Protein

Protein accession
A0A8S5Q5A6 [UniProt]
Representative
19m9Y
Source
UniProt (cluster: phalp2_2985)
Protein name
Membrane protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MADSLIKLIFHKNEAYITSPFGYRKSFSTAAGATGSFHNGVDYGTNCKKVPQYAIADGYIYSCGVDYAYGGAKYVWVAYPSLGVKMLHYHLDSIKVKAGQKVTAKTVIGNTGMSGRATGIHLHLGVKRLSGGDWLDAESWYKNEYKAPTAAKKKYTAGNYKVTKATVLNVRKGAGTKYAKKAFSQLTKDAQKKIVALSGERCNGYVKGLTFTISKVKGSWGKTPSGWVCLDYCERI
Physico‐chemical
properties
protein length:236 AA
molecular weight:25748,3 Da
isoelectric point:9,73
hydropathy:-0,31
Representative Protein Details
Accession
19m9Y
Protein name
19m9Y
Sequence length
460 AA
Molecular weight
51027,31570 Da
Isoelectric point
6,07162
Sequence
MKDRAKILGYVVAIILVVLLSIECLIQYKRTGEIDTNYIEEAIAVLEDVNESSTEIPGLSIEEEQELEVQEVESEAFELQGEIAYEGDAKTWNISTGNTPQLTYISQIDSRWKNHPYTSTGNSSQTIGSSGCGVASAAMIIDSIVGNVDVIELADTFVANGYRSVNNGTYWSAYRAVADQFNIGYTETSNLNAAIELLRSNHYIIASCGNGLFTTGGHYIVLYGLEGDTIKIYDPYLYNGKFETSTRRGKVTVSGNTVYCSIDNFRNYANYKQFFCYKYNVNNVVTINNTDNKVTTYGYTRYVNTNNLNLNVRSGPGTDNPVRAKLSKGTEVSVIETDGDWSRITKPTEGWVYSDYLSSANTPQVVQKVNSTVQKVNGYTTGNYKVRVNSILNVRSGAGTQYKAKTYKQLTTNARAQNKRLGNYYANGYKNGVVCTVIKVQGNWGLTASGWICLDYCRKI
Other Proteins in cluster: phalp2_2985
Total (incl. this protein): 249 Avg length: 469,4 Avg pI: 8,38
Protein ID Length (AA) pI
19m9Y 460 6,07162
138nZ 540 8,36730
13c3o 516 9,25336
19iSu 458 7,96689
1FCSI 392 9,49144
1GKhM 327 9,02507
1ktTc 467 9,63243
1o0RX 511 9,09135
1ocHY 465 5,83335
21je5 488 9,17284
21tCR 411 9,39164
21ulg 474 9,19056
234ig 438 9,43986
234k8 467 7,88656
23S9E 545 5,12576
23d3P 476 9,09683
23eJZ 411 9,41098
23etV 452 5,44849
24B5g 436 5,74411
24FZd 459 8,39999
2VaSR 406 8,77197
2Vjjv 470 9,28321
2Vkxr 476 8,74586
2m4uI 552 8,18292
2oDYv 495 7,49379
38MwK 514 8,98117
3AZXL 463 9,53250
3B5Ox 463 9,68826
3JcyR 514 8,85984
3KQdT 463 9,64539
3TEJB 423 8,98220
3TGVM 386 8,02872
3VDew 564 7,02828
3WETr 411 9,38545
3WKsZ 509 8,53292
3Wz6n 461 9,15395
3dPEv 502 4,47371
3dSEL 457 7,47571
3gWQs 453 6,39026
3kF9a 503 8,71988
3kojR 504 8,48457
3l7gS 502 7,43189
3lDK2 467 9,63881
3lMLJ 467 9,60142
3lZl7 511 9,13216
3llLh 455 8,73413
3m6sq 506 6,68417
3mkee 445 8,83934
3mqSg 467 9,72133
3mxBw 459 9,47874
3mxyg 455 8,79267
3nLgm 541 4,91688
3pXJc 503 6,68878
3pgSz 537 5,78930
3pgVA 460 9,40447
3piLZ 503 5,65761
3s9Ne 467 9,62598
3sCCc 449 9,02417
3sZ6b 462 9,60452
3saOm 463 9,61715
3sgeB 463 9,56835
3t0b8 464 8,92934
3t9ZM 463 8,59823
3tC5e 464 8,60294
3tNlJ 463 9,58524
3tn9h 467 9,58511
3trNW 463 9,57467
3tsYH 460 9,22183
3tw49 493 7,46872
3txTe 463 9,64539
3uZEE 471 8,45865
3udF9 456 8,92940
3v3Iz 494 8,89285
3vb22 459 5,79624
3vxhx 502 8,93875
3vyaU 509 9,15420
3w5QQ 461 9,09631
3wgBQ 457 4,89846
3wgBv 552 7,91615
3wgZ1 467 9,72720
3wm4X 506 8,45807
3xWN9 541 5,85745
3y2kj 471 8,82232
3y6Wb 463 8,28169
3yADL 459 7,50806
3yQcW 509 8,99194
3yiH8 463 9,62366
3yu6r 463 8,59823
41323 386 8,02872
41fOE 389 8,60074
4DBCl 562 5,55245
4L4ar 390 9,33729
4L61Z 411 9,45314
4UeQv 553 5,72553
