Protein

Protein accession
A0A8S5PYR6 [UniProt]
Representative
5YKpd
Source
UniProt (cluster: phalp2_6201)
Protein name
Peptidoglycan hydrolase
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MNKQEFLSLIVPLAQAEAKRRKDTGTGFVLPSVCVGQAALETGWGGSSLMTKANAFFGIKATASWGGKVFSSKTQECYDSVTYTTITAAFRAYDTPADSVKDYYDLITGSRRYAAAVNATDARTAITAIKEGGYATSPTYVTNVMAVIDSNNLTQYDNVVTGNAEPQPAESKSAEELAQEIINGTWGNNPERRENITAKYGAAAYEAAQAIVNQKAGATEPAKPSKSTEELAQEIINGAWGSNPERRENITAKYGAAAYEAAQARVNEIMGVAAIKSKTAEELADEIIKGKWGSNPERRENITAKYGAAAYKAAQAIVNKRMG
Physico‐chemical
properties
protein length:323 AA
molecular weight:34528,1 Da
isoelectric point:6,51
hydropathy:-0,42
Representative Protein Details
Accession
5YKpd
Protein name
5YKpd
Sequence length
327 AA
Molecular weight
34993,17160 Da
Isoelectric point
4,78126
Sequence
MNKQEFLQLIVPLAQAEAKRRKDAGTGFVLPSVCIGQAALETGWGGSSLMTKANAFFGIKATASWGGKVFSSKTQECYDNVNYTTITAAFRAYDTPADSVKDYYDLITGSTRYAAAVNVTDARTAITAIKEGGYATSPTYVTNVMAVIDSNNLTQYDNVVTGNAEPQPAESKSAEELAQEIINGVWGNNPERRENITAQYGAAAYEAAQAIVNQRAGATEEPAKPSKSAEELAQEIINGVWGNNPERRENITAQYGAAAYEAAQAIVNQRAGATEEPAKPSKSAEELAQEIINGVWGNNPERRENITAQYGAAAYEAAQAIVNERIG
Other Proteins in cluster: phalp2_6201
Total (incl. this protein): 71 Avg length: 278,3 Avg pI: 7,37
Protein ID Length (AA) pI
5YKpd 327 4,78126
19iYT 231 9,01270
1IoV2 240 8,51693
1cNxQ 243 9,36037
1gxaE 242 9,14963
1kikr 259 9,33491
21Aq8 249 9,42890
23HY5 246 9,31093
23cdh 259 8,87602
2olrC 241 9,33536
3JcQg 324 4,84646
3TFV7 245 9,45276
3Wz64 243 9,34967
3bSLR 244 8,91155
3gWXN 245 9,43838
3kTnl 231 8,91361
3ldzx 323 5,88269
3rTLh 324 4,85447
3sEaL 325 4,75341
3tmv6 230 8,96473
3xLVG 324 4,75330
4yqBT 255 9,14602
4yw5l 272 9,33465
5B2T 232 9,20152
5KLOh 233 9,03436
5KbdE 324 4,89852
5MTUI 185 8,98253
5NbuW 234 9,14827
5OSK6 323 5,87439
5Q5gF 269 8,34177
5SOLZ 324 4,89852
5TmyL 271 4,92086
5UnvO 324 4,95672
5WK57 324 4,70265
61EfI 324 4,90716
65ltJ 324 4,74517
665ff 325 5,87439
68wtl 324 4,89852
69xFG 258 9,11810
6bC02 324 4,76279
6cf9m 323 5,88269
6decl 231 9,07285
6eWT8 258 8,92753
6esfs 324 4,89852
6fXmk 324 4,89852
6jdn9 231 9,13506
6lpxT 230 9,03726
6mBsu 324 4,89852
6mDoA 231 9,13506
6n0Ib 324 4,89852
6nA7E 325 5,58508
6ph5T 324 5,01299
6rJWk 299 4,71777
6s5VG 324 5,87439
7WLbs 259 9,35251
7X0Fp 324 4,76188
7Y49P 255 9,10508
7ZFey 271 5,76327
7aLvw 246 9,39403
7xVbL 324 4,64428
82zjJ 258 9,20649
8lzHz 266 9,54069
8pWky 232 9,00406
8puAB 232 9,10566
8rCFu 324 4,89062
8s6qG 255 9,16014
DO0a 323 8,28885
o315 237 9,48647
obUI 258 9,18708
xCFH 258 9,05608
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_35516
JUJC
 21 50,9% 214 1.091E-78
2 phalp2_3102
419EZ
 42 39,5% 215 2.465E-48
3 phalp2_29953
8uJbN
 74 37,9% 237 1.323E-39
4 phalp2_10427
21C3Q
 5 26,0% 296 3.046E-17
5 phalp2_28852
56cnG
 1 28,6% 223 1.130E-12

Domains

Domains [InterPro]
GLUCO
CW_7
CW_7
CW_7
Representative sequence (used for alignment): 5YKpd (327 AA)
Member sequence: A0A8S5PYR6 (323 AA)
1 327 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated
Pfam accessions: PF01832, PF08230

Taxonomy

  Name Taxonomy ID Lineage
Phage Myoviridae sp. ctv9K3
[NCBI] 		2825203 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015541 [NCBI]
CDS location
range 570 -> 1541
strand -
CDS
ATGAACAAACAGGAGTTTTTATCGTTAATCGTACCACTTGCACAGGCAGAGGCAAAAAGAAGAAAAGACACAGGCACAGGCTTTGTACTTCCTAGCGTGTGTGTCGGACAGGCAGCATTAGAGACAGGCTGGGGCGGCTCTAGCCTTATGACTAAGGCTAACGCATTTTTCGGCATTAAGGCTACTGCGAGCTGGGGCGGCAAAGTGTTTAGCTCTAAAACGCAGGAGTGCTACGACAGTGTTACTTACACAACAATTACAGCAGCATTTAGAGCATACGACACACCGGCAGACAGCGTAAAAGATTATTACGACCTTATCACAGGCAGCAGACGTTACGCAGCCGCAGTAAATGCGACAGACGCACGTACAGCTATTACAGCCATTAAAGAGGGCGGCTATGCCACAAGCCCTACATACGTAACAAATGTTATGGCGGTTATTGACAGCAACAACTTAACACAGTACGATAATGTGGTAACAGGAAATGCAGAGCCACAGCCAGCGGAAAGCAAGAGCGCCGAAGAGCTGGCACAGGAGATTATTAACGGCACATGGGGAAATAACCCAGAACGCCGCGAGAATATCACAGCCAAGTACGGCGCAGCAGCATACGAGGCAGCGCAGGCTATCGTAAACCAGAAAGCAGGAGCAACAGAACCGGCAAAGCCAAGCAAGAGCACCGAAGAGCTGGCGCAGGAGATTATAAACGGCGCATGGGGCAGCAATCCAGAACGCCGCGAGAATATCACAGCCAAGTACGGCGCAGCAGCATACGAGGCAGCACAGGCGCGCGTAAACGAGATTATGGGCGTAGCTGCCATTAAGAGCAAAACAGCCGAAGAGCTGGCAGACGAGATTATTAAAGGCAAGTGGGGCAGCAATCCAGAACGCCGCGAGAATATCACAGCCAAGTACGGCGCAGCAGCATACAAAGCAGCACAGGCTATCGTAAACAAGCGCATGGGGTAA

Gene Ontology

Description Category Evidence (source)
GO:0004040 amidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (5YKpd) rather than this protein.
PDB ID
5YKpd
Method AlphaFoldv2
Resolution 85.17
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50