Protein

Protein accession
A0A8S5RBL1 [UniProt]
Representative
NDSw
Source
UniProt (cluster: phalp2_37043)
Protein name
Endodeoxyribonuclease I
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MREIKFLAVHCTATPQTTSVESIQQYWKTQLGWKMPGYHFIIKPNGEVIKLLSVDKVSNGVKGFNSVSINIAYIGGVDSQNNPIDNRTPAQKKALRDLLEKFKIVHPKAIIQGHRDFPNVKKACPSFDAKKEYANI
Physico‐chemical
properties
protein length:136 AA
molecular weight:15309,6 Da
isoelectric point:9,67
hydropathy:-0,39
Representative Protein Details
Accession
NDSw
Protein name
NDSw
Sequence length
86 AA
Molecular weight
9662,95170 Da
Isoelectric point
9,16781
Sequence
MREIKYIAVHCTATPQTATVSSIQNYWKNVLKWKMPGYHFIIKPNGEVVQLLEIEKVSNGVKGFNSVSINISYIGGADSTHRHTDT
Other Proteins in cluster: phalp2_37043
Total (incl. this protein): 22 Avg length: 91,5 Avg pI: 9,05
Protein ID Length (AA) pI
NDSw 86 9,16781
11whm 77 7,92041
1Jmia 91 9,44335
2KKzs 90 9,80005
3dONB 64 8,06662
56fbd 86 8,56651
5MZtL 107 7,11217
5bMgA 90 9,41092
6ZZf4 109 9,58833
70nMO 92 8,78906
7NdEW 85 9,37385
7QGFz 96 9,51768
7VrBX 68 9,89424
7sDwG 136 9,67092
7sDxp 98 9,37385
8tPfl 63 9,57918
DF6R 86 9,30119
JnSU 65 9,51916
jvTA 102 8,62131
oPiu 91 9,51813
xVlm 94 7,11143
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_40545
4KkLG
 4 41,3% 92 3.837E-24
2 phalp2_37273
7XRQ8
 6 48,2% 58 6.054E-18
3 phalp2_21606
2vySa
 303 34,8% 86 1.142E-17
4 phalp2_27898
ipdG
 164 35,7% 70 2.516E-15
5 phalp2_27860
8AZLJ
 3 36,3% 77 3.455E-15
6 phalp2_10521
87KcW
 27 32,7% 61 1.227E-10
7 phalp2_26108
2kvR
 27 33,7% 74 1.134E-09
8 phalp2_32271
7BWDU
 12 25,7% 101 2.940E-09
9 phalp2_9904
2GCXD
 1 35,8% 67 4.039E-09
10 phalp2_39718
8z0Eo
 35 29,8% 57 7.624E-09

Domains

Domains [InterPro]
Ami2
Representative sequence (used for alignment): NDSw (86 AA)
Member sequence: A0A8S5RBL1 (136 AA)
1 86 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage virus sp. ctOZh10
[NCBI] 		2828250 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK059088 [NCBI]
CDS location
range 1924 -> 2334
strand +
CDS
ATGAGAGAAATAAAGTTTTTAGCCGTGCATTGTACGGCAACGCCCCAGACGACATCTGTAGAGAGTATTCAGCAGTATTGGAAAACTCAGTTAGGCTGGAAAATGCCCGGCTATCACTTTATCATCAAGCCCAATGGCGAGGTAATCAAGCTTCTGAGTGTAGATAAAGTTTCTAACGGAGTCAAAGGTTTTAATTCGGTAAGTATCAATATTGCCTACATCGGAGGTGTAGACAGCCAGAACAACCCCATAGATAACCGGACACCTGCCCAGAAAAAGGCTCTTCGGGATTTATTAGAGAAATTTAAAATAGTCCATCCAAAGGCAATAATCCAAGGACACAGGGATTTTCCTAATGTGAAAAAAGCGTGTCCATCATTTGACGCAAAAAAAGAATATGCAAACATCTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (NDSw) rather than this protein.
PDB ID
NDSw
Method AlphaFoldv2
Resolution 96.67
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50