Protein

Protein accession
A0A8S5RE65 [UniProt]
Representative
3yVzG
Source
UniProt (cluster: phalp2_8961)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MVINVHGGHNRIVPGASGYLDEVTEDRAVTAQVIAKLRALGHTVYDCTDDSGRTQGQNLANIVHACNAHAADLDVSIHLNSGGGTGTEVLVYSDTGEAAGYAVKICAAISELGYRNRGVKERKALYVLRRTTAPALLVECCFVDSAADAQRFDADKMAAAIVRGITGQTAAQTGAAPAQQTGYHVRITASVLNVRRDHSASSAVATQVRRGEVYTIVAEYNNGGTMWGKLKSGAGWIALKYTQCV
Physico‐chemical
properties
protein length:245 AA
molecular weight:25877,8 Da
isoelectric point:8,20
hydropathy:-0,08
Representative Protein Details
Accession
3yVzG
Protein name
3yVzG
Sequence length
168 AA
Molecular weight
N/A Da
Isoelectric point
8,42990
Sequence
MEINTHGGHNSHVTGASKYLNELKEDRKVKNEVIRLFKANGHTVYDCTDDSGKTQNQNLANIIKKCNDHNVDLDLSIHLNSGGGTGVECWIYPGSSSKDEAECICRNVSKALGIKNRGVKTSSSLYVLKHTKAPAIIIECCFVDSKDDAEKWNAXXXXNVRKLLWKGF
Other Proteins in cluster: phalp2_8961
Total (incl. this protein): 53 Avg length: 182,5 Avg pI: 8,45
Protein ID Length (AA) pI
3yVzG 168 8,42990
1FW3N 146 8,88769
1HvID 166 8,59726
1agyi 218 6,31017
1k7Uz 169 9,35992
21kWv 167 8,90407
24K6z 165 8,62421
2l5pB 206 9,31254
2pl9B 166 8,64626
3AhPm 143 5,35727
3PNJZ 213 9,17709
3PXEH 167 9,45514
3PxAf 173 9,45495
3ZN9o 142 7,96876
3dQyr 166 9,15801
3gTBO 163 9,05976
3gUAU 166 9,01547
3iyFQ 166 9,30074
3nFNV 170 6,07651
3nIju 166 9,06543
3nUB4 167 8,87016
3nxXQ 173 9,62708
3vh0A 168 8,98730
3wmzx 232 5,47294
40XYf 170 8,63485
40c7y 166 8,53653
45rj1 166 8,29020
4LbkC 130 7,01248
4SBEV 241 8,96538
4SObZ 237 8,61048
4hSf3 208 9,42607
4km8o 166 9,20178
4ksug 204 9,39216
5NL8J 166 9,11198
5OFzR 173 9,34310
5Po6U 165 8,96950
5i0Gm 223 5,07660
68KW 181 9,34851
6aZSb 172 8,83180
6pCI9 170 9,30100
6ui8c 170 8,28240
7DTx5 166 7,79160
7bkQl 220 9,00071
7dGPu 220 9,20571
7ed63 226 9,58195
7gTpW 220 9,19637
7ju3m 159 5,27048
7unet 151 6,18007
7unfB 151 6,18013
82zFe 218 9,26348
85Ypl 221 9,33143
8ongD 221 9,34207
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_36719
6eCmw
 993 56,5% 168 1.418E-69
2 phalp2_6374
7yZe6
 41 48,2% 168 7.291E-53
3 phalp2_19930
6wdij
 24 43,1% 167 3.294E-48
4 phalp2_15683
35AAr
 164 34,8% 175 7.893E-44
5 phalp2_19905
69yEp
 107 34,0% 179 1.082E-43
6 phalp2_23331
5tGuH
 43 39,1% 171 7.162E-43
7 phalp2_19262
8ev89
 7 32,9% 176 2.579E-39
8 phalp2_2704
7cWsF
 33 37,2% 169 3.534E-39
9 phalp2_34447
4ANo2
 39 31,4% 175 1.420E-33
10 phalp2_13106
8n51f
 2 32,9% 170 4.516E-32

Domains

Domains [InterPro]
Ami3
Representative sequence (used for alignment): 3yVzG (168 AA)
Member sequence: A0A8S5RE65 (245 AA)
1 168 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520

Taxonomy

  Name Taxonomy ID Lineage
Phage virus sp. ctJLD79
[NCBI] 		2827987 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK059097 [NCBI]
CDS location
range 13130 -> 13867
strand -
CDS
ATGGTTATCAACGTACATGGCGGTCACAACCGCATTGTCCCCGGTGCGTCCGGGTATCTGGATGAGGTGACCGAGGACAGAGCCGTCACCGCGCAGGTCATCGCCAAGCTCCGGGCGCTGGGGCACACTGTCTACGACTGCACCGACGACTCCGGCCGCACGCAGGGTCAGAACCTGGCCAACATCGTCCACGCATGCAATGCTCATGCGGCTGATCTGGATGTGAGCATCCACCTGAATTCCGGCGGCGGCACCGGAACCGAGGTGCTGGTGTACTCCGACACCGGTGAGGCGGCGGGCTATGCCGTCAAAATCTGCGCCGCCATCTCCGAGCTTGGCTATCGCAACCGCGGCGTGAAGGAGCGCAAGGCCCTCTATGTGCTTCGTCGCACCACCGCCCCCGCGCTGCTGGTGGAGTGCTGCTTTGTGGACTCCGCTGCGGATGCGCAGCGCTTTGACGCCGACAAAATGGCCGCCGCCATTGTGCGGGGCATCACCGGCCAGACCGCGGCCCAGACGGGCGCTGCGCCCGCCCAGCAGACCGGCTATCATGTCCGCATCACCGCGTCTGTCCTCAACGTGCGCCGCGACCACAGCGCTTCCAGCGCCGTCGCCACGCAGGTGCGCAGGGGTGAGGTCTACACCATCGTGGCCGAGTATAACAACGGCGGCACCATGTGGGGCAAGCTCAAGTCCGGCGCGGGCTGGATCGCGCTGAAATATACCCAGTGTGTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3yVzG) rather than this protein.
PDB ID
3yVzG
Method AlphaFoldv2
Resolution 93.43
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50