGTGTCGATAATCCCGGAATGAATCTTGTAGAAGCACAGGCTTATATGAAGAAGCTCGGTTGCAAGTACGCAATCAATCTTGATGGTGGAGGGTCTACAGGAATGCTTGTTAATGGTGAAAAGAAAACATCTACAGCATATAATCGTGCGGTTGATAATGTTGTTGCTATTTATACTAAGGACACAGCCCCCAAAAAGCCCACAACGACCACTAGCACAAACAGAACAAGTCAAGGTTTCCTTATTCCTGATAAGACCTTGAATCTTTATACGCCAAGCGGTAGAGGATTCACGGTTTATCAAAAGATTGTCCCTGATTTCTTTCGTGCGCCCAAGGATATTGCTTCATATGTCAAGAAGGGTCAGCCCATCAAGCCATGCGCATTGGTCAATAATGGCACAGGATTTCCGAGGGGCATAACAGTTCACAACACATCGACTCTTGCGGCGGCAAGTGGCACTACTCCTGCTGAGGTTTATTGTAGAGCGACCTATAACGGCAATATGGGCGGTGCAATGGTTCACTACTACGTTGACAAGTATTCAATCTGGCAACTGCTTTGTACCTCTGAGGCTCGTACTGAACGTGGCTGGCACGCCGGAGACGGTTCATCAAGGCGCACAGCACATGATAAAGCGACCAAGGGTGTGATCATAGGGGGCAACCTTGATACCATCGCTATAGAGGTTATAGGCAGCTACAAGGAAGCCGAAGACAATGCTGCAAAGTTGATTGCTTTCCTTTGTGATATTCACGACTTGACAATCAACGACATCTACACGCATAACTGGTTCATGGGTCAGCCGGATGATAAAATAATCTATGGCGCAAGAAAGAATTGTCCTGTCTATATTATCCCCCATTGGGCAGAATTCTTAGACAAGGTAGCATCTTACGCAGGATGGAGGACGGGTAATAATTCCCCATCAACAACCACCACCAAATATTCCGTAGGTGATAAATACACCATCAAATCGGGTGACGTATATACCAACGGCAAAGCAGTTCCGCCATCAATAGTAGGTCGTGTGTTCACTGTATCCAAAATCAATACAAGTGGAACGGCGATTCTATTAAAAGAAATAAATTCATGGGTTAAGATTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0016798 hydrolase activity, acting on glycosyl bonds molecular function None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1kg2x) rather than this protein.
PDB ID
1kg2x
Method AlphaFoldv2
Resolution 87.92
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50