4yaG4 457 8,48231
4ygNV 477 5,10706
4z8gm 467 9,64707
5JUst 450 7,99532
5K9LV 392 8,53950
5KRVr 376 5,49902
5L6CD 464 8,66844
5LbER 388 6,08538
5LeO9 467 9,70154
5LppR 450 8,69693
5MLBU 464 8,85526
5MVE5 460 9,21532
5NHyk 540 6,65666
5NkjJ 459 8,34300
5NlZv 540 6,66127
5Nxbe 503 8,68662
5O4sQ 460 9,19372
5Of9b 471 8,45865
5QCW8 326 8,98626
5QfSE 446 9,04429
5R6fp 464 8,56612
5RTu6 460 9,22177
5S2vR 511 8,99980
5S4uN 460 8,80543
5S6WB 455 8,93392
5SfnA 503 8,68662
5SkbL 447 9,46746
5SqFf 452 9,04313
5TMOr 503 6,29835
5TTW3 504 9,21655
5Tqtw 511 9,03578
5U1wp 492 8,26699
5UWce 502 6,68281
5UWnD 423 9,52000
5Uy0N 460 9,15259
5VCt4 502 8,81607
5VdGG 455 8,59765
5W4ys 460 8,46310
5WBlu 403 8,79512
5Whzp 467 9,68168
5XbQf 509 8,94301
5Xn4F 326 8,76552
5XuKR 503 8,61132
5YSuS 326 9,00309
5Yyz2 511 9,08045
5ZW3m 502 9,04906
5Zke9 482 8,93424
5lNU 546 5,16618
5oaM 485 9,02810
605x0 460 9,30648
60B3v 332 8,88982
60HWF 524 8,76978
60y2i 469 9,19417
61Y7b 464 8,79112
620rH 503 8,74722
62S64 501 6,67656
62Uez 459 7,50806
62pVw 504 8,85314
633gK 445 8,77042
63dmg 458 9,18760
64dxm 469 9,24788
65KoM 451 8,90136
66kP3 462 8,93907
67JJZ 326 9,12984
67SY0 456 8,73825
67Tih 461 9,24813
67VeM 445 8,83934
68oKT 508 9,09605
68vpK 503 5,63692
6ZRHS 463 9,62366
6Zt3W 467 9,64707
6aUeI 459 8,61338
6awbU 500 5,62873
6b4iF 502 8,86803
6b6kd 451 8,84011
6bH9u 445 8,83934
6bW3q 504 8,86300
6bbRR 504 6,15802
6bzRn 482 8,79808
6ceO7 450 8,43280
6d98l 471 8,59804
6eqps 458 8,79512
6hQzL 456 8,99477
6hYvW 494 9,02005
6hf6e 346 5,08660
6hips 511 8,99980
6ihrN 466 9,56184
6iloj 471 8,59810
6imHq 504 9,05389
6kZuQ 467 9,66776
6lnZs 502 5,64129
6ltNR 504 9,09148
6m7fA 509 9,15846
6mG1u 471 7,99558
6mMKR 471 8,84688
6nBa9 462 8,32907
6nidd 497 8,86287
6o55N 501 6,68088
6oPLd 362 9,66247
6oU3B 502 6,68088
6p8Ie 461 9,20778
6pKSt 459 9,05022
6pV7X 502 8,94410
6pxwQ 445 8,38316
6qqr3 459 8,92960
6rJ8k 513 9,02108
6rvr0 503 8,85797
6sMIi 505 8,85301
6sof3 511 9,25639
6sse0 392 8,65683
6sxJv 516 8,69461
6t81H 537 6,38395
6ubyp 463 8,27763
6v35F 446 6,91307
6vbDv 462 9,66009
6vh8o 471 8,59804
6vkdq 514 8,68126
6wHhF 498 5,85063
6we0J 464 8,75824
6wiSY 509 9,04609
7JCEh 392 9,66531
7JCxA 404 9,45430
7JF0S 474 9,10875
7JGq0 469 4,97611
7Nvo8 511 9,02017
7Vli7 492 7,99332
7Vp4H 552 7,91615
7WHtm 511 8,85991
7XBTd 326 8,78983
7YKwV 512 8,78151
81ARy 463 9,56822
86M5Y 466 9,64526
8bWJN 494 9,15072
8fdt1 467 9,69503
8hmfM 503 6,14273
8icH1 430 8,73542
8ll0E 497 8,95493
8pWVm 549 5,12423
9XOk 508 7,94890
CNpw 463 9,64713
NEr9 463 9,57879
a1Ux 394 9,60645
a601 537 5,40587
gpZM 363 4,79070
nbYf 503 5,54705
norM 516 9,09019
nwlA 502 6,84850
oipo 504 8,35383
ok2u 385 9,74428
op0P 449 5,66164
orC1 511 9,29397
qlmG 502 8,81607
A0A8S5PBL9 492 6,66832
A0A8S5SSC4 511 9,12893
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_23106
4ysmN
 5 45,3% 293 1.464E-92
2 phalp2_10169
ooyj
 1 35,2% 352 2.744E-87
3 phalp2_37227
24Gxi
 25 24,2% 367 9.552E-39
4 phalp2_9514
139E1
 4 23,4% 376 7.606E-30

