Protein

Protein accession
A0A8S5R0W5 [UniProt]
Representative
8cxQA
Source
UniProt (cluster: phalp2_20202)
Protein name
Lysozyme family protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 87% (predicted by ML model)
Protein sequence
MSKAVTVRFGPGGLQKIQLYVTKKTAKKTASQVRKLTGADVVINASLYDSNKWVPNCDVKADGKVLNDDKYSYRGLGWNSGEGVFHVVTSGEMKNYDNFLSCVLLVWNGVAYPYHADAAVSRRGGRTVIIGLKDGSTVLRCFPDGNLSKTPKELQTALLGEFPTVDWALMLDGGGSVQLSQEGDEYIYSTRRVHNYLCFWRKQTDSCPYPEPTALVRQGSSGDGARWVQWQLQRHGGDLAVDGSFGAESDRTLRAFQLAYGLEVDGICGPATRARLKAEREEKTVRAVLFAAASQVGVTESPAGSNCVKYNTAYYGRKVSGNAYPWCMAFVWWVFRQAGMSLYKTASCSALVGRYKAQAPGQVIRGNYRPGDIVFFDFTGKRTKTEHVGIVESVAADGTLTTIEGNTGTGNDANGGAVMRRTRKQGLVTCAVRPGYPGE
Physico‐chemical
properties
protein length:439 AA
molecular weight:47824,6 Da
isoelectric point:9,24
hydropathy:-0,32
Representative Protein Details
Accession
8cxQA
Protein name
8cxQA
Sequence length
341 AA
Molecular weight
38066,83130 Da
Isoelectric point
8,33223
Sequence
MVREIQPSKIVLHETSKWSKKTASQVRKATGADVVINGTLFDYGAWKPNCDVKANGKVLNDDAYGYRGLGWMNGEGEFHIALSSEMNKWDNFISCVMLIYQGKDYPYIVDGAVGRSSGRTAILRRKNGKYVLWCVGEGLHNQTPAELRKSIYAKYPDIDWALMLDGGGSSQLSQEENNYVYSSRKVQNYLCFWEADTFIDKEPEGGEAMTDVRAYSLKTDGNTKLTSNFLVKEFACRDGSDVVLIHPMLPLVLQCVRMHFNAAVTVNSGYRTVAYNQKVGGVTKSQHCLGTAADITVAGHTPAEVKTFLRQLMPDWGGIGVYAKQNFVHVDMRREKADWTG
Other Proteins in cluster: phalp2_20202
Total (incl. this protein): 265 Avg length: 347,1 Avg pI: 8,70
Protein ID Length (AA) pI
8cxQA 341 8,33223
139Si 340 9,25020
13Bud 341 9,48854
13CDJ 340 9,04628
13ueB 341 9,50034
1kfPo 340 9,25368
1naBG 463 5,29429
1nbMa 339 9,42529
1rlEH 389 5,64413
2lPrk 447 7,13144
2nXZ5 324 9,03178
38OCB 338 9,37688
3AsbT 341 9,26748
3GQxm 444 6,37525
3WGfr 353 9,15143
3lU2v 337 9,65422
3lo21 458 5,22193
3loma 457 5,44634
3lpxk 457 5,60037
3nDpK 337 8,71479
3nE4N 458 6,09828
3nI6D 406 5,39927
3nJtF 340 6,93097
3o1H4 452 5,14162
3o6Iy 265 9,37120
3o9z5 279 8,65670
3oYMK 343 8,93404
3pB2g 319 6,00256
3pFPo 444 6,56299
3pICM 447 7,62054
3piYR 339 9,61954
3sra3 340 9,28656
3t3Yg 340 9,45450
3tDx6 337 9,32247
3tQe5 338 9,21667
3tuBI 339 9,42761
3uyvG 397 6,39947
3vL4G 341 9,45708
3wka3 340 9,46597
3wmsq 341 9,59917
3wtRn 341 8,34345
3xK1I 340 9,48106
3yDyO 341 9,66473
4VDr5 457 5,08711
5JV3K 339 9,29906
5KJbl 341 9,73313
5KPB8 327 9,01650
5KlF1 341 9,31795
5M1ws 312 9,42194
5N3b9 314 9,49776
5NO1i 341 9,46952
5NOzR 339 9,44921
5NoB6 341 9,50072
5NvUN 312 9,46159
5O32d 341 9,33633
5ODMb 339 9,25735
5OLD8 337 9,44476
5OQtT 340 9,30944
5OhA4 341 9,35999
5PKk5 446 6,80007
5QWPp 339 9,30970
5QeXz 341 9,44476
5Qk6G 339 9,49834
5RLzy 354 9,18734
5Rl68 446 6,08418
5S7J9 447 6,76136
5Sam6 341 9,64262
5SaoK 338 9,34329
5Soqm 340 9,56119
5SvWg 444 6,37918
5Swt3 329 9,60381
5TlbK 341 9,51129
5UGZq 449 6,56203
5Uw3g 446 6,37957
5VDTV 339 9,29906
5VGEO 337 9,43277
5Vgbp 341 9,41079
5W2Ra 341 9,11256
5W8p9 337 9,60523
5WXlS 341 9,56010
5XDY4 340 9,52516
5Xlck 341 9,51297
5Y9QS 341 9,64565
5YftD 449 6,80007
607em 341 9,54972
60J5n 337 9,27341
60X7t 341 9,61644
610Gf 444 7,13218
617JW 337 9,45869
61LYp 458 5,53461
61iny 341 9,40660
61kNC 341 9,53747
61vNv 340 9,46075
622nT 341 9,51265
62Ktr 339 9,50053
