Protein

Protein accession
A0A8S5R2Q3 [UniProt]
Representative
3vaLE
Source
UniProt (cluster: phalp2_38935)
Protein name
Lysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MPKLYVICGHGAGDPGASGNGFDEAERVRALAAAMKKHAGDQFVLCDTTRNYYVDMGILGNSIPSDATILELHMDCADIETAKGGHILTKSGFDINDYDKALAEFISSFFPGRADSVQYVGWLANANRAAAVGKDYRLIECGFISNYDDVKKFNEHIDELACGLLKCFGIECDICNHDKAPVPDPNPTPSTGGDGGVSGAFESGSYVCTVDYLNVRTAPSVSSPSVAHYEKNDEVILDGWYTIADGYVWGRYIGAASGQYRYVAVGKPTGKPEGDDYLIKY
Physico‐chemical
properties
protein length:281 AA
molecular weight:30276,5 Da
isoelectric point:4,77
hydropathy:-0,23
Representative Protein Details
Accession
3vaLE
Protein name
3vaLE
Sequence length
577 AA
Molecular weight
63978,41100 Da
Isoelectric point
4,70993
Sequence
MSNKLFIITGHGAGDPGACGNGYQEYERVRTLAKRCKALGGDNVMVSEENRNYYKDNGITNLTLSKDWLLCEFHMDSSTSSSARGAHVIIWGNYKADAYDEKLAAFLSGILPGRSSTIVGRTNLANPKRAANKGYNYRLIEIGFISNATDVSIFNSKMDEIAKGILECFGVELVQNVVVQQPTNQNSQLYRVRKTWEDAKSQLGAYANLENAKKKCDENEGYSVFDASGKVVYTKATTSTTTDIIYRIRKTWADAGSQKGAYRNLESAKNICDQNPGYSVFDEDGNAVYTSKVETTTPPATEEPKVEEPKEEVIQKPEAPEAVDISPLKGFTKEQFIEYVGSLAKTDMANTGILASVTIAQAILESAWGQSELSLKANNLFGMKSTLSGNTWQSAWTGEIYAKWSNEEVNGQMVPYYSDFRAYATVAESIADHSAYLCGAKKGSVYRYEGLIGETDYTKAIQLIKDGGYATDSAYVSKVVNIIETYKLYEFDIDDKDEESENQEFTENDKVEETPEMDPVVDNENDVVENEPSDEEEENIPEPTPEEPDDEKANLIAKFIINIFKALVKILAGLFKK
Other Proteins in cluster: phalp2_38935
Total (incl. this protein): 17 Avg length: 512,5 Avg pI: 7,65
Protein ID Length (AA) pI
3vaLE 577 4,70993
1dm2C 576 8,06688
3lCRv 543 8,94159
3qOnC 505 9,04977
3qPrJ 501 5,95624
3qhYr 505 9,16620
3sNTu 501 6,35917
5YKwK 512 9,12029
60rHi 512 9,16110
64ooo 512 9,08658
6dnd3 502 9,00470
6lH1i 502 9,17129
6phYE 512 9,17110
7vFmo 582 5,66227
8rKjf 501 7,07193
m0An 589 5,59679
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_3502
4kbYu
 91 36,5% 389 1.599E-83
2 phalp2_20819
6dUOP
 6 21,7% 516 5.737E-39

Domains

Domains [InterPro]
Ami3
Unannotated
Unannotated
GLUCO
Disordered region
Representative sequence (used for alignment): 3vaLE (577 AA)
Member sequence: A0A8S5R2Q3 (281 AA)
1 577 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01520, PF01832

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ctWWc42
[NCBI] 		2826361 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015795 [NCBI]
CDS location
range 25367 -> 26212
strand -
CDS
ATGCCTAAGTTATACGTTATTTGTGGTCACGGTGCCGGCGATCCCGGTGCTAGCGGAAATGGTTTTGACGAGGCAGAACGAGTTCGTGCTCTTGCAGCAGCAATGAAGAAGCACGCCGGCGATCAATTCGTGCTTTGTGACACTACTCGAAATTACTATGTGGATATGGGCATTCTTGGCAATTCGATTCCGTCGGATGCAACTATTCTTGAGCTTCACATGGACTGTGCCGATATCGAAACCGCTAAGGGCGGTCATATTTTAACGAAGTCTGGCTTCGATATTAATGACTATGACAAGGCGCTCGCCGAATTTATTTCCTCTTTCTTCCCTGGTCGAGCGGATTCTGTTCAGTATGTTGGCTGGCTTGCTAATGCTAACCGAGCAGCTGCTGTCGGCAAGGACTATCGTCTTATCGAGTGCGGCTTTATTTCGAACTATGACGATGTAAAGAAGTTTAACGAGCATATTGACGAACTTGCTTGCGGGCTTCTTAAGTGCTTTGGCATTGAGTGCGATATTTGCAATCATGATAAGGCTCCTGTCCCAGATCCTAATCCGACTCCTTCTACTGGTGGTGATGGTGGCGTGTCTGGTGCATTCGAAAGCGGCTCTTATGTTTGTACTGTCGATTATCTGAACGTTCGTACTGCTCCTTCTGTGTCTTCGCCTAGTGTCGCCCATTATGAGAAGAACGACGAGGTTATTCTCGATGGGTGGTACACCATTGCGGATGGCTATGTATGGGGTCGTTATATCGGAGCTGCGTCTGGTCAGTATCGATATGTTGCTGTTGGTAAGCCTACCGGTAAGCCAGAGGGCGACGATTATCTGATTAAGTACTAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0071555 cell wall organization biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3vaLE) rather than this protein.
PDB ID
3vaLE
Method AlphaFoldv2
Resolution 79.64
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50