Protein

Protein accession
A0A8S5S6V1 [UniProt]
Representative
5UAVR
Source
UniProt (cluster: phalp2_39561)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MIKIMLDPGHGAGRNFNRGSVIGNEGDNNYKYSLVLKRELEKYGFYVGTTRNSITDNPSLSARGNKAKGYDLFISLHSNAANSSVRGIEIYGDINANSPQLMKNLCNNISKVIGTKNRGVRWRTRNPERFYVQPTSPGGSNYYGVLYSNKAKLGMLIEHVFHTNREDCKLYVEKRKEIAQATADTIAQFYGLKKINRPQTKAEVKGVSKLELTKEQKDSVKNTVVTYLDEEYQKAYIIAQEHKALLAPAPFNFDFGRMVKSGDTIIAVGGDHLGKIEGKNYGLTNYATYHVKATDKAEDFNKDRSKFLVRK
Physico‐chemical
properties
protein length:311 AA
molecular weight:34968,3 Da
isoelectric point:9,60
hydropathy:-0,64
Representative Protein Details
Accession
5UAVR
Protein name
5UAVR
Sequence length
314 AA
Molecular weight
35259,53680 Da
Isoelectric point
9,42516
Sequence
VEQDMTIKIMLDAGHGAGRDFNRGSVIGNEGDNNYKYSLVLKRELEKYGFYVGTTRNSITDNPSLSQRGNKAQGYDLFISLHSNAANSSVRGIEIYGDINANSPVLMKNLCANISRAIGTKNRGVRWRTRNPERFYVQPISPGGSNYYGVLYSNKAKLGMLIEHVFHTNREDCKLYVEKRKEIAQATADTIAQFYGLKKITRPKVEVKGVSKLELTKEQKDSVKNTVVTYLDDEYQKAYIIAQEHKALLAPAPFNYDFGRMVKSGDTIIAVGGDHLGKIEGKNYGLTGYATYHVKATDKAEDFNKDRSKYLVRK
Other Proteins in cluster: phalp2_39561
Total (incl. this protein): 13 Avg length: 309,4 Avg pI: 9,53
Protein ID Length (AA) pI
5UAVR 314 9,42516
5Kx3S 310 9,60413
5LtQU 311 9,51877
5Vnqb 308 9,55101
68Kwz 309 9,57383
6iRpR 314 9,33929
6lbYU 291 9,68059
6skEb 309 9,47010
6uCf6 311 9,47319
7BTeg 310 9,63984
8eySD 312 9,50781
wyKO 312 9,50768
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_22085
5PV79
 1 50,6% 225 3.869E-63
2 phalp2_9278
79Kdt
 5 42,2% 194 2.014E-36
3 phalp2_39497
5jS1N
 14 41,9% 217 1.864E-26
4 phalp2_19894
5T9s7
 90 38,4% 203 1.755E-24
5 phalp2_20787
5Hy1d
 27 39,6% 202 1.328E-21
6 phalp2_40616
7KnbL
 4 31,4% 232 2.505E-17
7 phalp2_24413
4m1OU
 1246 30,8% 211 1.756E-12
8 phalp2_27800
7z5TK
 19 29,8% 275 4.262E-11
9 phalp2_23918
1NTlO
 42 30,3% 211 1.806E-10
10 phalp2_29815
2324Y
 17 27,6% 195 3.214E-10

Domains

Domains [InterPro]
Ami3
Unannotated
Representative sequence (used for alignment): 5UAVR (314 AA)
Member sequence: A0A8S5S6V1 (311 AA)
1 314 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ct1ba2
[NCBI] 		2827654 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK032540 [NCBI]
CDS location
range 18333 -> 19268
strand +
CDS
ATGATTAAAATAATGTTAGATCCAGGTCACGGAGCAGGACGCAATTTTAACCGTGGCTCAGTTATTGGAAACGAAGGCGACAATAACTATAAATACTCACTCGTTTTAAAGCGTGAGCTAGAAAAATACGGATTTTATGTAGGTACTACAAGAAATAGTATTACTGATAATCCGTCCTTGTCAGCACGTGGAAACAAAGCAAAAGGATATGATTTGTTCATATCCTTGCACTCAAACGCGGCGAATAGTAGTGTAAGAGGTATTGAGATTTACGGAGATATCAATGCAAATAGTCCTCAACTGATGAAAAATTTATGTAACAATATTTCAAAGGTTATCGGAACAAAAAATCGTGGTGTTAGATGGAGAACAAGGAATCCCGAACGCTTTTATGTACAGCCGACATCACCGGGTGGCAGTAACTACTATGGTGTATTGTATTCAAATAAAGCAAAGTTGGGAATGTTAATAGAACACGTATTCCACACAAATAGAGAAGACTGTAAGTTGTATGTAGAAAAACGAAAAGAGATTGCACAGGCAACGGCAGACACGATAGCACAATTCTACGGACTTAAAAAGATAAACAGACCTCAAACAAAAGCAGAAGTGAAAGGAGTATCAAAGTTGGAACTAACTAAAGAACAAAAGGACAGCGTAAAAAATACAGTTGTGACTTATTTAGATGAAGAATACCAAAAAGCATATATTATAGCTCAAGAACACAAAGCTCTACTTGCACCAGCACCATTTAATTTTGATTTTGGTAGAATGGTTAAGAGTGGTGACACGATTATTGCTGTTGGTGGAGACCATCTAGGCAAGATTGAGGGCAAGAACTACGGCTTAACAAATTATGCAACATATCACGTAAAGGCGACTGATAAGGCAGAAGATTTCAATAAGGATAGAAGTAAGTTTTTGGTGAGGAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5UAVR) rather than this protein.
PDB ID
5UAVR
Method AlphaFoldv2
Resolution 80.49
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50