62Lbt 337 9,42194
62Vbc 341 9,47268
636xE 341 9,35625
63pwq 339 9,48912
64Jfd 341 9,53553
64ixg 341 9,37120
654kg 341 9,31937
65Hze 341 9,70895
66F8D 341 9,58389
66Fm6 447 6,56163
66T7Y 312 9,43593
66TEb 449 6,56351
66jFo 339 9,45121
67AF6 278 6,74226
67xP9 438 9,43123
68c4C 341 9,29932
68nFR 278 6,74187
68zQ9 344 9,29848
690Ut 340 9,37391
69j9F 341 9,28869
6aAMB 340 9,61515
6ajeg 341 9,65325
6alJy 349 8,57895
6axoE 446 6,23441
6bOp1 339 9,60232
6bRyW 337 9,60503
6chy3 341 9,51362
6cuXz 341 9,53715
6dep8 339 9,58595
6f52c 337 9,38029
6fDsi 339 9,38880
6fGws 337 9,29823
6fl71 341 9,38997
6fpOJ 341 9,51226
6g5XY 337 9,46301
6hndl 341 9,64262
6inc7 341 9,60361
6ipB0 449 8,06159
6j3Wc 339 9,48912
6jBbq 449 7,71438
6jLg1 329 9,27624
6kE1s 341 9,27902
6kOxV 447 6,51860
6klt5 341 9,73700
6ktkj 278 6,74022
6l9mf 340 9,26709
6lBPL 340 9,56874
6lVpl 449 6,51934
6m315 341 9,65106
6mbRP 341 8,33694
6nHBs 278 6,74226
6nRtL 337 9,55384
6nT08 339 9,38848
6o6ae 339 9,54759
6oUnf 337 9,42027
6oeyr 341 9,50053
6p42L 341 9,53863
6pSxV 341 9,41814
6pspz 278 6,82724
6qGK1 337 9,36747
6qMNF 314 9,50884
6qMmC 326 9,57841
6qN4A 340 9,59162
6qOae 339 9,54617
6qqG4 339 9,25735
6r0Mp 341 9,24749
6r1xM 337 9,71676
6r205 341 9,60587
6r4tk 339 9,53682
6rdc0 341 9,65106
6rfvG 341 9,28869
6s23t 341 9,52412
6sApc 341 9,34916
6sFjM 339 9,51194
6sI16 339 9,32988
6sOEa 333 9,64178
6sbVI 447 7,13167
6skNh 340 9,55223
6tcT4 341 9,65080
6tmXm 444 8,06153
6uK95 314 9,52019
6ugXm 339 9,43870
6v115 341 9,59304
6v9v2 327 9,63314
6vMps 312 9,46146
6wBhB 312 9,55352
6wJsa 341 9,17367
6wOst 341 9,39545
6wqUK 406 6,46353
70ih0 500 5,52688
75UrX 336 9,19179
7KyRu 397 6,00847
7VqVV 444 7,18447
7WD4j 340 9,67382
7WjDe 327 9,46391
7XUwo 349 6,65695
7XzlX 340 9,60387
7YYEY 342 9,66093
7YZMV 339 9,25561
7YZSz 340 9,47171
7YZpZ 342 9,67227
7ZF1N 446 6,56390
80OP7 341 9,70167
81XKU 447 7,62094
81XUX 340 9,58769
821lT 444 6,37599
83Ucn 447 7,10495
83klC 447 7,61815
84Nb0 252 9,64152
84NuF 344 9,63984
84du7 447 6,79694
86gGI 255 9,48093
86kNg 264 9,64333
86rCW 340 9,51761
87Iw9 340 9,74009
87pjc 354 9,54024
88oZS 340 9,63939
8b7sK 339 9,30854
8bzqA 340 9,61432
8cw0k 340 9,68465
8cwXU 458 5,63305
8cyZj 340 9,54765
8eY9f 444 6,56106
8euXG 337 9,29926
8f42d 340 9,45334
8f7PI 342 9,63578
8fuHP 338 9,29881
8ic0x 447 6,56294
8jCJb 458 5,41246
8jpjs 458 5,22733
8lgOq 444 6,22151
8lxas 444 6,56316
8lyQR 340 8,91116
8m4Eh 340 9,63939
8mQnU 342 9,62050
8md6e 340 9,54991
8nOMs 340 9,52922
8oNlU 340 9,66305
8oUAO 340 9,63939
8ou75 444 6,08418
8qfWl 342 9,72997
8r04R 348 9,49589
8r0lL 340 9,54765
8romD 340 9,49905
8tMYi 337 9,29926
8tSjj 347 9,75157
8tSyF 340 9,66305
8tg23 349 8,73548
8uIWF 273 8,60474
NOOX 444 6,21906
NyvZ 444 6,79581
Osl0 446 6,56606
p0Qm 458 5,63572
xBTE 339 9,51162
W6AT95 136 8,91902
A0A2I7QVH5 117 9,00199
A0A2I7QXH2 117 9,00180
A0A2I7R3E7 117 9,00199
A0A2I7R4D5 117 8,76488
A0A2I7R4K7 117 8,76488
A0A2I7R851 117 9,18244
A0A2I7RAD4 117 9,00180
A0A2I7RED8 117 9,00180
A0A2I7RSG4 117 9,00180
A0A2I7RT67 117 9,00199
A0A2I7RTC4 117 9,00199
A0A8S5N3D7 438 9,30667
A0A8S5N9S5 133 9,19888
A0AA47KWT8 136 8,91902
Similar Clusters

