Protein

Protein accession
A0A8S5R1G2 [UniProt]
Representative
3o2Gm
Source
UniProt (cluster: phalp2_34777)
Protein name
N-acetylmuramoyl-L-alanine amidase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MSQSKLVNYIKLSPHCTKPRQGRIKGISIHTMAGPGSVEGCGQVFQQREASSHYGIGPDGRIGQYVLEENRAWCTSHKVDHEVVTIEVSSIQSYKEPYECTKKAYVALINLCVDICKRNGIKKLIWKEGKQYCPAFTGNWAVCNMVPHRYTRPDKSCPGNYLFSKYGEIAAEVNKRLQATTKPVEEVEEDMDINTFIKEMTPEQAYTLLQKASQYVASKPEPDWSKQEGHWNKATQQKLVNGEAPEGFLKRDEFIAVMGRKGLI
Physico‐chemical
properties
protein length:264 AA
molecular weight:29850,8 Da
isoelectric point:8,73
hydropathy:-0,59
Representative Protein Details
Accession
3o2Gm
Protein name
3o2Gm
Sequence length
272 AA
Molecular weight
30525,11980 Da
Isoelectric point
5,07842
Sequence
MSNSPMVDFVLISPHKNSPRNNKILKITIHHMAGNLSVEACGRLFQTRQASSNYGIDNEGRVGMYVEEKDRSWCSASPWNDNQAITIEVANDGGAPDWHVSDKALATLIDLCVDICERNGIERLVYTGDTDGNLTRHNMFCATACPGPYLQSKFPWIAEQVNKRLSEGGKMVKLKIGYASSGDMRTFRNLLISLGVTFSEEGGYITTDYVTSYQRSVIEDKADLLIVPCVVIDEKPEEPDEYKEKYEAVLEEYNNFKGYVRNIYDELGGLLK
Other Proteins in cluster: phalp2_34777
Total (incl. this protein): 14 Avg length: 274,5 Avg pI: 7,09
Protein ID Length (AA) pI
3o2Gm 272 5,07842
21L4l 272 5,26832
23HIX 255 6,32291
3TKdm 255 8,41701
3VJz1 288 8,78886
3ZOjS 286 8,41211
3ZSBT 255 6,60295
3bGH5 294 8,53557
40fgb 305 5,04642
41qD1 255 8,41108
4kfqv 312 8,45472
4kp00 289 5,14253
7G6CC 241 6,05298
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_33971
40cAJ
 14 58,0% 181 2.509E-68
2 phalp2_12971
3esnk
 626 55,6% 187 1.823E-65
3 phalp2_5937
6aZNZ
 614 42,8% 182 1.363E-51
4 phalp2_5205
41m1U
 3 46,7% 182 2.546E-51
5 phalp2_7262
3WyJ7
 1 47,6% 172 2.460E-48
6 phalp2_8931
3gTAK
 6 44,6% 179 1.945E-46
7 phalp2_39194
3fUf1
 5 46,4% 170 4.958E-46
8 phalp2_20114
23hwu
 1 41,7% 189 1.727E-45
9 phalp2_24438
4y2d5
 7 41,6% 185 5.330E-44
10 phalp2_8567
1JfUc
 23 40,2% 179 9.940E-44

Domains

Domains [InterPro]
Ami2
Unannotated
Representative sequence (used for alignment): 3o2Gm (272 AA)
Member sequence: A0A8S5R1G2 (264 AA)
1 272 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01510

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct6d71
[NCBI] 		2826298 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015797 [NCBI]
CDS location
range 57523 -> 58317
strand +
CDS
ATGTCTCAAAGTAAATTAGTAAATTACATTAAACTATCACCTCATTGTACAAAGCCTAGACAAGGCCGGATTAAGGGCATCAGTATTCATACTATGGCGGGGCCTGGTTCTGTTGAAGGTTGTGGACAAGTTTTTCAACAAAGAGAAGCTTCTTCTCATTATGGTATTGGGCCAGATGGTAGAATTGGTCAATATGTTCTTGAAGAAAATCGTGCTTGGTGTACAAGCCATAAAGTAGACCATGAAGTAGTTACTATTGAAGTATCTAGTATTCAAAGTTATAAAGAACCTTATGAATGTACTAAAAAAGCATACGTTGCTCTAATTAATTTATGTGTGGATATTTGTAAACGTAATGGCATCAAGAAGCTTATTTGGAAAGAAGGAAAGCAATATTGTCCAGCTTTTACAGGTAATTGGGCGGTGTGCAATATGGTACCACATAGATACACTAGGCCAGACAAGTCTTGTCCTGGTAATTATTTGTTCAGTAAATATGGTGAGATTGCGGCAGAAGTAAATAAGCGTTTACAGGCCACCACAAAGCCCGTAGAGGAGGTTGAAGAAGATATGGATATAAACACTTTCATTAAAGAAATGACTCCTGAGCAGGCATATACGCTGTTACAAAAGGCTTCTCAATACGTTGCTTCTAAGCCTGAACCTGATTGGTCTAAGCAAGAAGGGCATTGGAATAAAGCAACTCAACAGAAGCTAGTTAATGGTGAAGCGCCTGAAGGATTCTTAAAGCGTGATGAATTTATTGCGGTTATGGGGAGAAAAGGGCTGATTTAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (3o2Gm) rather than this protein.
PDB ID
3o2Gm
Method AlphaFoldv2
Resolution 91.61
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50