Protein

Protein accession
A0A8S5Q4T0 [UniProt]
Representative
1kc1M
Source
UniProt (cluster: phalp2_36492)
Protein name
CHAP domain protein
Lysin probability
100%
PhaLP type
endolysin
Probability: 98% (predicted by ML model)
Protein sequence
MSVLRITEPDYANRYYKHVSSGGVNECIRVNGNSVLPNCVGYAWGAWYEMTGVRPKLSRRNAKEWYGYTADGYRRSSVPELGAVACWNGRYGHVAIVVGIFKDYIVVAQSNYGGNRWEKVRCYKYGKGYKSHGGNTAFQGFICLPDKYRVTVADKTANTSGGNVKTWNLSGIYGKKPKVFTTKCALNMRDYPSTTGKVKEVAPKGRKLFYYGYGAKVGNICWYYVQDAVTKKEGYVYGGKYNSGVAPYLSNARP
Physico‐chemical
properties
protein length:254 AA
molecular weight:28391,0 Da
isoelectric point:9,69
hydropathy:-0,51
Representative Protein Details
Accession
1kc1M
Protein name
1kc1M
Sequence length
254 AA
Molecular weight
28237,64490 Da
Isoelectric point
9,59929
Sequence
MSTLRITEPSYANKYYKHVNYGGVNECLRINGNSCLPNCVGYAWGAWYEMMGVRPKLSRANAKNWYGYTSDGYRRSSTPELGAVACWGGNGYGHVAIVIGIYSNYIVVAQSNYGGKRWEKVRCYKYGKSYKSHGGNTAFQGFICLPNQYRVTVAEKESNSTGGTVRTWNMSSKFKNGKVFTTKCALNMRSYPSTSGAVKEVVPTNHKLYYYGYGAMNGKIAWYYVLDKQTGKEGYVYGGVQGSGVAPYLKNANP
Other Proteins in cluster: phalp2_36492
Total (incl. this protein): 27 Avg length: 251,7 Avg pI: 9,41
Protein ID Length (AA) pI
1kc1M 254 9,59929
13DoQ 296 9,62959
3PP07 299 4,98196
3gH0m 246 8,04864
5RQaC 254 9,72024
5T1RY 254 9,61386
5UjeF 254 9,66408
5W6Vt 254 9,72024
5XhTB 254 9,43045
5YekN 254 9,68304
60QDD 273 9,90442
61Lh0 205 9,83841
64sO3 175 9,98133
65aNH 203 10,02491
6cKaX 254 9,62534
6rTMi 267 9,82074
6si3d 252 9,86058
7WUhA 252 9,49318
86EYK 254 9,72024
86bn0 265 9,51639
89Xv9 255 9,30068
8n7J7 252 9,48093
8nbkk 255 9,30068
8qY6j 254 9,70812
8smn8 255 9,30919
8smre 251 9,37649
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_1456
1Ix8Z
 1 37,7% 249 2.131E-47
2 phalp2_11680
1Nyjf
 74 33,5% 185 1.887E-33
3 phalp2_15440
410GZ
 43 30,0% 223 3.873E-19
4 phalp2_19753
7DRZn
 3 28,5% 217 2.528E-15
5 phalp2_23401
63yXA
 1 23,8% 273 1.254E-13
6 phalp2_27001
8pvaU
 3 22,8% 258 3.020E-09
7 phalp2_7629
5XNQW
 23 22,9% 187 1.754E-08
8 phalp2_29169
7vSPi
 45 22,8% 188 5.892E-06

Domains

Domains [InterPro]
CHAP
Unannotated
Representative sequence (used for alignment): 1kc1M (254 AA)
Member sequence: A0A8S5Q4T0 (254 AA)
1 254 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF05257

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctza028
[NCBI] 		2825289 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015569 [NCBI]
CDS location
range 8985 -> 9749
strand +
CDS
ATGAGTGTTCTTAGAATTACAGAGCCTGACTACGCAAACAGATACTACAAGCATGTAAGTTCAGGCGGAGTGAATGAATGTATTAGAGTCAATGGGAATTCAGTGCTGCCAAACTGTGTTGGATATGCGTGGGGTGCATGGTATGAAATGACTGGCGTAAGACCTAAGCTGTCTCGTAGAAATGCAAAGGAATGGTATGGCTATACAGCTGACGGATACAGACGAAGCAGTGTCCCTGAACTTGGTGCTGTAGCGTGCTGGAATGGAAGATACGGTCATGTCGCAATTGTAGTCGGTATCTTCAAAGACTATATCGTTGTTGCACAGTCCAACTATGGCGGTAACAGATGGGAAAAGGTAAGATGCTACAAGTATGGAAAAGGGTACAAGTCACACGGGGGCAATACAGCCTTTCAGGGATTCATCTGTCTGCCTGACAAATACAGAGTTACAGTTGCTGACAAGACAGCAAACACATCAGGCGGTAATGTAAAGACGTGGAACTTGTCAGGTATCTATGGCAAGAAGCCTAAAGTGTTTACAACAAAGTGTGCATTGAATATGCGTGACTATCCAAGTACAACAGGCAAGGTCAAGGAAGTTGCACCAAAAGGAAGAAAGCTGTTCTACTATGGCTATGGTGCAAAGGTTGGAAATATCTGCTGGTACTATGTTCAGGATGCTGTAACAAAGAAGGAAGGCTATGTGTATGGTGGCAAGTATAACAGCGGTGTAGCACCATACCTGAGCAATGCAAGACCATGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (1kc1M) rather than this protein.
PDB ID
1kc1M
Method AlphaFoldv2
Resolution 86.25
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50