Domains

Domains [InterPro]
Disordered region
Unannotated
PET_C39
SH3_3
Unannotated
Representative sequence (used for alignment): 19m9Y (460 AA)
Member sequence: A0A8S5Q5A6 (236 AA)
1 460 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF08239, PF13529

Taxonomy

  Name Taxonomy ID Lineage
Phage Siphoviridae sp. ct0uL16
[NCBI] 		2825299 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015578 [NCBI]
CDS location
range 10555 -> 11265
strand +
CDS
ATGGCTGATTCACTTATTAAACTTATTTTTCACAAAAACGAAGCTTACATAACAAGCCCGTTCGGCTACCGGAAAAGCTTCAGTACGGCGGCCGGGGCAACCGGCAGTTTTCACAATGGAGTTGATTACGGAACGAATTGCAAAAAGGTTCCGCAGTATGCAATCGCGGACGGGTACATCTATTCGTGCGGCGTTGACTACGCCTACGGCGGCGCAAAATACGTTTGGGTTGCTTATCCGTCGCTCGGTGTTAAAATGCTCCATTATCATCTTGACAGTATCAAGGTGAAAGCAGGGCAAAAAGTAACAGCAAAAACGGTTATCGGCAACACCGGAATGAGCGGCAGGGCAACCGGTATACACCTGCATCTGGGCGTTAAACGGCTTTCGGGCGGAGATTGGCTTGACGCTGAAAGCTGGTACAAGAACGAGTACAAAGCACCGACAGCGGCGAAAAAAAAGTACACTGCCGGAAATTACAAGGTTACGAAAGCGACCGTCCTCAATGTCCGCAAAGGCGCCGGTACAAAGTATGCAAAAAAAGCCTTTTCGCAGCTTACAAAGGACGCGCAGAAAAAAATCGTTGCACTTTCCGGCGAAAGATGCAACGGATATGTCAAAGGGTTAACTTTTACTATTTCAAAGGTAAAAGGCAGCTGGGGCAAAACGCCGAGCGGTTGGGTGTGCCTGGATTATTGCGAGAGGATTTGA

Gene Ontology

Description Category Evidence (source)
GO:0004222 metalloendopeptidase activity molecular function None (UniProt)
GO:0031640 killing of cells of another organism biological process None (UniProt)
GO:0042742 defense response to bacterium biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (19m9Y) rather than this protein.
PDB ID
19m9Y
Method AlphaFoldv2
Resolution 80.36
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50