Protein

Protein accession
A0A8S5QPK8 [UniProt]
Representative
69s4u
Source
UniProt (cluster: phalp2_11199)
Protein name
SH3 domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 96% (predicted by ML model)
Protein sequence
MIQASALIALFKRMLDEHWAYEWGAAREGCVDCSGAFVWAYRQLGASIEHGSNSIVRLRVGEYVPIAEAKPGYAVFKMRAWRESDSGNRWFGQQPGDVYHIGLMGDDGKVLNAQSTKTGFVASDAAGWAFAAPLKDVICKEGDGKMYGNATVSVTSGYLNIREGASTRSKVIAKAENGARVNIIREAGGTGWVFGALESGEAGYMSSEYLVEDALKSGDQGETSGETPTTTTLRRSDGVYITLAGKWALAED
Physico‐chemical
properties
protein length:252 AA
molecular weight:27085,0 Da
isoelectric point:5,38
hydropathy:-0,24
Representative Protein Details
Accession
69s4u
Protein name
69s4u
Sequence length
182 AA
Molecular weight
20003,49140 Da
Isoelectric point
7,75786
Sequence
MIDVNKLLDLFERMEREHWAYELGAAREGLVDCSGAFVWAYKQMGGSIEHGSNSIYHLRVGKVVPVGEAKPGYAVFKMRAWREEDRGNRWYGESPGDCYHIGLMGRDGKVLNAQGVKTGFVASDAKGWAFAAPLNAVKYETKGDEKMFGNATVSVTSGYLKILVGAGSAVERSFRTESVNVV
Other Proteins in cluster: phalp2_11199
Total (incl. this protein): 23 Avg length: 222,8 Avg pI: 6,19
Protein ID Length (AA) pI
69s4u 182 7,75786
3e0XH 192 6,89226
3uZ9y 260 5,09365
40FNg 204 7,70131
4L6z8 192 8,13283
5KW7D 252 5,22040
5R46b 252 5,34829
5RtQk 252 5,10803
617od 256 4,67151
656tV 257 5,03039
65x2F 257 5,28139
68QoH 253 5,62214
698EF 256 4,82111
6fEqf 168 7,64413
6pXV0 256 5,12696
6qIh2 167 7,03811
6tWfA 257 5,24558
84Mla 168 8,56606
86s93 171 6,31142
8bH28 256 4,97548
8fAKx 194 8,94288
8tqPB 171 6,41010
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_17568
6bVpI
 247 32,6% 196 3.337E-39
2 phalp2_17704
71inw
 139 29,2% 219 6.306E-36
3 phalp2_32200
6Xp2c
 36 32,9% 173 7.017E-34
4 phalp2_32958
3ZDZv
 229 30,1% 199 4.063E-26
5 phalp2_20662
7DFjx
 8 26,6% 169 1.675E-16
6 phalp2_6991
3apD5
 64 23,7% 194 2.062E-13
7 phalp2_15936
4JJEp
 1 21,0% 166 4.842E-07
8 phalp2_33418
6WYXp
 10 19,0% 231 4.842E-07

Domains

Domains [InterPro]
Unannotated
Representative sequence (used for alignment): 69s4u (182 AA)
Member sequence: A0A8S5QPK8 (252 AA)
1 182 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct8LX107
[NCBI] 		2826169 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015706 [NCBI]
CDS location
range 36226 -> 36984
strand +
CDS
ATGATTCAGGCGAGCGCGCTCATCGCGCTATTTAAGCGCATGCTGGACGAGCACTGGGCGTATGAGTGGGGCGCGGCGCGTGAAGGTTGCGTGGACTGCTCAGGGGCTTTTGTCTGGGCGTACAGGCAGCTCGGCGCGAGCATCGAGCACGGCAGCAACTCCATTGTACGTCTGCGCGTTGGCGAGTATGTGCCCATCGCGGAGGCAAAGCCGGGATATGCGGTCTTTAAAATGCGAGCATGGCGCGAAAGCGACAGCGGAAACCGCTGGTTTGGCCAGCAGCCCGGCGACGTCTATCACATCGGCCTGATGGGCGACGATGGGAAGGTGCTCAATGCGCAGAGCACAAAGACGGGTTTTGTGGCGAGCGACGCGGCGGGCTGGGCGTTCGCCGCGCCGCTCAAGGATGTGATCTGCAAGGAGGGCGACGGGAAAATGTATGGCAATGCGACGGTGAGCGTGACCAGCGGATACCTCAACATCCGCGAGGGTGCAAGCACGCGGTCAAAAGTCATCGCCAAGGCCGAGAACGGCGCGCGGGTGAACATCATCCGCGAGGCGGGCGGCACGGGCTGGGTCTTCGGCGCGCTGGAAAGCGGCGAGGCCGGGTATATGTCGAGCGAGTATCTGGTCGAGGATGCGCTGAAAAGCGGAGATCAGGGCGAGACGAGCGGCGAAACGCCGACCACAACGACCCTGCGCAGGAGCGACGGCGTGTATATCACGCTGGCGGGAAAATGGGCGCTTGCGGAGGATTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (69s4u) rather than this protein.
PDB ID
69s4u
Method AlphaFoldv2
Resolution 87.87
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50