Protein

Protein accession
A0A8S5RMA6 [UniProt]
Representative
3sm29
Source
UniProt (cluster: phalp2_32904)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSNSTLVDYTKISPNRTSPRNHAIDTITIHCVVGQCSVETLGNIFAPTSRQASSNYGVGVDGRIGMYVEEKDRSWCSSNAANDNRAITIEVASDTAHPYAVNAKAYAALLDLVTDICRRNGIKKLVWSTNKNERVNHLNGCNMTVHRDYANKSCPGDYLYERHGAIAAEVNKRLGASPAEPETPSSGAGTLYKVQTGAFKQKSNAQALEKKLKAAGFDTYVANTGGYYKVQVGAFSKKANADAMLAKLKAAGYSDAFITTGSGGTAAASVKVGSKVRLKQGAKTYDGKSLASFVYNRDHVVKEISGDRAVITYGGVVVAAVKLSDLTLV
Physico‐chemical
properties
protein length:329 AA
molecular weight:35077,2 Da
isoelectric point:9,36
hydropathy:-0,29
Representative Protein Details
Accession
3sm29
Protein name
3sm29
Sequence length
432 AA
Molecular weight
N/A Da
Isoelectric point
9,15665
Sequence
MFNSIVENLVSIGWSMLIFLSAYLANVTFSLWYNIKLLHEPFDREKLINSAYKIATFVIGLTLLCVALTTLPLFANEVGWAIPQEYTDLFADLVIIGAVLLVSCKYIKEAFVKFTEILNAGTSDAQGKXXXXTMSNSPLVDYTRISPNKNSPRNHKIDTITIHCVVGQCTVETLGNIFAPTSRQASSNYGVGTDGKIGMYVEEKDRSWCSSNAANDNRAVTIEVASDTKHPYAVNDRAFAALLDLVTDICKRNGIKKLVWSTKKADRVNHKNGCNMTVHRDYANKSCPGDYLYNRHGEIAAEVNRRLGVADTAPDAGAAQGVTVYTVKKGDTLSQIAAKYGTTYQAIAAYNGIKNPNAIRVGQKIKIPASTAPAALKKGDRVKVLNAVTYDGKPFRTYYDTYDVIQVSGARVVIGVGATVTAAVNAANLRKV
Other Proteins in cluster: phalp2_32904
Total (incl. this protein): 6 Avg length: 359,5 Avg pI: 8,79
Protein ID Length (AA) pI
3sm29 432 9,15665
A0A8S5QL56 454 6,67042
H7BW58 334 9,21526
D6QWN4 302 8,80962
H7BWC9 306 9,54836
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1650
8m87G
 265 48,5% 284 1.179E-78
2 phalp2_15597
2fZru
 53 41,0% 341 6.846E-70
3 phalp2_27209
3o7E3
 7 37,9% 343 7.137E-68
4 phalp2_453
84Dz
 2 27,0% 310 8.685E-25

Domains

Domains [InterPro]
Unannotated
Ami2
LysM
Unannotated
Representative sequence (used for alignment): 3sm29 (432 AA)
Member sequence: A0A8S5RMA6 (329 AA)
1 432 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01476, PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage virus sp. ctvdG25
[NCBI] 		2825827 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK059119 [NCBI]
CDS location
range 3411 -> 4400
strand -
CDS
ATGAGTAACAGCACGTTGGTGGACTACACGAAAATTTCACCGAACAGAACAAGCCCGCGAAATCACGCGATCGACACGATCACAATTCATTGCGTTGTCGGGCAATGTTCCGTTGAAACGCTGGGAAACATCTTTGCGCCGACTTCGCGACAGGCAAGTTCTAATTACGGCGTGGGCGTTGACGGACGTATCGGAATGTATGTCGAAGAAAAGGATCGTTCGTGGTGCAGTTCAAACGCGGCGAACGATAACCGCGCAATCACAATCGAAGTTGCAAGCGACACGGCACACCCTTACGCCGTGAACGCGAAAGCATACGCCGCCCTTCTTGACCTTGTAACGGATATTTGCCGCAGGAACGGGATCAAGAAACTTGTTTGGTCTACGAATAAGAATGAGCGCGTTAATCATTTGAACGGTTGCAATATGACGGTTCATAGAGATTACGCGAATAAATCCTGTCCGGGGGATTATCTGTACGAAAGGCACGGCGCGATCGCGGCGGAGGTAAACAAAAGGCTGGGGGCTTCCCCGGCGGAGCCGGAAACGCCTTCTTCCGGAGCTGGTACGCTTTACAAAGTGCAGACAGGCGCTTTCAAGCAGAAATCGAACGCACAGGCGCTGGAAAAGAAATTGAAGGCGGCTGGTTTCGATACCTACGTCGCGAATACGGGCGGCTATTACAAAGTACAGGTGGGTGCGTTCAGCAAGAAGGCAAACGCCGACGCTATGCTTGCAAAGCTGAAAGCGGCGGGATATTCTGACGCTTTTATTACGACCGGAAGCGGCGGCACGGCGGCGGCTTCCGTGAAGGTGGGAAGCAAAGTACGCTTGAAGCAGGGCGCGAAAACCTACGACGGGAAAAGCCTTGCTTCCTTCGTGTATAACCGCGATCACGTCGTAAAGGAAATCAGCGGAGATCGCGCCGTGATTACATACGGTGGCGTGGTTGTCGCGGCGGTGAAGCTGTCCGATCTGACGCTTGTTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)
GO:0042834 peptidoglycan binding molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

PDB ID
upi000a5730e8_model
Method AlphaFold3 (non-commercial)
Resolution -
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50
The structures below correspond to the cluster representative (3sm29) rather than this protein.
PDB ID
3sm29
Method AlphaFoldv2
Resolution 84.63
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50