Protein

Protein accession
A0A8S5QVB0 [UniProt]
Representative
6ffn9
Source
UniProt (cluster: phalp2_5941)
Protein name
Cell wall hydrolase autolysin
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MLRIAIDAGHYKGTPGRRCLAALDPAQTGEWELNRRVADKLEELLRRYDCQVLRVDDKTGDRLIDLWDRVAAANGWPADVYLSIHHNAGIRGGSGEGCVVYTAPGCQAKSKALQKAVYGAVVSRTGLVGNRATPMMERGLYVLRRTTMPAILIECGFMDSSTDVPVILTAYFAEQVADGLLAALVEVFNLSERKEVRERMRYTKRGGAHIVEVPAKDFAVRLVDKAKKSAYSGNYCNAGFFGNYNEGADKFTLPVGHTVATMETDNKWVNHYCEERGKVSGGKLVYAEPGRTETTLFIRGGKADMGEVSAPPEGCAYAIAGVPVLRQGKAVSWATAKAQGWEASSLYATWHIFAGYGQDRSRVTVVALKTTTGNLISSGEGAKKLAALGLREAIKLDGGGSTILRVGGKTPVSTAGDRRICTVLTFGGDPYPVPTRTLTKGKRGEDVKWLQWELNDRGFSCAVDGSFGPGTKEALMAYQVSAGLVPDGSCGPATKAELLK
Physico‐chemical
properties
protein length:500 AA
molecular weight:53811,8 Da
isoelectric point:9,01
hydropathy:-0,22
Representative Protein Details
Accession
6ffn9
Protein name
6ffn9
Sequence length
500 AA
Molecular weight
53303,42720 Da
Isoelectric point
9,33027
Sequence
MLKIAIDAGHYKGTPGRRCLAALDPAQTGEWELNRRVADKLEELLAGYDCQVLRVDDRTGDRLIDLGDRVAAANGWPADVYLSIHHNAGIKGGSGGGCVVYTAPGCQAKSKALQRAVYGAVVSRTGLVGNRATPMMERGLYVLRRTKMPAILIECGFMDSSTDVPVILGPYFAGQVADGLLAALMEVFNLAERKEVRERMSYTKRGGAHIVEVPVKDFAVRLVDKAKKTAYSGNYCNAGFFGNYNEGRDKFTLPVGHTVATMATDNRWVNHYCAQRGKVSGGKLVYAEPGRTETTLFVRGNLADMGDLSAPPEGCAYAIAGVPVLRHGKAVSWATAKAQGWDASSLYATWHIFAGYGQDRSRVTVVALRTTTGNLISSGEGAKKLAALGLREAIKLDGGGSTILRVSGKTPVCTAGNRRICTVLTFGGNPYTAPTKTLVKGNRGEGVRWLQWELNDRGFACAVDGSFGPGTKEALMAYQVSAGLVPDGSCGPATRKALMG
Other Proteins in cluster: phalp2_5941
Total (incl. this protein): 61 Avg length: 497,7 Avg pI: 6,70
Protein ID Length (AA) pI
6ffn9 500 9,33027
1khQv 500 8,93630
1m6Ja 509 6,13977
1mht5 498 6,18695
1ncBj 505 6,33950
1nmKH 509 5,99591
2lYAc 495 6,14159
3GHjI 509 6,01046
3lPtS 509 6,29818
3lpIX 499 6,20178
3mjfp 510 6,40089
3osYF 509 6,80661
3pvJm 495 6,24231
3qFUQ 510 5,65709
3qgFl 509 6,35690
3qhgP 509 5,82448
3sAxm 509 7,59258
3sYEa 510 6,48996
3scWR 493 6,12317
3uLGB 493 5,36716
3uwwn 507 5,68250
3vPeJ 500 9,36308
3wAeJ 494 6,44011
3yLvR 505 6,48348
3yqH6 509 6,19991
4z33R 465 5,78623
4z33n 436 5,96874
4z7tX 496 6,07730
5KEVR 426 5,99404
5L9kT 493 5,94044
5LgsZ 500 9,24362
5MBJf 500 9,39557
5O9U2 499 5,98625
5PpVf 498 5,60997
5Q93o 500 9,34374
5QdYh 500 9,25129
5VdnX 493 5,84165
60a3U 494 6,69230
659ty 500 5,88792
68WMn 500 9,23015
69mne 497 6,73885
6aBFW 493 5,94220
6c0CU 495 5,58866
6cIch 494 6,69020
6gyWa 498 6,00023
6kS6z 497 5,61259
6udPP 500 9,10166
6ueOL 497 5,56393
6wcsB 498 5,93180
7WMqj 493 6,30449
7YUEp 493 5,78140
7YXuV 494 7,58888
85D3F 489 5,88559
86lcT 493 6,30449
8hPb1 509 5,99676
8lGUd 497 5,93782
8qV6m 500 8,85662
8sABI 509 7,10961
OGJO 509 5,87172
Om1v 509 6,14170
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_31453
3sz7J
 9 49,5% 343 1.205E-160
2 phalp2_36520
1qvSh
 1 32,2% 459 1.869E-64
3 phalp2_34286
3lMrj
 2 28,5% 532 9.530E-44
4 phalp2_30018
2o9Ij
 3 29,6% 445 1.776E-35
5 phalp2_32481
1c5or
 14 23,3% 453 3.667E-19

