Protein

Protein accession
A0A8S5PXW6 [UniProt]
Representative
88Wg9
Source
UniProt (cluster: phalp2_29903)
Protein name
NlpC/P60 family
Lysin probability
100%
PhaLP type
endolysin
Probability: 99% (predicted by ML model)
Protein sequence
MAWDDTAKKVAIKAIGTVESSMRYDSINYNDPITVGIAQWYGPRAADIIKKMGAKHASEYAGVASSLMSDLNSHGNDSWWTNRWLSRLEGNSLLPLLRAGAAEQDAQLVADLEAYFQAARNVGIDPNGNTDTFIYFCVMYHQGPRYAIRVMNRCGGSASLAAVHHACLNDGVLGKYPNRYNQAYSIIKNHDTSGVSTPGTPAPQNPGNGGSGGATNGGTNAGSVTEITRDGSGQLYLRTSSGLVTAQPTNNHNRWILPQNSISNGGSAATPDNGGGGGGGGTPPPPGGGTTAQLVFKWMYDRQMKFAYRQAPGRLNPDQSGFGDCSSTIWRAYKDVAGINVGTWTGDQYNRGREVVRGSGMPSAAQIALMQVADMIVMSWGDPYPNTDHVEMYTGDGVHTIGHGGPGNGPHINPLAMLRKASWWTVRRHL
Physico‐chemical
properties
protein length:430 AA
molecular weight:45904,6 Da
isoelectric point:8,54
hydropathy:-0,46
Representative Protein Details
Accession
88Wg9
Protein name
88Wg9
Sequence length
221 AA
Molecular weight
23055,52610 Da
Isoelectric point
9,24195
Sequence
MARINGGSNAGSLQSAWTDGSGMLHLKTTSGWVTGYPTPNSRVWLTAPNKVSSGGSAPTPGNAGGGTPGGGTPGGGGADAKRAAVVKWMTDRQYKFAYLQAPGRLNPDSSGFGDCSSTCYRAYMDVCGINPGTWTGDMYFRGTQVARGSGMPSSAQIAAMKAADLIVMSWDDPYPNTDHVEMYMGDGAHTIGHGGPRRGPHINSIGMLAGAAWWTVRRHIN
Other Proteins in cluster: phalp2_29903
Total (incl. this protein): 8 Avg length: 290,0 Avg pI: 8,79
Protein ID Length (AA) pI
88Wg9 221 9,24195
60sKW 288 8,76269
6fVgC 226 9,51104
7UNHV 189 8,45266
NtUd 242 8,76714
rkXg 292 8,61286
A0A8S5LFJ9 432 8,40818
Similar Clusters (pHMM search)
# Cluster # Members Identity (%) Alignment Length E-value
1 phalp2_633
1cJ8V
 6 47,8% 163 1.547E-44
2 phalp2_6349
7qJkP
 2 34,2% 152 3.835E-25
3 phalp2_27227
3IaKa
 2 29,0% 186 2.664E-18
4 phalp2_26926
4yij8
 15 30,2% 142 3.300E-12

Domains

Domains [InterPro]
Unannotated
Unannotated
Representative sequence (used for alignment): 88Wg9 (221 AA)
Member sequence: A0A8S5PXW6 (430 AA)
1 221 AA (representative)
Domain positions follow the representative sequence above; the member sequence bar is scaled to the same axis.
Legend: EAD CBD Linker Disordered Unannotated

Taxonomy

  Name Taxonomy ID Lineage
Phage Podoviridae sp. ctXSp1
[NCBI] 		2825256 No lineage information
Host No host information

Coding sequence (CDS)

Coding sequence (CDS)
CDS Source ID
[NCBI]
CDS Source
BK015539 [NCBI]
CDS location
range 12154 -> 13446
strand +
CDS
ATGGCATGGGATGACACTGCGAAGAAAGTCGCAATCAAGGCAATTGGTACTGTCGAAAGCTCTATGCGTTATGACAGTATCAATTATAACGACCCCATTACCGTTGGAATTGCTCAATGGTATGGGCCGCGTGCCGCCGACATCATTAAGAAAATGGGTGCGAAGCACGCAAGCGAATATGCGGGCGTAGCGTCATCCCTTATGTCAGACCTCAACAGCCACGGGAATGATTCGTGGTGGACTAATCGGTGGCTGTCCCGCCTGGAAGGAAACAGTCTTCTACCTCTCCTCCGGGCGGGCGCCGCCGAACAGGACGCGCAATTGGTCGCTGACCTGGAAGCTTATTTCCAAGCGGCCAGGAACGTGGGCATTGACCCCAATGGAAACACGGACACATTCATCTATTTCTGCGTCATGTATCACCAGGGGCCGCGCTATGCGATCCGTGTGATGAACCGGTGCGGTGGCAGCGCGTCCCTAGCCGCCGTCCACCACGCGTGCCTGAATGACGGTGTACTGGGAAAATACCCGAACCGCTATAACCAGGCGTATAGCATCATCAAGAATCACGACACGTCCGGTGTTTCCACGCCCGGCACGCCCGCACCCCAAAACCCCGGCAACGGCGGGAGCGGCGGGGCCACCAACGGTGGGACGAATGCTGGGAGTGTCACTGAGATTACGCGCGACGGCAGCGGGCAGCTCTACCTGAGAACCTCCTCCGGACTGGTGACGGCCCAGCCGACGAATAATCACAACAGGTGGATATTGCCTCAAAACAGCATTTCCAACGGCGGCAGTGCCGCTACCCCTGACAACGGCGGGGGCGGTGGGGGAGGGGGTACTCCTCCCCCGCCCGGCGGCGGGACCACTGCGCAACTGGTTTTCAAATGGATGTATGACAGGCAGATGAAATTTGCGTACCGGCAGGCTCCAGGGCGGTTGAACCCGGACCAATCAGGTTTCGGGGATTGCTCCAGCACTATCTGGCGTGCCTATAAGGACGTCGCCGGAATCAATGTCGGCACCTGGACGGGTGACCAATATAACCGGGGCCGTGAAGTAGTGCGCGGTTCCGGCATGCCGTCGGCCGCACAGATCGCTCTCATGCAAGTCGCTGACATGATTGTCATGTCTTGGGGCGATCCCTACCCGAACACGGATCACGTTGAGATGTATACGGGTGACGGTGTGCATACTATTGGGCACGGCGGTCCCGGTAATGGACCGCACATTAACCCGCTGGCTATGCTCCGTAAGGCTAGTTGGTGGACGGTGAGGAGACACTTGTGA

Gene Ontology

Description Category Evidence (source)
GO:0001897 symbiont-mediated cytolysis of host cell biological process None (UniProt)
GO:0008234 cysteine-type peptidase activity molecular function None (UniProt)

Enzymatic activity

No enzymatic activity data available.

Tertiary structure

No tertiary structures available for this protein.

The structures below correspond to the cluster representative (88Wg9) rather than this protein.
PDB ID
88Wg9
Method AlphaFoldv2
Resolution 75.85
Chain position -
Model Confidence
Very high
pLDDT > 90
High
90 > pLDDT > 70
Low
70 > pLDDT > 50
Very low
pLDDT < 50