No similar clusters were found for representative 8cxQA.

Domains

Domains [InterPro]
NAGPA
PET_M15
Representative sequence (used for alignment): 8cxQA (341 AA)
Member sequence: A0A8S5R0W5 (439 AA)
1 341 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08291, PF09992

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctPVE25
[NCBI] 		2826649 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015779 [NCBI]
CDS location
range 4021 -> 5340
strand -
CDS
ATGAGTAAGGCGGTGACGGTGCGCTTCGGCCCGGGCGGCCTGCAGAAGATCCAGCTCTATGTGACGAAGAAGACCGCCAAGAAGACAGCCAGCCAGGTCCGCAAGCTCACGGGGGCCGACGTGGTCATCAACGCCAGCCTCTACGACTCCAATAAGTGGGTCCCCAACTGCGATGTCAAGGCGGACGGGAAGGTCCTGAACGATGACAAGTACAGCTACCGGGGTCTGGGCTGGAACAGCGGGGAGGGCGTCTTCCACGTTGTCACCAGCGGCGAGATGAAGAACTACGACAACTTCCTCAGCTGCGTCCTGCTCGTCTGGAACGGCGTGGCGTATCCCTATCACGCCGATGCCGCCGTCTCCCGGCGGGGCGGACGGACCGTGATCATCGGCCTCAAGGATGGCAGCACGGTCCTGCGCTGCTTCCCGGATGGCAATCTGTCCAAGACCCCCAAGGAGCTCCAGACGGCGCTCCTTGGGGAGTTCCCCACGGTGGACTGGGCCCTGATGCTGGATGGCGGCGGCAGCGTGCAGCTCTCCCAGGAGGGGGACGAGTACATCTACTCCACCCGGCGGGTCCACAACTACCTCTGCTTCTGGCGGAAGCAGACGGACAGCTGCCCCTACCCGGAGCCCACGGCGCTGGTGCGGCAGGGGAGTTCCGGAGACGGGGCCCGGTGGGTCCAGTGGCAGCTCCAGCGCCATGGCGGAGATCTGGCGGTGGACGGCAGCTTCGGGGCGGAGAGTGACCGGACCCTGCGGGCCTTCCAGCTGGCCTATGGCCTGGAGGTGGACGGCATCTGCGGCCCGGCCACCCGTGCCCGCCTGAAGGCGGAGCGGGAGGAGAAGACGGTGCGGGCCGTACTCTTCGCGGCCGCCAGTCAGGTGGGCGTCACGGAGAGCCCCGCCGGTTCCAACTGCGTGAAATACAATACCGCCTACTATGGCCGCAAGGTCAGCGGCAATGCCTATCCCTGGTGCATGGCTTTCGTCTGGTGGGTCTTCCGGCAGGCGGGGATGTCCCTTTACAAAACGGCGTCCTGCAGCGCCCTGGTGGGCCGGTACAAGGCGCAGGCCCCCGGGCAGGTCATCCGGGGGAATTACCGGCCCGGAGACATCGTGTTCTTCGATTTCACGGGAAAACGGACCAAGACGGAGCACGTGGGCATCGTGGAGAGCGTGGCGGCGGACGGAACCCTCACCACCATTGAGGGCAACACCGGCACGGGCAACGACGCCAACGGCGGCGCTGTCATGCGGCGGACCCGGAAACAGGGGCTCGTCACCTGCGCCGTGAGACCGGGGTATCCGGGCGAATAA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (8cxQA) rather than this protein.
PDB ID
8cxQA
Method AlphaFoldv2
Resolution 92.27
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50