Domains

Domains [InterPro]
Ami3
NAGPA
PG_1
Representative sequence (used for alignment): 6ffn9 (500 AA)
Member sequence: A0A8S5QVB0 (500 AA)
1 500 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01471, PF01520, PF09992

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct5co22
[NCBI] 		2826294 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015735 [NCBI]
CDS location
range 21395 -> 22897
strand -
CDS
ATGCTGCGCATCGCCATTGACGCGGGGCACTACAAGGGGACGCCGGGGCGGCGGTGTTTAGCCGCCCTGGACCCCGCCCAGACGGGAGAGTGGGAGCTCAACCGCCGGGTGGCGGACAAGCTGGAGGAGCTGCTGAGGCGGTATGACTGCCAGGTCCTCCGGGTGGACGACAAGACTGGGGACAGGCTGATCGACCTGTGGGACCGGGTGGCGGCGGCCAACGGCTGGCCCGCGGACGTGTATCTGTCCATCCACCACAACGCCGGGATCCGCGGCGGCAGCGGCGAGGGCTGCGTGGTCTACACGGCCCCCGGCTGTCAGGCCAAAAGTAAGGCCCTCCAGAAGGCCGTTTACGGTGCCGTGGTGAGCCGCACAGGGCTGGTGGGCAACCGGGCCACCCCCATGATGGAGCGCGGCCTGTACGTCCTCCGGCGCACCACCATGCCCGCTATCCTGATCGAGTGCGGGTTCATGGATTCGTCCACCGACGTGCCTGTGATCCTGACCGCCTATTTTGCGGAACAGGTGGCGGACGGCCTGCTGGCTGCGCTGGTGGAGGTATTCAACTTGAGCGAGCGCAAGGAGGTGCGGGAGCGGATGCGCTATACCAAAAGGGGCGGAGCCCACATCGTGGAGGTGCCCGCGAAAGACTTTGCGGTGCGGCTGGTGGACAAGGCCAAGAAGTCGGCCTATAGCGGCAACTACTGCAACGCCGGGTTCTTCGGGAACTACAACGAAGGAGCCGACAAGTTTACCCTCCCCGTGGGCCACACTGTGGCTACCATGGAGACGGACAACAAGTGGGTCAACCACTACTGCGAGGAGCGGGGCAAGGTGTCCGGCGGCAAGCTGGTCTACGCCGAGCCGGGACGGACGGAGACCACCCTGTTCATCCGGGGCGGCAAAGCGGACATGGGAGAGGTGAGCGCGCCCCCGGAGGGCTGCGCCTACGCCATCGCGGGCGTGCCTGTGCTGCGGCAGGGCAAGGCGGTGAGCTGGGCCACGGCAAAGGCTCAGGGCTGGGAGGCGTCCAGCCTGTACGCCACCTGGCACATCTTTGCGGGGTACGGACAGGACCGGAGCCGCGTCACGGTGGTGGCCCTGAAAACCACCACGGGCAACCTGATCTCCAGCGGCGAGGGAGCCAAAAAGCTGGCCGCTTTGGGGCTGCGGGAGGCCATCAAGCTGGACGGGGGCGGCAGCACCATCCTGCGGGTGGGGGGCAAGACGCCGGTGTCCACGGCTGGTGACCGGCGGATCTGCACGGTGCTGACCTTCGGGGGGGACCCGTACCCCGTGCCCACGCGGACGCTGACAAAGGGTAAGCGGGGGGAGGACGTGAAGTGGCTCCAGTGGGAGCTGAACGACCGGGGGTTCTCCTGCGCCGTGGACGGCAGCTTCGGCCCGGGCACTAAGGAGGCCCTGATGGCGTATCAGGTGAGCGCGGGGCTGGTGCCGGACGGCAGCTGCGGACCGGCGACGAAAGCAGAACTCTTAAAATAA

Gene Ontology

Description Category Evidence (source)
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity molecular function None (UniProt)
GO:0009253 peptidoglycan catabolic process biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (6ffn9) rather than this protein.
PDB ID
6ffn9
Method AlphaFoldv2
Resolution 93.54
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50